William Wei

US Patent:

20040062787, Apr 1, 2004

Filed:

Aug 11, 2003

Appl. No.:

10/450344

Inventors:

William Daley - Morris Plains NJ, US
Randy Webb - Flemington NJ, US
Ann Comfort - New City NY, US
Santo Fleres - Hillsborough NJ, US
Alan Royce - Saylorsburg PA, US
William Wei - Belle Mead NJ, US

International Classification:

A61F002/00

US Classification:

424/423000

Abstract:

The present invention is directed to an improved sustained release drug delivery device comprising a drug core, a unitary cup, and a permeable plug.

US Patent:

20080287412, Nov 20, 2008

Filed:

Jul 28, 2008

Appl. No.:

12/180979

Inventors:

Ann R. Comfort - New City NY, US
William L. Daley - Morris Plains NJ, US
Santo J. Fleres - Hillsborough NJ, US
Alan E. Royce - Saylorsburg PA, US
Randy L. Webb - Flemington NJ, US
William S. Wei - Belle Mead NJ, US

International Classification:

A61K 31/55
B05D 3/02
A61P 9/12

US Classification:

51421007, 427 214

Abstract:

The present invention especially relates to the use of a combination comprising(1) an ACEI selected from the group consisting of benazepril, benazeprilat, and pharmaceutically acceptable salts thereof, and(2) amlodipine or pharmaceutically acceptable salt thereof,for the manufacture a medicament for the treatment or prevention or delay of progression of a condition selected from the group consisting of hypertension, congestive heart failure, angina, myocardial infarction, artherosclerosis, diabetic nephropathy, diabetic cardiac myopathy, renal insufficiency, peripheral vascular disease, left ventricular hypertrophy, cognitive dysfunction, blood pressure-related cerebrovasular disease, stroke, pulmonary disease or pulmonary hypertension and headache;wherein(i) the amount of amlodipine or a pharmaceutically acceptable salt thereof corresponds to 6 about mg to 40 about mg of the free base and(ii) the amount of the ACE inhibitor or a pharmaceutically thereof corresponds to 20 about mg to 160 about mg of benazepril hydrochloride.

US Patent:

20100196467, Aug 5, 2010

Filed:

Apr 16, 2010

Appl. No.:

12/761450

Inventors:

William Lionel Daley - Morris Plains NJ, US
Randy Lee Webb - Flemington NJ, US
Ann Reese Comfort - New City NY, US
Santo Joseph Fleres - Hillsborough NJ, US
Alan Edward Royce - Saylorsburg PA, US
William Shifeng Wei - Belle Mead NJ, US

International Classification:

A61K 31/55
A61K 9/48
A61K 9/66
A61P 9/12
B05D 3/00

US Classification:

424455, 51421207, 424456, 427 214

Abstract:

The present invention especially relates to the use of a combination comprising(1) an ACEI selected from the group consisting of benazepril, benazeprilat, and pharmaceutically acceptable salts thereof, and(2) amlodipine or pharmaceutically acceptable salt thereof, for the manufacture a medicament for the treatment or prevention or delay of progression of a condition selected from the group consisting of hypertension, congestive heart failure, angina, myocardial infarction, artherosclerosis, diabetic nephropathy, diabetic cardiac myopathy, renal insufficiency, peripheral vascular disease, left ventricular hypertrophy, cognitive dysfunction, blood pressure-related cerebrovasular disease, stroke, pulmonary disease or pulmonary hypertension and headache;wherein(i) the amount of amlodipine or a pharmaceutically acceptable salt thereof corresponds to 6 about mg to 40 about mg of the free base and(ii) the amount of the ACE inhibitor or a pharmaceutically thereof corresponds to 20 about mg to 160 about mg of benazepril hydrochloride.

Author:

William Wei

ISBN #:

0472100572

Author:

William Wei

ISBN #:

0782144357