James Etta Carson

US Patent:

6548478, Apr 15, 2003

Filed:

Oct 24, 2001

Appl. No.:

10/038309

Inventors:

James W. Carson - New York NY
Frederic W. Chapin - New York NY
Charles H. Fahrenholz - New York NY

Assignee:

Pfizer Inc. - New York NY

International Classification:

A61K 3815

US Classification:

514 9, 514310

Abstract:

A mixture comprising: a) virginiamycin; b) a pharmaceutically acceptable and substantially anhydrous wetting agent including sodium lauryl sulfate; c) a sufficient amount of pharmaceutically acceptable buffering agent to provide a pH of from about 3 0 to about 7. 0 when said mixture is added to water; and d) from about 0. 5 weight percent to about 10 0 weight percent colloidal silicon dioxide, wherein the ratio of the weight percent of (b) to the weight percent of (a) percent by weight is at least about 1. 5:1. The mixture is designed to be added to water to produce a stable suspension of the virginiamycin, which can then be applied to, for example, feed grain.