Plasmid adjuvant compositions and methods for enhancing an immune response to a coadministered immunogen are described. The plasmid adjuvants include a combination of cytokines and chemokines designed to elicit an enhanced immune response. Particular combinations can be provided to generate a Th1 and/or a Th2 immune response.
High-Throughput Method Of Dna Immunogen Preparation And Immunization
Maoxin Tian - Burlingame CA, US Mark Selby - Burlingame CA, US Jang Han - Burlingame CA, US William Rutter - Burlingame CA, US Yifel Zhu - Burlingame CA, US
International Classification:
C12Q001/68 C12P021/04
US Classification:
435006000
Abstract:
A high-throughput process of generating expression-competent, antigen-encoding immunogen DNA through amplification methodology including ligation-assisted PCR is described, as well as the use of the DNA for methods of DNA immunization. Also described is an adjuvant plasmid to enhance antibody production.
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Company / Classification
Phones & Addresses
Maoxin Tian Owner
Tia, Maoxin Commercial Physical Research
378 Richmond Dr, Millbrae, CA 94030
Maoxin Tian
Miratope LLC Biotechnology Development and Marketing: · Commercial Physical Research