Jonathan Zalevsky - Riverside CA, US Duc-Hanh Thi Nguyen - Sylmar CA, US Gregory L. Moore - Monrovia CA, US Sergei A. Ezhevsky - San Diego CA, US John R. Desjarlais - Pasadena CA, US Arthur J. Chirino - Camarillo CA, US Darian Cash - Los Angeles CA, US Matthew J. Bernett - Monrovia CA, US
An adiponectin variant with one or more amino acid modifications relative to a corresponding parent adiponectin, wherein the adiponectin variant is not glycosylated, the adiponectin variant does not have residues 1-100 relative to human adiponectin, and wherein the solubility of the variant is improved by at least 3-fold relative to residues 110-244 of human adiponectin.
John R. Desjarlais - Pasadena CA, US Jonathan Zalevsky - Riverside CA, US Gregory L. Moore - Pasadena CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
G06F 19/00
US Classification:
702 27
Abstract:
The present invention relates to the use of simulation technology to rationally optimize the locations and sizes of attached polymeric moieties for modification of therapeutic proteins and the proteins generated from this method.
Pharmaceutical Compositions Of Adiponectin Variants And Methods Of Storage
Jonathan Zalevsky - Riverside CA, US Duc-Hanh Thi Nguyen - Sylmar CA, US Gregory L. Moore - Monrovia CA, US Sergei A. Ezhevsky - San Diego CA, US John R. Desjarlais - Pasadena CA, US Arthur J. Chirino - Camarillo CA, US Darian Cash - Los Angeles CA, US Matthew J. Bernett - Monrovia CA, US
A composition comprising an adiponectin variant at a concentration of at least 2. 0 mg/mL, and a pharmaceutically acceptable carrier, wherein less than 20% of said adiponectin variant would aggregate after storage at 4 C. for one week in 10 mM PO, 150 mM NaCl buffer.
Jonathan Zalevsky - Riverside CA, US Duc-Hanh Thi Nguyen - Sylmar CA, US Gregory L. Moore - Monrovia CA, US Sergei A. Ezhevsky - San Diego CA, US John R. Desjarlais - Pasadena CA, US Arthur J. Chirino - Camarillo CA, US Darian Cash - Los Angeles CA, US Matthew J. Bernett - Monrovia CA, US
An adiponectin variant with one or more amino acid modifications relative to a corresponding parent adiponectin, wherein the solubility of the variant is improved by at least 3-fold relative to residues 110-244 of human adiponectin.
Jonathan Zalevsky - Riverside CA, US Duc-Hanh Thi Nguyen - Sylmar CA, US Gregory L. Moore - Monrovia CA, US Sergei A. Ezhevsky - San Diego CA, US John R. Desjarlais - Pasadena CA, US Arthur J. Chirino - Camarillo CA, US Darian Cash - Los Angeles CA, US Matthew J. Bernett - Monrovia CA, US
Assignee:
Xencor, Inc. - Monrovia CA
International Classification:
A01N 37/18 A61K 38/16 A61K 38/00
US Classification:
514 2, 514 8, 514 21
Abstract:
A method of treating a mammal with an adiponectin mediated disorder comprising administering a therapeutically effective amount of an adiponectin variant with at least a 3-fold increased solubility relative to residues 110-244 of human adiponectin.
Aaron Chamberlain - Pasadena CA, US John Desjarlais - Pasadena CA, US Gregory Moore - Pasadena CA, US
International Classification:
A61K038/17 C07K014/74
US Classification:
514012000, 530350000
Abstract:
The present invention relates to soluble, recombinant CD40L variant proteins that may be expressed solubly in . The variants of the present invention may substantially reduced binding to alpha IIb-beta3 integrin, act as CD40L antagonists or agonists, and methods for generating the same.
Methods For The Design Of Libraries Of Protein Variants
Gregory Moore - Saugus CA, US John Rahn - West Hills CA, US
International Classification:
H01L 21/00
US Classification:
438031000
Abstract:
An apparatus in one example has an integrated optic component having at least a higher order mode energy and a lower order mode energy. The integrated optic component also has a portion with a predetermined configuration such that radiation divergence losses of the higher order mode energy being much larger than radiation divergence losses of the lower order mode energy.
Name / Title
Company / Classification
Phones & Addresses
Gregory S Moore President BOD
Greater Lake City Chamber of Commerce Chambers Of Commerce
PO Box 669, 144 South Acline Ave, Lake City, SC 29560-0669 843 374-8611
Gregory Moore Owner
Discount Cabinet Source Furniture Stores
20885 Golden Springs Dr, Walnut, CA 91789 Website: dcscabinets.com
Gregory Moore Owner
The Oystercatcher Eating Places
2225 S. Castle Harbour Place, Ontario, CA 91761
Gregory Moore Vice President
Montgomery West Miscellaneous Apparel and Accessory Stores
110 E 9Th St Ste A1083, Los Angeles, CA 90079
Gregory Moore President
MoeBiz Investment Advice
13547 Ventura Blvd #679, Van Nuys, CA 91423
Gregory Moore Product Manager
Compumed, Inc. Computer Integrated Systems Design
5777 W Century Blvd, Los Angeles, CA 90045
Gregory Glenn Moore Director
Glenn Moore Softball Camps Inc
Gregory Moore Director
Greater New Hope Mission Church Religious Organization
177 E 6 St, Perris, CA 92570 PO Box 1409, Perris, CA 92572 951 657-1271
Corridor Primary Care PedsCorridor Primary Care Internal Medicine 601A Leah Ave, San Marcos, TX 78666 512 396-1000 (phone)
Education:
Medical School Baylor College of Medicine Graduated: 1983
Procedures:
Cardiac Stress Test Continuous EKG Destruction of Benign/Premalignant Skin Lesions Electrocardiogram (EKG or ECG) Pulmonary Function Tests Vaccine Administration
Dr. Moore graduated from the Baylor College of Medicine in 1983. He works in San Marcos, TX and specializes in Internal Medicine. Dr. Moore is affiliated with Central Texas Medical Center.
James River Obstetrics & Gynecology 7101 Jahnke Rd STE 280, Richmond, VA 23225 804 272-5508 (phone), 804 323-7564 (fax)
Education:
Medical School Virginia Commonwealth University SOM Graduated: 1990
Procedures:
D & C Dilation and Curettage Hysterectomy Myomectomy Ovarian Surgery Tubal Surgery Vaginal Repair
Conditions:
Abnormal Vaginal Bleeding Breast Disorders Candidiasis of Vulva and Vagina Complicating Pregnancy or Childbirth Conditions of Pregnancy and Delivery
Languages:
English Spanish
Description:
Dr. Moore graduated from the Virginia Commonwealth University SOM in 1990. He works in Richmond, VA and specializes in Obstetrics & Gynecology. Dr. Moore is affiliated with Chippenham Hospital.
Dr. Moore graduated from the University of California, San Francisco School of Medicine in 1983. He works in Manteca, CA and specializes in Emergency Medicine. Dr. Moore is affiliated with Doctors Hospital Of Manteca.
Pinnacle Anesthesia ConsultantsSouth West Orthopedics 6311 Southwest Blvd, Fort Worth, TX 76132 817 731-2795 (phone), 817 731-4282 (fax)
Education:
Medical School West Virginia College of Osteopathic Medicine Graduated: 2003
Procedures:
Carpal Tunnel Decompression Hip/Femur Fractures and Dislocations Lower Arm/Elbow/Wrist Fractures and Dislocations Lower Leg/Ankle Fractures and Dislocations Shoulder Arthroscopy Shoulder Surgery Arthrocentesis Hallux Valgus Repair Hip Replacement Joint Arthroscopy Knee Arthroscopy Knee Replacement
Conditions:
Fractures, Dislocations, Derangement, and Sprains Lateral Epicondylitis Hallux Valgus Internal Derangement of Knee Internal Derangement of Knee Cartilage
Languages:
English Spanish
Description:
Dr. Moore graduated from the West Virginia College of Osteopathic Medicine in 2003. He works in Fort Worth, TX and specializes in Orthopaedic Surgery and Orthopedic Sports Medicine. Dr. Moore is affiliated with Plaza Medical Center Of Fort Worth and USMD Hospital At Fort Worth.
Stamps Health Services 740 Ferst Dr, Atlanta, GA 30332 404 894-1420 (phone), 404 385-3826 (fax)
Education:
Medical School Uniformed Services University of the Health Sciences Hebert School of Medicine Graduated: 1983
Conditions:
Polycystic Ovarian Syndrome (PCOS) Abnormal Vaginal Bleeding Breast Disorders Candidiasis of Vulva and Vagina Conditions of Pregnancy and Delivery
Languages:
English
Description:
Dr. Moore II graduated from the Uniformed Services University of the Health Sciences Hebert School of Medicine in 1983. He works in Atlanta, GA and specializes in Gynecology. Dr. Moore II is affiliated with Piedmont Atlanta Hospital.
Neurology Spine Institute 74B Centennial Loop STE 100, Eugene, OR 97401 541 686-3791 (phone), 541 686-3795 (fax)
Two River Surgical Center 74B Centennial Loop STE 200, Eugene, OR 97401 541 393-0925 (phone), 541 393-0914 (fax)
Education:
Medical School University of Texas Medical School at San Antonio Graduated: 2003
Languages:
English Spanish
Description:
Dr. Moore graduated from the University of Texas Medical School at San Antonio in 2003. He works in Eugene, OR and 1 other location and specializes in Pain Management. Dr. Moore is affiliated with Mckenzie Willamette Medical Center and Peacehealth Sacred Heart Medical Center Hospital.
Deaconess Hospital Emergency Medicine 600 Mary St, Evansville, IN 47710 812 450-7299 (phone), 812 450-3099 (fax)
Education:
Medical School Indiana University School of Medicine Graduated: 1981
Languages:
English
Description:
Dr. Moore graduated from the Indiana University School of Medicine in 1981. He works in Evansville, IN and specializes in Emergency Medicine. Dr. Moore is affiliated with Deaconess Gateway Hospital and Deaconess Hospital.
Western Carolina University, B.S., 1994; Western Carolina University, M.A., 1998; University of Denver, Graduate School of International Studies, M.A., 2008
Law School:
University of Denver, J.D., 2007; MA University of Denver Josef Korbel School of International Studies, 2008; University of Denver, Sturm College of Law, J.D., 2007
Office Depot Issaquah, WA Jun 2013 to Nov 2013 Department MangerWDS Global Redmond, WA Jul 2012 to May 2013 Customer Experience SpecialistStaples Superstore Redmond, WA Jul 2010 to Jul 2012 Copy & Print ManagerStaples Copy & Print Shop Los Angeles, CA Jan 2010 to Jul 2010 Sales Associate
EXTENDING FAMILIES CARE CONSORTIUM Los Angeles, CA 2006 to 2009 Assisted Living Project Pilot Program CoordinatorCOMPUMED, Incorporated Los Angeles, CA 2002 to 2006 Operations Manager, Electrocardiogram (ECG)ECG
2001 to 2002 Laboratory SupervisorECG
2000 to 2001 Technician
Education:
CHARLES DREW UNIVERSITY Compton, CA Jan 2010 to Jan 2011 Certified Phlebotomy TechnicianEL CAMINO COLLEGE Compton, CA Certificate in Certified Nursing AssistantASSOCIATED TECHNICAL COLLEGE Los Angeles, CA Medical Assistant/Cardiac Technician
Dec 2011 to 2000 Aquatics SupervisorNational Everclean Agoura Hills, CA Nov 2010 to Nov 2011 Food Safety AuditorThe Food Tutor Lancaster, TX Jan 2009 to Nov 2010 Food Safety ConsultantThe City of Arlington Arlington, TX Apr 2000 to Jan 2009 Environmental Health SpecialistThe City of Dallas Dallas, TX Aug 1995 to Apr 2000 SanitarianPresbyterian Hospital Dallas, TX Aug 1991 to Apr 1995 Restaurant Manager
Education:
Grambling State University 1989 Bachelor of Science in Management
Skills:
Licensed pesticide applicator ,Food safety professional, Pool Operations Manager (City of Dallas)
Aug 2009 to 2000 Licensed Sales RepVector Temecula, CA Jun 2008 to Nov 2009 Field Sales RepNexcycle Hemet, CA Feb 2003 to Jun 2008 Managing Site Attendant
Education:
Eisenhower High School Rialto, CA Jun 2001 Diploma
Gregory Moore or Greg Moore is the name of: Gregory L. Moore, American journalist and editor of the Denver Post; Greg Moore (racing driver) (19751999), ...
Gregory Moore faced up to three yearsin prison after he pleaded guilty to felony inducing panic and misdemeanor falsification charges for the phony statements and unrelated bomb threatsMoore called in to courthouses to avoid hearings in other cases.
Date: May 23, 2017
Category: U.S.
Source: Google
SIAC suspends 15 players following brawl during hoop game (Jan 20, 2017)
The interests of student-athlete and spectator safety and good sportsmanship during intercollegiate athletic events are sacrosanct and represent a core article of faith for our league, SIAC commissioner Gregory Moore said in a statement. The incident which unfolded Saturday evening not only was i
Date: Jan 20, 2017
Category: Sports
Source: Google
Crews Continue Search For Man Missing After Boat Capsizes
year-old Jason Downing of Mechanicsville, was found clinging to the hull of the boat. Downing was taken to a hospital, but police didnt have details of his condition. They say 55-year-old Gregory Moore of Mechanicsville and 48-year-old William Edelen Jr. of White Plains were found dead on Sunday. A
Date: Nov 21, 2016
Category: U.S.
Source: Google
One fisherman found on hull, two dead after Potomac boat incident on windy weekend
Police identified the survivor as Jason Downing, 39, of Mechanicsville, and said he was taken to MedStar St. Mary's Hospital in unknown condition. The two deceased victims were Gregory Moore, 55, of Mechanicsville, the owner of the boat; and William Edelen Jr., 48, of White Plains. Natural Resources
Date: Nov 20, 2016
Category: U.S.
Source: Google
New E-ZPass center opens, may help ease hard times downtown
We recycled an aging building that needed a lot of help, DDP president Gregory Moore said. We now have thriving business there and it will help our community. That building had been closed for about six to eight years. It was in demise and we injected some new money into it, and now we have new e
Date: Mar 10, 2014
Category: Business
Source: Google
Study finds youngest preemies at significant risk of neurodevelopmental problems
Lead author Dr. Gregory Moore of the Childrens Hospital of Eastern Ontario says he and his colleagues did the study in order to have better information to give parents who want to know what their child might experience.
Date: Aug 26, 2013
Category: Health
Source: Google
Study of antidepressants in pregnant women finds more risks than benefits
"I would say the authors of this article went overboard in terms of their negativity," Gregory Moore, director of health services at Georgia Tech in Atlanta and a member of the American College of Obstetricians and Gynecologists' committee on ethics, told USA Today. "Depression can be a fatal diseas
House policy advisor Gregory Moore said Wednesday that the state's move toward managed care in its Medicaid program will help providers. Once managed-care companies are selected, they will negotiate contracts with hospitals, clinics and doctors, beginning July 1.