President and CEO at Protein Advances Inc., Vice President of Adjuvant Technologies at Infectious Disease Research Institute
Location:
Greater Seattle Area
Industry:
Biotechnology
Work:
Protein Advances Inc. since May 2004
President and CEO
Infectious Disease Research Institute since 2004
Vice President of Adjuvant Technologies
Dharma Therapeutics 2005 - 2006
Vice President for Research and Development
Corixa Corp 1998 - 2004
Group Leader
Education:
Oregon Health and Science University School of Medicine 1993 - 1998
Ph.D., Biochemistry
Oregon State University 1990 - 1993
B.Sci., Biochemistry
Skills:
Biotechnology Vaccines Lifesciences Immunology Infectious Diseases Molecular Biology Drug Discovery Cell Culture Biochemistry Protein Chemistry Assay Development Cell Biology Microbiology Cell Clinical Development Bioinformatics Purification Chromatography DNA Protein Purification GLP Genomics Genetics
Tongtong Wang - Medina WA Chaitanya S. Bangur - Seattle WA Michael J. Lodes - Seattle WA Gary R. Fanger - Mill Creek WA Thomas S. Vedvick - Federal Way WA Darrick Carter - Seattle WA Marc W. Retter - Carnation WA Jane Mannion - Edmonds WA Liqun Fan - Bellevue WA Aijun Wang - Issaquah WA
Assignee:
Corixa Corporation - Seattle WA
International Classification:
C07K 1618
US Classification:
5303879
Abstract:
Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
Compositions And Methods For The Therapy And Diagnosis Of Prostate Cancer
Jiangchun Xu - Bellevue WA Davin C. Dillon - Issaquah WA Jennifer L. Mitcham - Redmond WA Susan L. Harlocker - Seattle WA Yuqiu Jiang - Kent WA Michael D. Kalos - Seattle WA Gary R. Fanger - Mill Creek WA Marc W. Retter - Carnation WA John A. Stolk - Bothell WA Craig H. Day - Seattle WA Thomas S. Vedvick - Federal Way WA Darrick Carter - Seattle WA Samuel X. Li - Redmond WA Aijun Wang - Issaquah WA Yasir A. W. Skeiky - Bellevue WA William T. Hepler - Seattle WA Robert A. Henderson - Edmonds WA
Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.
Compositions And Methods For The Therapy And Diagnosis Of Prostate Cancer
Jiangchun Xu - Bellevue WA Davin C. Dillon - Issaquah WA Jennifer L. Mitcham - Redmond WA Susan L. Harlocker - Seattle WA Yuqiu Jiang - Kent WA Michael D. Kalos - Seattle WA Gary R. Fanger - Mill Creek WA Marc W. Retter - Carnation WA John A. Stolk - Bothell WA Craig H. Day - Seattle WA Thomas S. Vedvick - Federal Way WA Darrick Carter - Seattle WA Samuel X. Li - Redmond WA Aijun Wang - Issaquah WA Yasir A. W. Skeiky - Bellevue WA William T. Hepler - Seattle WA Robert A. Henderson - Edmonds WA
Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.
Compositions And Methods For The Therapy And Diagnosis Of Prostate Cancer
Jiangchun Xu - Bellevue WA Davin C. Dillon - Issaquah WA Jennifer L. Mitcham - Redmond WA Susan L. Harlocker - Seattle WA Yuqiu Jiang - Kent WA Michael D. Kalos - Seattle WA Gary R. Fanger - Mill Creek WA Marc W. Retter - Carnation WA John A. Stolk - Bothell WA Craig H. Day - Seattle WA Thomas S. Vedvick - Federal Way WA Darrick Carter - Seattle WA Samuel X. Li - Redmond WA Aijun Wang - Issaquah WA Yasir A. W. Skeiky - Bellevue WA William T. Hepler - Seattle WA Robert A. Henderson - Edmonds WA
Assignee:
Corixa Corporation - Seattle WA
International Classification:
C12Q 168
US Classification:
435 6, 4353201, 4352523, 435325, 536 231, 536 241
Abstract:
Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
Compositions And Methods For The Therapy And Diagnosis Of Lung Cancer
Tongtong Wang - Medina WA Chaitanya S. Bangur - Seattle WA Michael J. Lodes - Seattle WA Gary R. Fanger - Mill Creek WA Thomas S. Vedvick - Federal Way WA Darrick Carter - Seattle WA Marc W. Retter - Carnation WA Jane Mannion - Edmonds WA Liqun Fan - Bellevue WA
Assignee:
Corixa Corporation - Seattle WA
International Classification:
A61K 3816
US Classification:
530350, 530300, 4241841
Abstract:
Compositions comprising isolated cancer-associated L552S polypeptides are disclosed. Such compositions can comprise, for example, portions of said cancer-associated L552S polypeptides and/or the corresponding polynucleotides encoding such portions. Illustrative uses of the compositions, for example in cancer diagnostic methods, are also provided.
Compositions And Methods For The Therapy And Diagnosis Of Lung Cancer
Tongtong Wang - Medina WA Chaitanya S. Bangur - Seattle WA Michael J. Lodes - Seattle WA Gary R. Fanger - Mill Creek WA Thomas S. Vedvick - Federal Way WA Darrick Carter - Seattle WA Marc W. Retter - Carnation WA Jane Mannion - Edmonds WA Liqun Fan - Bellevue WA
Compositions and methods for the therapy and diagnosis of cancer, such as lung cancer, are disclosed. Compositions may comprise one or more lung tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a lung tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as lung cancer. Diagnostic methods based on detecting a lung tumor protein, or mRNA encoding such a protein, in a sample are also provided.
Compositions And Methods For The Therapy And Diagnosis Of Ovarian Cancer
Jennifer L. Mitcham - Redmond WA Gordon E. King - Seattle WA Paul A. Algate - Issaquah WA Steven P. Fling - Bainbridge Island WA Marc W. Retter - Carnation WA Gary R. Fanger - Mill Creek WA Steven G. Reed - Bellevue WA Thomas S. Vedvick - Federal Way WA Darrick Carter - Seattle WA
Assignee:
Corixa Corporation - Seattle WA
International Classification:
C12Q 168
US Classification:
435 6, 4352523, 4353201, 435325, 536 231, 536 241
Abstract:
Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.
Tongtong Wang - Medina WA Chaitanya S. Bangur - Seattle WA Michael J. Lodes - Seattle WA Gary R. Fanger - Mill Creek WA Thomas S. Vedvick - Federal Way WA Darrick Carter - Seattle WA Marc W. Retter - Carnation WA Jane Mannion - Edmonds WA Liqun Fan - Bellevue WA
Assignee:
Corixa Corporation - Seattle WA
International Classification:
G01N 33574
US Classification:
435 71, 435 721, 435 723, 530300, 530350
Abstract:
Compositions and methods for the therapy and diagnosis of cancer, such as lung cancer, are disclosed. Compositions may comprise one or more lung tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a lung tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as lung cancer. Diagnostic methods based on detecting a lung tumor protein, or mRNA encoding such a protein, in a sample are also provide.