Akira Hachiya from Mason, OH, age 53

Animal Model For Pigment Spots
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US Patent:

7897833, Mar 1, 2011
Filed:

Apr 18, 2007
Appl. No.:

11/785549
Inventors:

Akira Hachiya - Cincinnati OH, US
Penkanok Sriwiriyanont - Cincinnati OH, US
Assignee:

Kao Corporation - Tokyo
International Classification:

A01K 67/00
US Classification:

800 8, 800 9
Abstract:

An animal model for pigment spots in which the formation of pigment spots in human skin is faithfully simulated is provided. An animal model for pigment spots, wherein a black person's skin is grafted onto a non-human animal, is provided.

Animal Model For Hyperpigmentation
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US Patent:

7973211, Jul 5, 2011
Filed:

Mar 11, 2008
Appl. No.:

12/073869
Inventors:

Akira Hachiya - Cincinnati OH, US
Penkanok Sriwiriyanont - Cincinnati OH, US
Shinya Kasamatsu - Tochigi, JP
Assignee:

Kao Corporation - Tokyo
International Classification:

A01K 67/00
US Classification:

800 9, 800 8
Abstract:

An animal model for hyperpigmentations in which the formation of hyperpigmentations in human skin is faithfully simulated is provided. An animal model for hyperpigmentations, wherein a black person's skin is grafted onto a non-human animal, is provided.

Method For Screening An Agent For Preventing Or Ameliorating Wrinkles
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US Patent:

8088570, Jan 3, 2012
Filed:

Apr 18, 2006
Appl. No.:

11/405471
Inventors:

Tsutomu Fujimura - Ichikai-machi, JP
Takuji Kume - Tokyo, JP
Akira Hachiya - Cincinnati OH, US
Assignee:

Kao Corporation - Tokyo
International Classification:

C12Q 1/00
US Classification:

435 4
Abstract:

There is provided a screening method which can select a photoaging-preventing or improving agent or a wrinkle-preventing or improving agent with efficiency and reliability. The screening method for a photoaging- or wrinkle-preventing or improving agent selects, as a candidate, a substance inhibiting the expression of keratin 6 and/or keratin 16 genes or keratin 6 and/or keratin 16 proteins in a skin tissue or cell.

Human Photoaged Skin Model
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US Patent:

20070143866, Jun 21, 2007
Filed:

Dec 20, 2005
Appl. No.:

11/311239
Inventors:

Akira Hachiya - Cincinnati OH, US
Tsutomu Fujimura - Haga-gun, JP
Assignee:

KAO CORPORATION - Tokyo
International Classification:

A01K 67/027
C12N 5/08
US Classification:

800014000, 435366000
Abstract:

The invention provides a human photoaged skin model and an animal model which are useful for evaluating cosmetics and similar products in terms of their anti-aging or rejuvenating effect, as well as a method for producing such a skin model and such an animal model. The method of producing the human photoaged skin model is characterized in that a transplanted skin area of an immunodeficient non-human animal which has undergone transplantation of human skin is irradiated with UV-B light of 80-100 mJ/cmfor consecutive 4 to 8 weeks, and the irradiated area is left to take its own course for at least 3 weeks. A human photoaged skin model and an animal model produced through this method are also disclosed.

Human Photoaged Skin Model
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US Patent:

20080010695, Jan 10, 2008
Filed:

Jun 21, 2007
Appl. No.:

11/766522
Inventors:

Akira HACHIYA - Cincinnati OH, US
Tsutomu Fujimura - Haga-gun, JP
Assignee:

KAO CORPORATION - Tokyo
International Classification:

A01K 67/027
US Classification:

800009000
Abstract:

The present invention provides a human photoaged skin model and an animal model, and a method of making the same, for evaluating cosmetics and similar products in terms of their anti-aging or rejuvenating effect

Vasoprotective Agent
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US Patent:

20080181975, Jul 31, 2008
Filed:

Jan 31, 2007
Appl. No.:

11/700200
Inventors:

Naonobu Yoshizuka - Tochigi, JP
Yuko Fukuda - Tochigi, JP
Yasuko Amano - Tochigi, JP
Minoru Takizawa - Tochigi, JP
Hajime Soga - Tokyo, JP
Shinobu Mori - Tokyo, JP
Akira Hachiya - Cincinnati OH, US
Assignee:

Kao Corporation - Tokyo
International Classification:

A61K 36/752
A61K 36/00
A61K 36/16
A61K 36/81
A61P 7/00
A61K 36/42
A61K 36/537
US Classification:

424736, 424746, 424752, 424758, 424760, 424773
Abstract:

This invention provides a vasoprotective agent containing a plant or its extract as an effective ingredient. The plant is selected from the group consisting of rosemary, sage, geranium herb, adlai, field horsetail, bitter orange peel, fucus, burdock, dokudami, Japan pepper, Ophiopogon tuber, ginkgo, natsume and dishcloth gourd.

Method Of Evaluating Or Selecting Agents For Preventing Or Improving Pigmented Spots
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US Patent:

20090226901, Sep 10, 2009
Filed:

Mar 6, 2008
Appl. No.:

12/073568
Inventors:

Daiki Murase - Tochigi, JP
Akira Hachiya - Cincinnati OH, US
Yasuko Amano - Tochigi, JP
International Classification:

C12Q 1/68
C12Q 1/02
US Classification:

435 6, 435 29
Abstract:

The object of the present invention is to provide a method for evaluating or selecting an agent having preventive or alleviative effects on spots, which method realizes reliable and effective screening of candidate substances of the agent; a method for predicting spot formation; and a method for analyzing the condition of skin spots. The method of the present invention for evaluating or selecting an agent having preventive or alleviative effects on spots, includes evaluating a substance which suppresses a p53 activity, or an expression level of a p53 gene, a p53 target gene or an expression product thereof in an epidermal cell.

Method Of Controlling Hair Shape
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US Patent:

20090280088, Nov 12, 2009
Filed:

May 9, 2008
Appl. No.:

12/149912
Inventors:

Akira Hachiya - Cincinnati OH, US
Penkanok Sriwiriyanont - Cincinnati OH, US
International Classification:

C12Q 1/68
A61K 48/00
G01N 33/53
A61K 31/7088
A61P 17/00
US Classification:

424 932, 435 6, 436501, 435 71, 514 44 R
Abstract:

The present invention provides a method for determining or modulating hair morphology and properties of natural wavy and frizzy hair and a method for evaluating or selecting a hair morphology modulator. The present invention provides a method for modulating hair morphology, including controlling an expression of IGFBP-5 gene or IGFBP-5 protein in a human hair follicle.