Luke Daniel Walker

US Patent:

20200188401, Jun 18, 2020

Filed:

Apr 27, 2018

Appl. No.:

16/607850

Inventors:

- Bothell WA, US
Luke Walker - Bothell WA, US

International Classification:

A61K 31/517
A61K 31/7068
A61K 39/395
A61P 35/00

Abstract:

In one aspect, the present invention provides a method for treating or ameliorating the effects of a HER2 positive cancer in a subject. In some embodiments, the method comprises administering a combination therapy comprising an anti-HER2 antibody and tucatinib. In some embodiments, the method further comprises administering a chemotherapeutic agent (e.g., an antimetabolite) to the subject. Pharmaceutical compositions and kits are also provided herein.

US Patent:

20190329348, Oct 31, 2019

Filed:

Jul 11, 2019

Appl. No.:

16/508669

Inventors:

- Columbus OH, US
Ying Lu - Columbus OH, US
Luke Walker - Columbus OH, US
Menachem Kimchi - Westville OH, US

International Classification:

B23K 11/20
B23K 11/11

Abstract:

An example method for joining metals is described herein. The method can include forming an intermediate joint between a light metal member and a metal insert, where the intermediate joint is formed using a solid state welding process. The method can also include forming a primary joint between the light metal member and a high strength steel member, where the primary joint is formed using a welding process that produces coalescence at a temperature above the melting point of the light metal member and/or the high-strength steel member.