Wentao Zhang - Foster City CA, US Sebastian Johannes Reinhard Liehr - East Palo Alto CA, US Mark Douglas Velligan - Montara CA, US Natalia B. Dyatkina - Mountain View CA, US Janos Botyanszki - Cupertino CA, US Dong-Fang Shi - San Mateo CA, US Christopher Don Roberts - Belmont CA, US Alexander Khorlin - Mountain View CA, US Peter Harold Nelson - Los Altos CA, US Joseph Martin Muchowski - Sunnyvale CA, US
Assignee:
Genelabs Technologies, Inc. - Redwood City CA
International Classification:
A61K031/13
US Classification:
514579
Abstract:
The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.
Aromatic Compounds And Poly(Oxyalkylene) Containing Aromatic Compounds Possessing Antibacterial, Antifungal Or Antitumor Activity
Natalia B. Dyatkina - Mountain View CA, US Dong-Fang Shi - Fremont CA, US Christopher Don Roberts - Belmont CA, US Mark Douglas Velligan - Montara CA, US Sebastian Johannes Reinhard Liehr - East Palo Alto CA, US Janos Botyanszki - Fremont CA, US Wentao Zhang - Foster City CA, US Alexander Khorlin - Mountain View CA, US Peter Harold Nelson - Los Altos CA, US Joseph Martin Muchowski - Sunnyvale CA, US
Assignee:
Genelabs Technologies, Inc. - Redwood City CA
International Classification:
C07D 207/00 C07D 207/10 A01N 43/64 A61K 31/40
US Classification:
548400, 548541, 548557, 514359, 514408
Abstract:
The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I):.
Navigation Signal Receiver Trajectory Determination
Chi-Shin Wang - Half Moon Bay CA, US David Wang - Belmont CA, US Wentao Zhang - Mountain View CA, US Jun Mo - San Jose CA, US Lei Dong - Cupertino CA, US
Assignee:
SIRF Technology Holdihgs, Inc. - San Jose CA
International Classification:
G01S 3/14
US Classification:
34235702, 34235713
Abstract:
The present invention provides methods and systems that enable a mobile navigation receiver to accurately determine its trajectory with non-current ephemeris in stand-alone mode. In an embodiment, the receiver computes the position for the same location using non-current ephemeris and current ephemeris at different time instances. The receiver then determines a position correction by finding the difference between these two computed positions, and applies this correction to the trajectory generated with non-current ephemeris to obtain a more accurate trajectory. In another embodiment, the receiver computes an initial position of the receiver using non-current ephemeris and finds the difference between the computed initial position and an accurate approximation of the initial position. The receiver then shifts the subsequent receiver trajectory computed using non-current ephemeris by the difference to obtain a more accurate trajectory.
The invention provides methods of treating cancer with a compound which inhibits kinases, more specifically IGF1R and Abl, in combination with treatments(s) selected from surgery, radiation, monoclonal antibody, bone marrow or peripheral blood stem cell transplantation, and one or more chemotherapeutic agent(s).
Systems And Methods Of Communication In An Assisted Navigation System
Shaowei Han - Palo Alto CA, US Wentao Zhang - Cupertino CA, US
Assignee:
Sirf Technology, Inc. - San Jose CA
International Classification:
G01C 21/00 G01S 19/25
US Classification:
701400, 34235764, 34235766
Abstract:
Provided herein are methods and systems for efficient communication between a server and a client in an assisted navigation system. In one or more embodiments, the client, e. g. , a GPS receiver, receives a set of parameters for a satellite from the server via a wireless or wired connection. The set of parameters includes a force parameter, initial condition parameters and time correction coefficients for the satellite. The receiver uses the received parameters in a numerical integration to compute the position of the satellite at a desired time. The set of parameters needed for the integration is small compared to current methods which require sending more data to the client. Thus these parameters require less communication resources to transmit. To further reduce the amount of data that needs to be transmitted, reference parameters may be subtracted from the original parameters before transmission from the server. The receiver is able to reconstruct the original parameters from the received parameters and the identically computed reference parameters.
In embodiments of sync feedback for time to first fix (TTFF), satellite data signals are received from which a geographic position of a positioning-system device can be determined. The satellite data signals each include a time reference and ephemeris data that indicates an orbital position of a satellite. A sync feedback is generated that includes a time-free position fix determined from a satellite data signal before bit sync and/or frame sync of the satellite data signal are obtained. The sync feedback is then utilized as a feedback input to determine the bit sync and/or the frame sync of the satellite data signal.
Methods And Apparatus For Self-Assisting Positioning System
Wentao Zhang - Cupertino CA, US Victor Lin - Fremont CA, US
Assignee:
Marvell International Ltd. - Hamilton
International Classification:
G06F 15/00
US Classification:
702150
Abstract:
In a method of implementing a positioning system a buffer is configured to store a buffer record for each of a plurality of position fixes determined by the receiver and a database is configured to store a database record for each of the position fixes. Buffer records are accumulated, with each buffer record corresponding to one of the position fixes determined by the receiver. A first threshold position near an area in which a degradation event occurs is identified and recorded in a first database record. A second threshold position near the area is identified in a second database record. The second threshold position is indicated by one of the position fixes outside of the area and is proximate to a position at which the degradation event ends.
Systems And Methods Of Communication In An Assisted Navigation System
Shaowei Han - Palo Alto CA, US Wentao Zhang - Cupertino CA, US
Assignee:
CSR Technology, Inc. - Sunnyvale CA
International Classification:
G01C 21/00
US Classification:
701400, 34235764
Abstract:
Provided herein are methods and systems for efficient communication between a server and a client in an assisted navigation system. In one or more embodiments, the server transmits a set of parameters for a satellite to the client, e. g. , a GPS receiver, via a wireless or wired connection. The set of parameters includes a force parameter, initial condition parameters and time correction coefficients for the satellite. The receiver uses the received parameters in a numerical integration to compute the position of the satellite at a desired time. The set of parameters needed for the integration is small. To further reduce the amount of data transmitted, reference parameters may be subtracted from the original parameters before transmission from the server. The receiver is able to reconstruct the original parameters from the received parameters and the identically computed reference parameters. The parameters may be further compressed using data compression techniques.
Exelixis 2001 - Aug 2012
Senior Director
Quintara Discovery 2001 - Aug 2012
Founder and President
Genelabs Technologies 1999 - 2001
Staff Scientist
Uc Berkeley 1997 - 1999
Postdoc
Education:
University of Wisconsin - Madison 1993 - 1996
Doctorates, Doctor of Philosophy, Chemistry
Emory University 1991 - 1993
Master of Science, Masters, Chemistry
Peking University 1987 - 1991
Bachelors, Bachelor of Science, Chemistry
Skills:
Drug Discovery Assay Development Biochemistry High Throughput Screening In Vitro Biotechnology Protein Chemistry Adme Lc Ms Drug Development Biomarker Discovery Oncology Cancer Medicinal Chemistry Drug Design