William L Nichols

US Patent:

6359011, Mar 19, 2002

Filed:

Sep 8, 1999

Appl. No.:

09/391739

Inventors:

William Stefan Bess - Edison NJ
William Michael Nichols - Fanwood NJ

Assignee:

Warner-Lambert Company - Morris Plains NJ

International Classification:

A61K 31135

US Classification:

514646, 424166

Abstract:

The instant invention makes impractical the use of sympathomimetic amine compositions in illicit drug production. More specifically, the preparation of methamphetamine from the disclosed pseudoephedrine hydrochloride formulations is inhibited. The present invention defines pharmaceutical compositions comprising a sympathomimetic amine salt and at least one combination inhibitor, the combination inhibitor which acts both to interfere with the isolation of the sympathomimetic amine from the composition and to interfere with the conversion of the sympathomimetic amine to another pharmacologically active compound. The contemplated compositions may also include reaction and separation inhibitors in any mixture to assure maximum protection against the use of the sympathomimetic amine-containing compositions for illegal drug manufacture. The presence of the combination, reaction and separation inhibitors does not significantly alter the release of the sympathomimetic amine from the composition.

US Patent:

20020082304, Jun 27, 2002

Filed:

Nov 20, 2001

Appl. No.:

09/996438

Inventors:

William Bess - Edison NJ, US
William Nichols - Fanwood NJ, US

International Classification:

A61K031/137
A61K009/14

US Classification:

514/646000, 424/487000

Abstract:

The instant invention makes impractical the use of sympathomimetic amine compositions in illicit drug production. More specifically, the preparation of methamphetamine from the disclosed pseudoephedrine hydrochloride formulations is inhibited. The present invention defines pharmaceutical compositions comprising a sympathomimetic amine salt and at least one combination inhibitor, the combination inhibitor which acts both to interfere with the isolation of the sympathomimetic amine from the composition and to interfere with the conversion of the sympathomimetic amine to another pharmacologically active compound. The contemplated compositions may also include reaction and separation inhibitors in any mixture to assure maximum protection against the use of the sympathomimetic amine-containing compositions for illegal drug manufacture. The presence of the combination, reaction and separation inhibitors does not significantly alter the release of the sympathomimetic amine from the composition.

US Patent:

20050256194, Nov 17, 2005

Filed:

Jul 20, 2005

Appl. No.:

11/186681

Inventors:

William Bess - Edison NJ, US
William Nichols - Fanwood NJ, US

International Classification:

A61K031/205

US Classification:

514554000

Abstract:

The instant invention makes impractical the use of sympathomimetic amine compositions in illicit drug production. More specifically, the preparation of methamphetamine from the disclosed pseudoephedrine hydrochloride formulations is inhibited. The present invention defines pharmaceutical compositions comprising a sympathomimetic amine salt and at least one combination inhibitor, the combination inhibitor which acts both to interfere with the isolation of the sympathomimetic amine from the composition and to interfere with the conversion of the sympathomimetic amine to another pharmacologically active compound. The contemplated compositions may also include reaction and separation inhibitors in any mixture to assure maximum protection against the use of the sympathomimetic amine-containing compositions for illegal drug manufacture. The presence of the combination, reaction and separation inhibitors does not significantly alter the release of the sympathomimetic amine from the composition.

US Patent:

20060141031, Jun 29, 2006

Filed:

Dec 16, 2005

Appl. No.:

11/303822

Inventors:

Dennis Nelson - Mountain Lakes NJ, US
William Nichols - Somerset NJ, US

International Classification:

A61K 9/20

US Classification:

424464000

Abstract:

The present invention relates to pharmaceutical compositions that disintegrate in the mouth and include at least one systemically active pharmaceutical ingredient in a therapeutically effective amount and at least one sensory cue agent in a sensory effective amount.

US Patent:

20060216268, Sep 28, 2006

Filed:

Jun 2, 2006

Appl. No.:

11/445967

Inventors:

William Bess - Edison NJ, US
William Nichols - Fanwood NJ, US

International Classification:

A61K 31/765
A61K 31/137

US Classification:

424078270, 514649000

Abstract:

The instant invention makes impractical the use of sympathomimetic amine compositions in illicit drug production. More specifically, the preparation of methamphetamine from the disclosed pseudoephedrine hydrochloride formulations is inhibited. The present invention defines pharmaceutical compositions comprising a sympathomimetic amine salt and at least one combination inhibitor, the combination inhibitor which acts both to interfere with the isolation of the sympathomimetic amine from the composition and to interfere with the conversion of the sympathomimetic amine to another pharmacologically active compound. The contemplated compositions may also include reaction and separation inhibitors in any mixture to assure maximum protection against the use of the sympathomimetic amine-containing compositions for illegal drug manufacture. The presence of the combination, reaction and separation inhibitors does not significantly alter the release of the sympathomimetic amine from the composition.

US Patent:

61990817, Mar 6, 2001

Filed:

Jun 30, 1998

Appl. No.:

9/107225

Inventors:

Dmitriy Meyerzon - Bellevue WA
William G. Nichols - Seattle WA

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G06F 1721

US Classification:

707513

Abstract:

A computer-based method and system for processing data obtained from documents retrieved from a computer network during a gathering project is disclosed. Plugging in modular active and consumer plug-ins into the gathering project configures the information processing capability of the gathering process that retrieves the documents. The gathering process retrieves a copy of an electronic document from a server connected to the computer network and returns a document data stream that includes the retrieved document's data and its "properties. " One or more active plug-ins plugged-in to the gathering process is used to add, delete or modify the properties in the document data stream based on the document's contents or properties. The modified document data stream is then passed to one or more consumer plug-ins that use the properties in the modified document data stream to process the document in some manner. An active plug-in can prevent any part of the document data stream from being forwarded to subsequent active or consumer plug-ins in the project.

Author:

William Patrick Nichols

ISBN #:

0804693838

Author:

William C. Nichols

ISBN #:

0471299677

Author:

William Nichols

ISBN #:

0155978616

Author:

William Nichols

ISBN #:

0801002060

Author:

William D. Nichols

ISBN #:

0607861037

Author:

William D. Nichols

ISBN #:

0607944927