Brennan S Winkler

US Patent:

20120245100, Sep 27, 2012

Filed:

Mar 22, 2012

Appl. No.:

13/427851

Inventors:

Brennan Winkler - South Jordan UT, US
Ellen Peterson - Sandy UT, US

International Classification:

C12N 15/82
A61K 38/16
A61K 35/00
A01H 5/00

US Classification:

514 193, 4353201, 800298, 8003201, 8003202, 800313, 8003174

Abstract:

A plasmid for use in transferring a chicken anemia virus apoptin coding sequence into a plant includes a binary vector suitable for transferring DNA from to a selected plant, upstream and downstream homologous regions for targeting transfer of the DNA to a specified location in the selected plant genome, a chicken anemia virus apoptin coding sequence operationally configured adjacent to selected plant promoter and terminator segments, and an antibiotic marker coding sequence operationally configured adjacent to selected plant promoter and terminator segments. Transfer of DNA into a plant, such as , results in a plant that expresses apoptin. Cancer treatment can include ingesting plant parts containing expressed apoptin. Apoptin for use as a medicine or vaccine can be obtained from the modified plant.