Ming T. Tsuang - La Jolla CA, US Ian P. Everall - San Diego CA, US Stephen J. Glatt - San Diego CA, US William S. Kremen - Carlsbad CA, US
International Classification:
C12Q 1/68 C12Q 1/02 G06F 17/18
US Classification:
435 6, 435 29, 702179
Abstract:
Systems and methods provide a comprehensive high-throughput approach toward the sequential identification, prioritization, verification, and validation of etiologic factors in neuropsychiatric disorders, some of which can also be utilized as biomarkers for these illnesses. The systems and methods determine patterns of gene expression in various tissues from various samples under various experimental and non-experimental conditions, and uses the differences and similarities between the gene expression profiles observed under these conditions to delineate distinct gene expression profiles of risk and treatment of neuropsychiatric disorders.
Other co-authors on the paper are Tyler Bell, Teresa Warren, William Kremen, and Carol Franz of the University of California San Diego; and Michael Lyons, Rosemary Toomey and Richard Vandiver of Boston University.