William Dr Simmons

Author:

William T. Simmons

ISBN #:

0915442337

Author:

William S. Simmons

ISBN #:

0791003647

Author:

William S. Simmons

ISBN #:

0874512395

Author:

William Hayne Simmons

ISBN #:

0813004004

Author:

William P. Simmons

ISBN #:

1930997442

Author:

William P. Simmons

ISBN #:

1930997450

Author:

William P. Simmons

ISBN #:

9185075000

Author:

William J. Simmons

ISBN #:

0405018363

US Patent:

7390789, Jun 24, 2008

Filed:

Sep 13, 2005

Appl. No.:

11/225748

Inventors:

William H Simmons - Westchester IL, US

International Classification:

A61K 38/06

US Classification:

514 18, 530331

Abstract:

The present invention is directed to an α thio-containing compound that is capable of inhibiting the enzyme, membrane aminopeptidase P (mAPP or APP), whose natural substrate is bradykinin. The compound is useful as a pharmaceutical agent because by inhibiting bradykinin degradation, the compound allows bradykinin to exert its beneficial effects on the cardiovascular system, to improve renal function, and to improve glucose tolerance and insulin-sensitivity. The present invention is also directed to a pharmaceutical composition comprising the mAPP inhibitor of the present invention and a pharmaceutically acceptable carrier. In another aspect, the present invention is directed to a method of inhibiting bradykinin degradation in a mammalian patient, preferably human, in need of treatment comprising administering to the patient a therapeutically effective amount of an α thio-containing compound of the present invention. The method of the present invention also contemplates the further step of administering to the mammalian patient in need of treatment a therapeutically effective amount of an inhibitor of angiotensin converting enzyme (ACE).

US Patent:

7748326, Jul 6, 2010

Filed:

Jul 24, 2008

Appl. No.:

12/178702

Inventors:

William R. Simmons - Brighton MI, US
Eric Snyder - Sterling Heights MI, US

Assignee:

GM Global Technology Operations, Inc. - Detroit MI

International Classification:

B61B 3/00

US Classification:

104 91, 104 89, 104249

Abstract:

A docking station for a monorail carrier system is provided. The carrier system includes a trolley that is configured to repositionably support a payload, and is adapted for interactive movement along a transfer bridge. The docking station includes a receiver plate having a rail-side portion perpendicularly oriented with a first interface portion that has one or more magnets attached thereto. A clamp assembly is attached to the rail-side portion, and operates to fasten the receiver plate to the transfer bridge at a predetermined location. The docking station also includes a docking plate having a trolley-side portion configured to securely attach to the trolley, and a second interface portion perpendicularly oriented with the trolley-side portion. The second interface portion is configured to magnetically cooperate with the first interface portion and thereby temporarily suspend the trolley at the predetermined location.

US Patent:

49879260, Jan 29, 1991

Filed:

Feb 5, 1990

Appl. No.:

7/475227

Inventors:

William L. Simmons - Farmington Hills MI

International Classification:

F16K 2706
F16K 3152

US Classification:

1376254

Abstract:

A faucet having a cistern-type pump body with a handle mounted on its upper end, and linkage connected to a rotary mixing valve mounted beneath the pump body such that when the handle is raised, a mixture of hot and cold water is delivered through a conduit mounted in the pump spout.

Address:

6526 Brezza Marina Ct, Las Vegas, NV 89131

Phone:

909 945-1250

VIN:

2GNALPEK0C6142852

Make:

CHEVROLET

Model:

EQUINOX

Year:

2012