Sheng Wu - San Gabriel CA, US Andrei Deev - Pasadena CA, US Steve L. Palm - Escondido CA, US Yongchun Tang - Walnut CA, US William A. Goddard - Pasadena CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
G01N 21/25
US Classification:
356416
Abstract:
A frequency modulated spectroscopy system, including a photo-detector, a band-pass filter to filter the output of the photo-detector, and a rectifier to demodulate. The band-pass filter has a relatively high Q factor. With the high Q factor band-pass filter and rectifier, a reference sinusoid is not required for demodulation, resulting in phase-insensitive spectroscopy. Other embodiments are described and claimed.
Margaret A. Ryan - Pasadena CA, US Margie L. Homer - Pasadena CA, US Adam Kisor - Pasadena CA, US April D. Jewell - Somerville MA, US Abhijit V. Shevade - Altadena CA, US Kenneth S. Manatt - Tujunga CA, US Charles Taylor - Claremont CA, US Mario Blanco - Temple City CA, US William A. Goddard - Pasadena CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
C08F 126/06
US Classification:
526263, 526265, 526346, 526347
Abstract:
Embodiments include a sensor comprising a co-polymer, the co-polymer comprising a first monomer and a second monomer. For some embodiments, the first monomer is poly-4-vinyl pyridine, and the second monomer is poly-4-vinyl pyridinium propylamine chloride. For some embodiments, the first monomer is polystyrene and the second monomer is poly-2-vinyl pyridinium propylamine chloride. For some embodiments, the first monomer is poly-4-vinyl pyridine, and the second monomer is poly-4-vinyl pyridinium benzylamine chloride. Other embodiments are described and claimed.
Nanowire Sensor, Sensor Array, And Method For Making The Same
Minhee Yun - La Crescenta CA, US Nosang Myung - Rosemead CA, US Richard Vasquez - Altadena CA, US Margie Homer - Pasadena CA, US Margaret Ryan - Pasadena CA, US Jean-Pierre Fleurial - Altadena CA, US Ratnakumar Bugga - Arcadia CA, US Daniel Choi - Los Angeles CA, US William Goddard - Pasadena CA, US Abhijit Shevade - Pasadena CA, US Mario Blanco - Temple City CA, US Tahir Cagin - Arcadia CA, US Wely Floriano - Pasadena CA, US
The present invention relates to a nanowire sensor and method for forming the same. More specifically, the nanowire sensor comprises at least one nanowire formed on a substrate, with a sensor receptor disposed on a surface of the nanowire, thereby forming a receptor-coated nanowire. The nanowire sensor can be arranged as a sensor sub-unit comprising a plurality of homogeneously receptor-coated nanowires. A plurality of sensor subunits can be formed to collectively comprise a nanowire sensor array. Each sensor subunit in the nanowire sensor array can be formed to sense a different stimulus, allowing a user to sense a plurality of stimuli. Additionally, each sensor subunit can be formed to sense the same stimuli through different aspects of the stimulus. The sensor array is fabricated through a variety of techniques, such as by creating nanopores on a substrate and electrodepositing nanowires within the nanopores.
Yushan Yan - Riverside CA, US Xin Wang - Singapore, SG Wenzhen Li - Riverside CA, US Mahesh Waje - Riverside CA, US Zhongwei Chen - Riverside CA, US William Goddard - Pasadena CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
H01M 4/02 H01M 4/36 H01M 4/92 H01M 8/00 B05D 5/12
US Classification:
429524, 429523, 429529, 429530, 429535, 427115
Abstract:
Novel proton exchange membrane fuel cells and direct methanol fuel cells with nanostructured components are configured with higher precious metal utilization rate at the electrodes, higher power density, and lower cost. To form a catalyst, platinum or platinum-ruthenium nanoparticles are deposited onto carbon-based materials, for example, single-walled, dual-walled, multi-walled and cup-stacked carbon nanotubes. The deposition process includes an ethylene glycol reduction method. Aligned arrays of these carbon nanomaterials are prepared by filtering the nanomaterials with ethanol. A membrane electrode assembly is formed by sandwiching the catalyst between a proton exchange membrane and a diffusion layer that form a first electrode. The second electrode may be formed using a conventional catalyst. The several layers of the MEA are hot pressed to form an integrated unit.
Margaret A. Ryan - Pasasdena CA, US Margie L. Homer - Pasadena CA, US Adam Kisor - Pasadena CA, US April D. Jewell - Somerville MA, US Abhijit V. Shevade - Altadena CA, US Kenneth S. Manatt - Tujunga CA, US Charles Taylor - Claremont CA, US Mario Blanco - Temple City CA, US William A. Goddard - Pasadena CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
C08F 26/06 C08F 126/06
US Classification:
526260, 526265
Abstract:
Embodiments include a sensor comprising a co-polymer, the co-polymer comprising a first monomer and a second monomer. For some embodiments, the first monomer is poly-4-vinyl pyridine, and the second monomer is poly-4-vinyl pyridinium propylamine chloride. For some embodiments, the first monomer is polystyrene and the second monomer is poly-2-vinyl pyridinium propylamine chloride. For some embodiments, the first monomer is poly-4-vinyl pyridine, and the second monomer is poly-4-vinyl pyridinium benzylamine chloride. Other embodiments are described and claimed.
System And Methods For Predicting Transmembrane Domains In Membrane Proteins And Mining The Genome For Recognizing G-Protein Coupled Receptors
Rene J. Trabanino - Los Angeles CA, US Nagarajan Vaidehi - Arcadia CA, US Spencer E. Hall - Tucson AZ, US William A. Goddard - Pasadena CA, US Wely Floriano - Pasadena CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
G01N 33/48 C12Q 1/68 G06G 7/58 G06F 7/60
US Classification:
702 19, 435 6, 702 20, 703 2, 703 11, 700 90
Abstract:
The invention provides computer-implemented methods and apparatus implementing a hierarchical protocol using multiscale molecular dynamics and molecular modeling methods to predict the presence of transmembrane regions in proteins, such as G-Protein Coupled Receptors (GPCR), and protein structural models generated according to the protocol. The protocol features a coarse grain sampling method, such as hydrophobicity analysis, to provide a fast and accurate procedure for predicting transmembrane regions. Methods and apparatus of the invention are useful to screen protein or polynucleotide databases for encoded proteins with transmembrane regions, such as GPCRs.
Functional Anchors Connecting Graphene-Like Carbon To Metal
William A. Goddard - Pasadena CA, US Weiqiao Deng - Pasadena CA, US Yuki Matsuda - Pasadena CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
H01L 21/4763
US Classification:
438618
Abstract:
Functional linkers or anchors interconnecting graphene-like carbon, such as nanotubes or graphite sheets, with a conducting material such as a metal, are shown, together with related structures, devices, methods and systems.
Methods And Apparatus For Predicting Ligand Binding Interactions
Computer-implemented methods and apparatus implement a hierarchy of molecular modeling techniques for predicting binding sites of ligands in proteins, designing new pharmaceuticals and understanding the interactions of proteins involved in microbial pathogens. The techniques employ a hierarchical strategy ranging from coarse grain to fine grain conformational search methods combined with hierarchical levels of accuracy in scoring functions.
Name / Title
Company / Classification
Phones & Addresses
William A. Goddard
Jpf Realty IV, LLC Investments
18101 Von Karman Ave, Irvine, CA 92612
William A. Goddard
JPF INVESTMENTS I, LLC Owning and Operating Thoroughbred Raceho · Investor
1850 N Central Ave #1160, Phoenix, AZ 85004 18500 Von Karman Ave #400, Irvine, CA 92612
William A. Goddard Manager
JPF I, LLC
18500 Von Karman Ave STE 400 , Irvine, CA 92612 1012 Marquez Pl SUITE 106 B , Santa Fe, NM 87501
ratification in 1787 and 1788, some antifederalist printers accused the Post Office of suppressing their publications and arguments against the Constitution. William Goddard, the mastermind of the 1774 "Constitutional Post," ominously suggested he would once again start his own postal system.