Steven M Hinrichs

US Patent:

20070225918, Sep 27, 2007

Filed:

Jun 21, 2004

Appl. No.:

10/561889

Inventors:

Khalid Sayood - Lincoln NE, US
Hasan Otu - Boston MA, US
Steven Hinrichs - Omaha NE, US

International Classification:

G06F 19/00

US Classification:

702019000, 536022100

Abstract:

The present invention permits identification of biological materials following recovery of DNA using standard techniques by comparing a mathematical characterization of the unknown sequence with the mathematical characterization of DNA sequences of known genera and species. The clinical identification of infectious organisms is required for accurate diagnosis and selection of antimicrobial therapeutics. The invention allows an ab initio approach with the potential for rapid identification of biological materials of unknown origin. The approach provides for identification and classification of emergent or new organisms without previous phenotypic identification. The technique may also be used in monitoring situations where the need exists for classification of material into broad categories of bacteria which could have an immediate impact on bio-terrorism prevention.