Hyun W Cho

US Patent:

6654625, Nov 25, 2003

Filed:

Jun 16, 2000

Appl. No.:

09/595708

Inventors:

James L. Say - Alameda CA
Michael F. Tomasco - Danville CA
Jay D. Audett - Mountain View CA
Hyun Cho - Berkeley CA
Duane O. Yamasaki - El Cerrito CA
Adam Heller - Austin TX

Assignee:

TheraSense, Inc. - Alameda CA

International Classification:

A61B 505

US Classification:

600347, 600345, 600365

Abstract:

An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. The sensor is configured and arranged for implantation into the body of a mammal for contact with body fluids of the mammal. The analyte diffuses to the sensing element via the edge of the sensor, thereby restricting mass transport of the analyte to the sensing element. This is because the solution-contacting surface area of the sensor edge is much smaller than an open face of the sensing layer.

US Patent:

6932894, Aug 23, 2005

Filed:

May 14, 2002

Appl. No.:

10/146518

Inventors:

Fei Mao - Fremont CA, US
Hyun Cho - Berkeley CA, US

Assignee:

TheraSense, Inc. - Alameda CA

International Classification:

G01N027/327
A61B005/05
B01D039/00

US Classification:

20440306, 20440305, 600347, 21050037

Abstract:

Novel membranes comprising various polymers containing heterocyclic nitrogen groups are described. These membranes are usefully employed in electrochemical sensors, such as amperometric biosensors. More particularly, these membranes effectively regulate a flux of analyte to a measurement electrode in an electrochemical sensor, thereby improving the functioning of the electrochemical sensor over a significant range of analyte concentrations. Electrochemical sensors equipped with such membranes are also described.

US Patent:

6975893, Dec 13, 2005

Filed:

Nov 25, 2003

Appl. No.:

10/723381

Inventors:

James L. Say - Alameda CA, US
Michael F. Tomasco - Danville CA, US
Jay D. Audett - Mountain View CA, US
Hyun Cho - Berkeley CA, US
Duane O. Yamasaki - El Cerrito CA, US
Adam Heller - Austin TX, US

Assignee:

TheraSense, Inc. - Alameda CA

International Classification:

A61B005/05

US Classification:

600347, 600345, 600365, 600373

Abstract:

An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. The sensor is configured and arranged for implantation into the body of a mammal for contact with body fluids of the mammal. The analyte diffuses to the sensing element via the edge of the sensor, thereby restricting mass transport of the analyte to the sensing element. This is because the solution-contacting surface area of the sensor edge is much smaller than an open face of the sensing layer.

US Patent:

7670470, Mar 2, 2010

Filed:

Jul 1, 2005

Appl. No.:

11/174222

Inventors:

Fei Mao - Fremont CA, US
Hyun Cho - Berkeley CA, US

Assignee:

Abbott Diabetes Care Inc. - Alameda CA

International Classification:

G01N 27/327
B01D 71/06
G01N 27/31

US Classification:

204400, 20440305, 20440306, 204418, 204431, 21050027

Abstract:

Novel membranes comprising various polymers containing heterocyclic nitrogen groups are described. These membranes are usefully employed in electrochemical sensors, such as amperometric biosensors. More particularly, these membranes effectively regulate a flux of analyte to a measurement electrode in an electrochemical sensor, thereby improving the functioning of the electrochemical sensor over a significant range of analyte concentrations. Electrochemical sensors equipped wish such membranes are also described.

US Patent:

8147666, Apr 3, 2012

Filed:

Aug 20, 2009

Appl. No.:

12/544794

Inventors:

Fei Mao - Fremont CA, US
Hyun Cho - Berkeley CA, US

Assignee:

Abbott Diabetes Care Inc. - Alameda CA

International Classification:

G01N 27/327
B01D 3/00

US Classification:

20440305, 20440306, 427 213

Abstract:

Novel membranes comprising various polymers containing heterocyclic nitrogen groups are described. These membranes are usefully employed in electrochemical sensors, such as amperometric biosensors. More particularly, these membranes effectively regulate a flux of analyte to a measurement electrode in an electrochemical sensor, thereby improving the functioning of the electrochemical sensor over a significant range of analyte concentrations. Electrochemical sensors equipped with such membranes are also described.

US Patent:

8160670, Apr 17, 2012

Filed:

Jul 3, 2008

Appl. No.:

12/167820

Inventors:

Tianmei Ouyang - Fremont CA, US
Zenghe Liu - Alameda CA, US
Hyun Cho - Berkeley CA, US
Benjamin J. Feldman - Oakland CA, US

Assignee:

Abbott Diabetes Care Inc. - Alameda CA

International Classification:

G01N 27/26
C12Q 1/00
A61B 5/05

US Classification:

600347, 600345, 600365, 20440301, 20440314

Abstract:

An analyte sensor including an antiglycolytic agent or a precursor thereof and a chelating agent that stabilizes the antiglycolytic agent positioned proximate to the working electrode of the sensor. Also provided are systems and methods of using the electrochemical analyte sensors in analyte monitoring.

US Patent:

8268143, Sep 18, 2012

Filed:

Jul 14, 2008

Appl. No.:

12/172589

Inventors:

Zenghe Liu - Alameda CA, US
Tianmei Ouyang - Fremont CA, US
Hyun Cho - Berkeley CA, US
Yohannes Goti - Oakland CA, US
Benjamin J. Feldman - Oakland CA, US
Fei Mao - Fremont CA, US
Adam Heller - Austin TX, US

Assignee:

Abbott Diabetes Care Inc. - Alameda CA

International Classification:

C12Q 1/32

US Classification:

20440301, 20440302, 20440303, 20440304, 20440305, 20440306, 20440307, 20440308, 20440309, 20440312, 20440311

Abstract:

The present invention provides an electrochemical sensor having a sensing chemistry that operates substantially free of any “oxygen effect”. The electrochemical sensors are useful in determining the level of an analyte in a biological sample from a subject. The present invention also provides sensor assemblies including the electrochemical sensors as well as methods of using the same.

US Patent:

8377271, Feb 19, 2013

Filed:

Sep 29, 2010

Appl. No.:

12/893756

Inventors:

Fei Mao - Fremont CA, US
Hyun Cho - Berkeley CA, US

Assignee:

Abbott Diabetes Care Inc. - Alameda CA

International Classification:

G01N 27/327

US Classification:

20440305, 600345, 20440314

Abstract:

Novel membranes comprising various polymers containing heterocyclic nitrogen groups are described. These membranes are usefully employed in electrochemical sensors, such as amperometric biosensors. More particularly, these membranes effectively regulate a flux of analyte to a measurement electrode in an electrochemical sensor, thereby improving the functioning of the electrochemical sensor over a significant range of analyte concentrations. Electrochemical sensors equipped with such membranes are also described.