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Lawrence J Bonassar

age ~57

from Ithaca, NY

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Also known as:
  • Larry J Bonassar
  • Lawren Bonassar
Phone and address:
5 John St, Ithaca, NY 14850
607 256-7980
Related to:
Connected to:

Lawrence Bonassar Phones & Addresses

  • 5 John St, Ithaca, NY 14850 • 607 256-7980
  • 164 Grant St, Framingham, MA 01702 • 508 620-6156
  • 386 Central St, Acton, MA 01720 • 978 266-9880
  • 50 Foskett St, Somerville, MA 02144 • 617 625-1985

Work

  • Position:
    Professional/Technical

Education

  • Degree:
    Graduate or professional degree

Us Patents

  • Injection Molding Of Living Tissues

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  • US Patent:
    6773713, Aug 10, 2004
  • Filed:
    Feb 21, 2002
  • Appl. No.:
    10/081897
  • Inventors:
    Lawrence J. Bonassar - Acton MA
    Jon A. Rowley - Chapel Hill NC
    David J. Mooney - Ann Arbor MI
  • Assignee:
    University of Massachusetts - Boston MA
  • International Classification:
    A61F 202
  • US Classification:
    424423, 424424, 424425, 424426
  • Abstract:
    The invention features methods of making living tissue constructs having a predetermined shape by providing a negative mold having a defined shape; suspending isolated tissue precursor cells in a hydrogel to form a liquid hydrogel-precursor cell composition; introducing the liquid hydrogel-precursor cell composition into the mold; inducing gel formation to solidify the liquid hydrogel-precursor cell composition to form a living tissue construct; and removing the living tissue construct from the mold after gel formation.

  • Modular Fabrication Systems And Methods

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  • US Patent:
    7625198, Dec 1, 2009
  • Filed:
    Aug 10, 2005
  • Appl. No.:
    11/200994
  • Inventors:
    Hod Lipson - Ithaca NY, US
    Lawrence Bonassar - Ithaca NY, US
    Daniel L. Cohen - Ithaca NY, US
    Evan Malone - Ithaca NY, US
  • Assignee:
    Cornell Research Foundation, Inc. - Ithaca NY
  • International Classification:
    B29B 15/00
    B28B 1/00
  • US Classification:
    425174, 425169, 425375
  • Abstract:
    The present invention relates to an article fabrication system having a plurality of material deposition tools containing one or more materials useful in fabricating the article, and a material deposition device having a tool interface for receiving one of the material deposition tools. A system controller is operably connected to the material deposition device to control operation of the material deposition device. Also disclosed is a method of fabricating an article using the system of the invention and a method of fabricating a living three-dimensional structure.

  • Modular Fabrication Systems And Methods

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  • US Patent:
    7939003, May 10, 2011
  • Filed:
    Aug 10, 2005
  • Appl. No.:
    11/201057
  • Inventors:
    Lawrence Bonassar - Ithaca NY, US
    Hod Lipson - Ithaca NY, US
    Daniel L. Cohen - Ithaca NY, US
    Evan Malone - Ithaca NY, US
  • Assignee:
    Cornell Research Foundation, Inc. - Ithaca NY
  • International Classification:
    B28B 1/14
  • US Classification:
    264308, 438 1, 118708, 101491
  • Abstract:
    The present invention relates to an article fabrication system having a plurality of material deposition tools containing one or more materials useful in fabricating the article, and a material deposition device having a tool interface for receiving one of the material deposition tools. A system controller is operably connected to the material deposition device to control operation of the material deposition device. Also disclosed is a method of fabricating an article using the system of the invention and a method of fabricating a living three-dimensional structure.

  • Biaxial Load Cell With Highly Anisotropic Force Resolutions

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  • US Patent:
    7958790, Jun 14, 2011
  • Filed:
    Sep 28, 2006
  • Appl. No.:
    11/536405
  • Inventors:
    Jason Gleghorn - Ithaca NY, US
    Lawrence Bonassar - Ithaca NY, US
  • Assignee:
    Cornell Research Foundation, Inc. - Ithaca NY
  • International Classification:
    G01L 1/04
    G01N 3/56
  • US Classification:
    73862632, 73 9, 73 10, 73862634, 73862627, 73862621
  • Abstract:
    A load cell for measuring extremely low level, anisotropic biaxial loads is disclosed. The system includes at least one load cell of a specific geometry and dimension which, when mounted, provides a rotationless system accurately transmitting both normal and shearing strains to strain gauges mounted thereon. More specifically, by shaping the load cell so as to concentrate the strains imposed thereon, detection of extremely minute loads, such as coefficients of friction, can be measured.

  • Modular Fabrication Systems And Methods

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  • US Patent:
    8636938, Jan 28, 2014
  • Filed:
    Mar 21, 2011
  • Appl. No.:
    13/052787
  • Inventors:
    Lawrence Bonassar - Ithaca NY, US
    Hod Lipson - Ithaca NY, US
    Daniel L. Cohen - Ithaca NY, US
    Evan Malone - Ithaca NY, US
  • Assignee:
    Cornell Research Foundation, Inc. - Ithaca NY
  • International Classification:
    B28B 1/14
  • US Classification:
    264308, 438 1, 118708, 101491
  • Abstract:
    The present invention relates to an article fabrication system having a plurality of material deposition tools containing one or more materials useful in fabricating the article, and a material deposition device having a tool interface for receiving one of the material deposition tools. A system controller is operably connected to the material deposition device to control operation of the material deposition device. Also disclosed is a method of fabricating an article using the system of the invention and a method of fabricating a living three-dimensional structure.

  • Composition For The Delivery Of Live Cells And Methods Of Use

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  • US Patent:
    20020025308, Feb 28, 2002
  • Filed:
    Jul 9, 2001
  • Appl. No.:
    09/901495
  • Inventors:
    Henry Costantino - Brookline MA, US
    Lawrence Bonassar - Acton MA, US
    Mark Tracy - Arlington MA, US
  • Assignee:
    Alkermes Controlled Therapeutics, Inc. - Cambridge MA
  • International Classification:
    A61K048/00
    A61K009/14
    A61K009/16
  • US Classification:
    424/093210, 424/489000, 424/493000, 424/497000
  • Abstract:
    The invention relates to an improved method for administering live cells to a patient and compositions useful in the method. The composition comprises live cells and biocompatible, biodegradable polymer microparticles. The cells and microparticles of the cell/microparticle composition can be contacted immediately prior to administration, or can be contacted in culture for a specified period of time prior to administration. In the method of the invention, an effective amount of the cell/microparticle composition is administered to a patient in need thereof by injection to a treatment site of the patient to provide a therapeutic effect in the patient. The therapeutic effect can be, for example, the formation of new tissue at the treatment site, or the production and secretion of a biologically active secretory molecule at the treatment site. The composition comprising lives cells and biocompatible, biodegradable polymer microparticles can be used in a method of generating new tissue in vitro. The method comprises placing the composition in a cell culture chamber under conditions wherein a coherent mass of tissue is formed. In a particular embodiment, the culture chamber is in a specified shape which results in the generation tissue having said shape.

  • Tympanic Membrane Patch

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  • US Patent:
    20020151974, Oct 17, 2002
  • Filed:
    Feb 21, 2002
  • Appl. No.:
    10/081360
  • Inventors:
    Lawrence Bonassar - Acton MA, US
    Morgan Hott - Worcester MA, US
    Clifford Megerian - Westborough MA, US
    Richard Beane - Hingham MA, US
  • International Classification:
    A61F002/18
    A61F002/02
  • US Classification:
    623/010000, 264/006000, 623/023720, 435/397000
  • Abstract:
    The invention features methods of making living tissue constructs that can be used to repair perforations in tympanic membranes, the repair constructs themselves, and methods of repair.

  • Composition For The Delivery Of Live Cells And Methods Of Use Thereof

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  • US Patent:
    20040234547, Nov 25, 2004
  • Filed:
    Feb 23, 2004
  • Appl. No.:
    10/784908
  • Inventors:
    Henry Costantino - Grantham NH, US
    Lawrence Bonassar - Acton MA, US
    Mark Tracy - Arlington MA, US
  • International Classification:
    A61K039/00
    A61F002/00
    C12N005/08
  • US Classification:
    424/198100, 435/372000, 424/093700
  • Abstract:
    The invention relates to an improved method for administering live cells to a patient and compositions useful in the method. The composition comprises live cells and biocompatible, biodegradable polymer microparticles. The cells and microparticles of the cell/microparticle composition can be contacted immediately prior to administration, or can be contacted in culture for a specified period of time prior to administration. In the method of the invention, an effective amount of the cell/microparticle composition is administered to a patient in need thereof by injection to a treatment site of the patient to provide a therapeutic effect in the patient. The therapeutic effect can be, for example, the formation of new tissue at the treatment site, or the production and secretion of a biologically active secretory molecule at the treatment site. The therapeutic effect resulting from injection of the cell/microparticle composition into a treatment site, is determined by the type of cell present in the composition. The composition comprising lives cells and biocompatible, biodegradable polymer microparticles can further comprise a biologically active agent. In a preferred embodiment, the biologically active agent is incorporated into the microparticle. The biologically active agent can be, for example, factors which modulate cell growth.

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News

Scientists Grow New Ears For Children With Defect

Scientists grow new ears for children with defect

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  • The delivery of shaped cartilage for the reconstruction of microtia has been a goal of the tissue engineering community for more than two decades, said Lawrence Bonassar, a professor of biomedical engineering and mechanical and aerospace engineering at Cornell University in Ithaca, New York, who w
  • Date: Jan 30, 2018
  • Category: Health
  • Source: Google

Cornell bioengineers print human ears

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  • a day or so to print it, 30 minutes to inject the gel, and we can remove the ear 15 minutes later. We trim the ear and then let it culture for several days in nourishing cell culture media before it is implanted," said co-lead author Lawrence Bonassar, associate professor of biomedical engineering.
  • Date: Feb 22, 2013
  • Category: Health
  • Source: Google

U.S. bioengineers create artificial ear

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  • Co-lead authors Lawrence Bonassar, associate professor of biomedical engineering, of Cornell University and Dr. Jason Spector, director of the Laboratory for Bioregenerative Medicine and Surgery and associate professor of plastic surgery at Weill Cornell in New York City, said the finding gives new
  • Date: Feb 21, 2013
  • Category: Health
  • Source: Google

How to make a replacement ear in just one week

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  • The process is fast, Cornells Lawrence Bonassar says in a news release. It takes half a day to design the mold, a day or so to print it, 30 minutes to inject the gel and we can remove the ear 15 minutes later. We trim the ear and then let it culture for several days in a nourishing cell culture
  • Date: Feb 21, 2013
  • Category: Health
  • Source: Google

Cornell Researchers Grow A Realistic Bio-Engineered Human Ear

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  • The PLOS ONE study's lead authors have been working on bioengineering human tissues for reconstruction since 2007. Cornell bioengineering professor and co-author Lawrence Bonassar explains part of the 3-D printing process in the video below:
  • Date: Feb 21, 2013
  • Category: Health
  • Source: Google

Artificial ear grown in lab: scientists

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  • Co-author Lawrence Bonassar, associate professor of biomedical engineering, said: "This is such a win-win for both medicine and basic science, demonstrating what we can achieve when we work together.
  • Date: Feb 21, 2013
  • Category: Health
  • Source: Google

3-D Printed Body Parts, Finally!

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  • Lawrence Bonassar, associate professor of biomedical engineering at Cornell, Spector co-authored a study published in PLOS ONE detailing their innovative methods, which vastly improve on the two previous options for treatment -- the first being the creation of an implant using an artificial, Styrof
  • Date: Feb 20, 2013
  • Source: Google

Scientists use 3-D printing to help grow an ear

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  • If it pans out, "this enables us to rapidly customize implants for whoever needs them," said Cornell biomedical engineer Lawrence Bonassar, who co-authored the research published online in the journal PLoS One.
  • Date: Feb 20, 2013
  • Category: Health
  • Source: Google
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