Yolonda L Colson

US Patent:

8334324, Dec 18, 2012

Filed:

Jan 20, 2010

Appl. No.:

12/690607

Inventors:

Yolonda L. Colson - Dover MA, US
Solomon Azouz - Dallas TX, US
Mark W. Grinstaff - Brookline MA, US
Jesse Wolinsky - Brookline MA, US
Aaron Griset - Medford MA, US

Assignee:

The Trustees of the Boston University - Boston MA
The Brigham and Women's Hospital, Inc. - Boston MA

International Classification:

A61K 47/06

US Classification:

5147723

Abstract:

Described herein are compounds and processes that can be used to prepare polymer-based films, particles, gels and related compositions, and processes for delivery of agents, and other uses.

US Patent:

8338492, Dec 25, 2012

Filed:

Jun 18, 2010

Appl. No.:

12/818693

Inventors:

Yolonda L. Colson - Dover MA, US
Solomon Azouz - Dallas TX, US
Mark W. Grinstaff - Brookline MA, US
Jesse Wolinsky - Brookline MA, US
Aaron Griset - Medford MA, US

Assignee:

The Trustees of the Boston University - Boston MA
The Brigham and Women's Hospital, Inc. - Boston MA

International Classification:

A61K 47/06

US Classification:

5147723

Abstract:

Described herein are compounds and processes that can be used to prepare polymer-based films, particles, gels and related compositions, and processes for delivery of agents, and other uses.

US Patent:

20040142855, Jul 22, 2004

Filed:

Feb 27, 2003

Appl. No.:

10/375376

Inventors:

Yolonda Colson - Needham MA, US
Matthew Schuchert - Pittsburgh PA, US

Assignee:

University of Pittsburgh

International Classification:

A61K038/17
C07K014/47

US Classification:

514/008000, 530/395000

Abstract:

The present invention relates to the isolation and identification of cellular proteins and protein complexes that promote the engraftment of allogeneic stem cells and the induction of immunologic tolerance in recipient transplant hosts. More specifically, the present invention relates to a novel 33 kD glycoprotein, p33, that can form a complex with the T cell receptor (TCR) chain, alone or in association with the CD3 antigen. The presence of the p33 protein, the TCR/p33 complex or the CD3/TCR/p33 complex of the invention on the surface of cells correlates with the ability of those cells to facilitate allogeneic engraftment in vivo. The compositions and methods of this invention are useful for promoting the engraftment of allogeneic cells and tissues in vivo, for the reduction of Graft Versus Host Disease (GVHD) which occurs in connection with transplantation of allogeneic cells in vivo and for the induction of immunologic tolerance to donor cells and tissue in vivo, e.g., in solid organ or tissue transplantation or in bone marrow transplantation used in connection with the treatment of leukemia or other hematological diseases.

US Patent:

20080075718, Mar 27, 2008

Filed:

May 31, 2007

Appl. No.:

11/756587

Inventors:

Yolonda Colson - Needham MA, US
Solomon Azouz - San Antonio TX, US
Mark Grinstaff - Brookline MA, US
Jesse Wolinsky - Brookline MA, US
Aaron Griset - Brookline MA, US

International Classification:

A61K 39/395
A61K 31/131
A61K 31/135
A61K 31/164
A61K 31/17
A61K 31/192
A61K 31/28
A61K 31/336
A61K 31/337
A61K 31/35
A61K 31/357
A61K 31/407
A61K 31/4164
A61K 31/445
A61K 31/496
A61K 31/4985
A61K 31/505
A61K 31/52
C08G 75/26
C08G 63/08
C07D 313/04
A61K 31/551
A61K 31/65
A61K 31/66
A61K 38/08
A61K 38/50

US Classification:

424133100, 424094600, 514110000, 514015000, 514152000, 514183000, 514215000, 514249000, 514252110, 514256000, 514263230, 514263300, 514274000, 514316000, 514398000, 514413000, 514449000, 514452000, 514459000, 514492000, 514567000, 514588000, 514589000, 514620000, 514653000, 514672000, 514748000, 528354000, 528380000, 549271000

Abstract:

Described herein are compounds and processes that can be used to prepare polymer-based films, particles, gels and related compositions, and processes for delivery of agents, and other uses.

US Patent:

20110172785, Jul 14, 2011

Filed:

May 7, 2009

Appl. No.:

12/991944

Inventors:

Jesse Wolinsky - Brookline MA, US
Mark W. Grinstaff - Brookline MA, US
Yolonda L. Colson - Dover MA, US

Assignee:

THE TRUSTEES OF BOSTON UNIVERSITY - Boston MA
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. - Boston MA

International Classification:

A61F 2/02
B05D 7/00

US Classification:

623 2372, 427 224

Abstract:

A compliant composite for delivering a bioactive agent including a scaffolding material and a polymer coating that together can be attached to compliant tissue surfaces is disclosed, along with methods for constructing and applying these composites. In some embodiments, the composite further comprises a barrier layer for localized delivery of the bioactive agent.

US Patent:

20230114205, Apr 13, 2023

Filed:

Oct 7, 2022

Appl. No.:

17/962149

Inventors:

- Boston MA, US
Yolonda Colson - Dover MA, US
Mark W. Grinstaff - Brookline MA, US
Wilson Wai Chun Wong - Brookline MA, US

Assignee:

Trustees of Boston University - Boston MA
The General Hospital Corporation - Boston MA

International Classification:

A61K 9/70
A61K 47/36
A61K 47/34
A61K 47/64
A61K 47/10

Abstract:

The present disclosure generally relates to compositions and method for delivery, e.g., sustained delivery of active agents, and their use for the treatment of diseases or disorders.

US Patent:

20210259794, Aug 26, 2021

Filed:

Feb 18, 2021

Appl. No.:

17/179153

Inventors:

- Melvile NY, US
- Boston MA, US
Brian Ninni - Brighton MA, US
Charles George Hwang - Boston MA, US
Yolonda Lorig Colson - Dover MA, US
Hisashi Tsukada - Boston MA, US

International Classification:

A61B 34/00
A61B 17/00

Abstract:

An articulated medical device having a hollow core, capable of large degrees of maneuverability through small cavities to reach a target with minimal invasiveness, wherein the medical device is capable of manual and robotic manipulation.

US Patent:

20140271489, Sep 18, 2014

Filed:

Oct 17, 2012

Appl. No.:

14/351972

Inventors:

- Boston MA, US
Yolonda Colson - Dover MA, US

Assignee:

TRUSTEES OF BOSTON UNIVERSITY - Boston MA

International Classification:

A61K 9/16
A61K 31/519
A61K 31/352
A61K 31/337
A61K 49/00

US Classification:

424 96, 514449, 424489, 514453, 5142651

Abstract:

Provided herein are polymeric particles and compounds and processes that can be used to prepare polymer-based particles and methods of using those particles to localize or concentrate a subsequently delivered agent to an in vivo site.