Zishan A Haroon

US Patent:

7598057, Oct 6, 2009

Filed:

Aug 30, 2006

Appl. No.:

11/512501

Inventors:

Murat O. Arcasoy - Chapel Hill NC, US
Zishan A. Haroon - Ironwood MI, US

Assignee:

Duke University - Durham NC

International Classification:

C12N 15/00
C07H 21/04
C07K 14/00

US Classification:

435 691, 536 231, 536 243, 530350

Abstract:

Nucleic acids encoding erythropoietin receptor isoforms are described, as well as the encoded isoforms, methods of detecting the same, and methods of screening for and treating cancer.

US Patent:

8273551, Sep 25, 2012

Filed:

Jun 27, 2011

Appl. No.:

13/169641

Inventors:

Murat O. Arcasoy - Chapel Hill NC, US
Zishan A. Haroon - Ironwood MI, US

Assignee:

Duke University - Durham NC

International Classification:

C12N 15/00
C07H 21/04
C07K 14/00

US Classification:

435 691, 536 235, 530350

Abstract:

Nucleic acids encoding erythropoietin receptor isoforms are described, as well as the encoded isoforms, methods of detecting the same, and methods of screening for and treating cancer.

US Patent:

8617844, Dec 31, 2013

Filed:

Aug 27, 2012

Appl. No.:

13/595436

Inventors:

Murat O. Arcasoy - Chapel Hill NC, US
Zishan A. Haroon - Ironwood MI, US

Assignee:

Duke University - Durham NC

International Classification:

C12N 15/09
C12N 15/12
C07H 21/02
C07H 21/04

US Classification:

435 691, 536 231, 536 235

Abstract:

Nucleic acids encoding erythropoietin receptor isoforms are described, as well as the encoded isoforms, methods of detecting the same, and methods of screening for and treating cancer.

US Patent:

20040043462, Mar 4, 2004

Filed:

Sep 2, 2003

Appl. No.:

10/416603

Inventors:

Zishan Haroon - San Francisco CA, US
Charles Greenberg - San Francisco CA, US
Mark Dewhirst - Durham NC, US

International Classification:

C12N005/00
C12M001/00

US Classification:

435/183000, 435/283100, 435/029000, 435/375000

Abstract:

A chamber for in vivo delivery of an active agent, the chamber including a housing having at least two porous surfaces, the at least two porous surfaces disposed on substantially opposite sides of the housing from each other; an internal void space within the housing; and a matrix composition comprising an active agent, the matrix composition disposed within the internal void space. Therapeutic and screening methods employing the chamber are also disclosed, including methods for in vivo screening of angiogenesis and/or tumor growth modulating agents.

US Patent:

20040197873, Oct 7, 2004

Filed:

Jul 23, 2003

Appl. No.:

10/625137

Inventors:

Murat Arcasoy - Chapel Hill NC, US
Zishan Haroon - Ironwood MI, US

International Classification:

C07K014/505
C07H021/04

US Classification:

435/069400, 435/320100, 435/325000, 530/399000, 536/023500

Abstract:

Nucleic acids encoding erythropoietin isoforms are described herein, as well as the encoded isoforms, methods of detecting the same, and methods of screening for and treating cancer.

US Patent:

20090074672, Mar 19, 2009

Filed:

Sep 17, 2008

Appl. No.:

12/212646

Inventors:

Gregory W. Faris - Menlo Park CA, US
Chia-Pin Pan - Menlo Park CA, US
Zishan Haroon - Chadds Ford PA, US

International Classification:

A61K 49/00

US Classification:

424 96

Abstract:

Tumor boundaries and wound healing are optically imaged by cross-linking a fluorescently-labeled tissue transglutaminase substrate into extracellular matrix.

US Patent:

20100092975, Apr 15, 2010

Filed:

Aug 17, 2009

Appl. No.:

12/542229

Inventors:

Murat O. Arcasoy - Chapel Hill NC, US
Zishan A. Haroon - Ironwood MI, US

International Classification:

C12Q 1/68
C07H 21/00
C12N 15/74
C12N 5/071
C07K 14/00
C07K 16/00
C07H 21/04
G01N 33/53

US Classification:

435 6, 536 235, 4353201, 435325, 530350, 5303871, 536 2431, 435 721, 435 79

Abstract:

Nucleic acids encoding erythropoietin isoforms are described herein, as well as the encoded isoforms, methods of detecting the same, and methods of screening for and treating cancer.

US Patent:

20120022012, Jan 26, 2012

Filed:

Jul 14, 2011

Appl. No.:

13/183222

Inventors:

Brian Shull - Durham NC, US
John Baldwin - Gwynedd PA, US
Ramesh Gopalaswamy - Cary NC, US
Zishan Haroon - Chapel Hill NC, US

International Classification:

A61K 31/7036
A61P 25/04
C07H 15/22

US Classification:

514 35, 536 179

Abstract:

The present invention relates to methods and compositions for the synthesis, production, and use of pro-drug analogs of the analgesic acetaminophen. This invention relates to a method for the production of a broad group of glycosides of acetaminophen derivatives.