Jong Un Choi

Address:

3707 Nicholas Dr APT B4, Lafayette, IN 47909

VIN:

2T3YF4DV8AW043996

Make:

TOYOTA

Model:

RAV4

Year:

2010

US Patent:

20130105328, May 2, 2013

Filed:

Sep 14, 2012

Appl. No.:

13/620554

Inventors:

Jong Hyun Choi - West Lafayette IN, US
Jonathan C. Claussen - Lafayelle IN, US
Alfred R. Diggs - Chicago IL, US
Jin Shi - San Diego CA, US

Assignee:

Purdue Research Foundation - West Lafayette IN

International Classification:

C12Q 1/00
C12Q 1/68

US Classification:

205109, 20440301, 20440314, 2057775, 977750, 977892, 977904

Abstract:

Glucose and ATP biosensors have important applications in diagnostics and research. Combining single-walled carbon nanotubes (SWCNTs) with Pt nanoparticles can significantly enhance the performance of electrochemical biosensors. This disclosure illustrates the use of single-stranded DNA (ssDNA) to modify SWCNTs to increase SWCNT solubility in water. Multiple embodiments with this configuration allows for exploration of new schemes of combining ssDNASWCNT and Pt black in aqueous media systems. These embodiments resulted in a nanocomposite with enhanced biosensor performance. The ssDNA-SWCNT/Pt black nanocomposite constructed by a layered scheme proved most effective in terms of biosensor activity. The key feature of this structure and method of use is the exploitation of ssDNASWCNTs as molecular templates for Pt black electrodeposition. Glucose and ATP microbiosensors fabricated utilizing this structure and method of use exhibited high sensitivity, wide linear range and low limit of detection.