Zuzana Dostalova

Scientist

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Location:

Cambridge, MA

Industry:

Hospital & Health Care

Work:

Eisai Research Institute
Scientist
Abpro
Scientist, Team Leader, Protein Purification
Harvard University Aug 2005 - Jun 2011
Postdoctoral Research Scientist
Millenium Research Laboratory 2010 - 2010
Bioanalytical Consultant
Uthscsa 1999 - 2004
Postdoctoral Fellow

Education:

Leibniz Universität Hannover 1993 - 1998
Doctorates, Doctor of Philosophy, Biochemistry Charles University
Master of Science, Masters, Bachelors, Bachelor of Science, Chemistry

Skills:

Membrane Protein Purification and Functional Reconstitution

Languages:

English
German
Czech
French
Russian

Zuzana Dostalova Cambridge, MA

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Work:

Eisai Pharmaceuticals

May 2013 to 2000
Research Scientist Abpro Corporation
Lexington, MA
2011 to 2013
Research Scientist MGH, Harvard Medical School
Boston, MA
2005 to 2011
Postdoctoral Fellow and Research Scientist

Education:

University Hannover
1993 to 1998
Ph.D. in sperm-egg recognition and a role of carbohydrates Charles University
Praha
1993
M.Sc. in Biochemistry Charles University
Praha
1991
B.Sc. in Biochemistry

Skills:

Production of recombinant proteins

Zuzana Dostalova Cambridge, MA

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Work:

Abpro Corporation

2011 to 2000
Research Scientist Massachusetts General Hospital, Harvard Medical School
Boston, MA
2005 to 2011
Postdoctoral Scientist Millennium Research Laboratories
Boston, MA
2010 to 2010
Bioanalytical Consultant UTHSC
San Antonio, TX
1999 to 2004
Postdoctoral Fellow

Education:

University Hannover
Germany
1993 to 1998
Ph.D. in Biochemistry Thesis title: Purification and functional characterization of lectin-like proteins involved in sperm-egg recognition and a role of carbohydrates in cell-cell interaction Charles University
Praha
1993
M.Sc. in Biochemistry Charles University
Praha
1991
B.Sc. in Biochemistry

Skills:

Expertise in membrane protein expression, purification and functional reconstitution into lipids. Six years of experience with neurotransmitter-gated ion channels (GABAA and serotonin receptors) leading to identification of receptor drug binding sites. Two years of industrial experience as a team leader of protein purification unit at Abpro; utilizing high throughput screening and scale-up production, purified hundreds of recombinant proteins, secreted, cytoplasmic, and membrane proteins for antibody production and sale. Technical expertise in protein expression in a variety of hosts, primarily insect cells and mammalian cell lines on plates and scale up to 10L using a Bioreactor. More than ten years of experience with classical chromatographic methods and protein chemistry techniques: FPLC and HPLC (AKTA purifier), SDS-PAGE, Western Blotting, and Capillary electrophoresis (Calliper). As a bioanalytical consultant for Millenium Research Laboratories developed and validated enzyme linked immunosorbent assay (ELISA). Design, analyze, and conduct experiments independently. Critical thinker, strong team player focusing on teams mutual success.