Xiaomei M Xu

US Patent:

6583277, Jun 24, 2003

Filed:

Jan 26, 2001

Appl. No.:

09/771467

Inventors:

Yuling Luo - South San Francisco CA
Xiaomei Xu - South San Francisco CA

Assignee:

Exelixis, Inc. - South San Francisco CA

International Classification:

C07H 2104

US Classification:

536 235, 536 231, 530300, 530327, 530324, 530350, 435 691

Abstract:

The invention provides methods and compositions relating to semaphorin K1 (sema K1) polypeptides which regulate cellular guidance and physiology, and related nucleic acids. The polypeptides may be produced recombinantly from transformed host cells from the disclosed sema K1 encoding nucleic acids or purified from human cells. The invention provides isolated sema K1 hybridization probes and primers capable of specifically hybridizing with the disclosed sema K1 genes, sema K1-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.

US Patent:

62252852, May 1, 2001

Filed:

Mar 11, 1998

Appl. No.:

9/041236

Inventors:

Yuling Luo - South San Francisco CA
Xiaomei Xu - South San Francisco CA

Assignee:

Exelixis Pharmaceuticals, Inc. - South San Francisco CA

International Classification:

A61K 3800
C07K 1400
C07K 1600
C07K 1700
C07K 500

US Classification:

514 12

Abstract:

The invention provides methods and compositions relating to semaphorin K1 (sema K1) polypeptides which regulate cellular guidance and physiology, and related nucleic acids. The polypeptides may be produced recombinantly from transformed host cells from the disclosed sema K1 encoding nucleic acids or purified from human cells. The invention provides isolated sema K1 hybridization probes and primers capable of specifically hybridizing with the disclosed sema K1 genes, sema K1-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.