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Ulrike Jung

age ~46

from Hayward, CA

Ulrike Jung Phones & Addresses

  • Hayward, CA
  • Sunnyvale, CA
  • 8778 Spectrum Center Blvd APT 101, San Diego, CA 92123
  • Duarte, CA
  • Berkeley, CA

Work

  • Company:
    Beckman research institute, city of hope national medical center, jj rossi lab - duarte, ca
    Jun 2010
  • Position:
    Postdoctoral research fellow

Education

  • School / High School:
    Max Planck Institute for Infection Biology- Berlin
    May 2010
  • Specialities:
    PhD in Molecular Biology & RNAi

Skills

7 years working on infectious diseases a... • primary cells and hematopoietic stem cel... • application and analysis of side effect/... • primary cells and hematopoietic stem cel... • RNAi • plasmids • therapeutic proteins). 8+ years work... • tuberculosis • Listeria) under varying safety requireme... • BLS2+ and BLS3). Broad spectrum of ... • ELISA • qRT-PCR etc). 6+ years analysis of l... • transgene expression • therapeutic effect analysis in short &am... • informatics experience (scripting in jav... • transgene vectors • and synthesized nucleic acids) with tech... • step-up etc) Experience in budgeting... • multi-year grant application. Traini... • statistics • application • and analysis of clinical studies. 9+... • acting as author & reviewer for peer...

Us Patents

  • Design Of Rnai Molecules With Non-Watson Crick Pairing Based On Artificial Mutation Consensus Sequences To Counter Escape Mutations

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  • US Patent:
    20130303589, Nov 14, 2013
  • Filed:
    Mar 15, 2013
  • Appl. No.:
    13/842977
  • Inventors:
    Ulrike Jung - Duarte CA, US
  • International Classification:
    C12N 15/113
  • US Classification:
    514 44 A, 536 245
  • Abstract:
    Universal RNA interference (RNAi) molecules having an inhibitory RNA sequence which binds a target pathologic RNA sequence are provided according to some embodiments. Such RNAi molecules bind the target pathologic RNA sequence via at least one non-Watson Crick paired base. In some embodiments, the target pathologic RNA sequence is a target viral RNA sequence derived from a human immunodeficiency HIV virus, a hepatitis B virus (HBV), a hepatitis C virus (HCV), or an influenza virus.
  • Design Of Nucleic Acid Binding Molecules With Non-Watson Crick And Non-Canonical Pairing Based On Artificial Mutation Consensus Sequences To Counter Escape Mutations

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  • US Patent:
    20170283802, Oct 5, 2017
  • Filed:
    Apr 7, 2017
  • Appl. No.:
    15/482399
  • Inventors:
    - Duarte CA, US
    Ulrike JUNG - Duarte CA, US
  • International Classification:
    C12N 15/113
    C12Q 1/70
  • Abstract:
    Universal nucleic acid binding molecules (e.g., antisense oligonucleotides or RNAi molecules) having an inhibitory or activating nucleic acid sequence which binds a receiving nucleic acid sequence (e.g., RNA or DNA) are provided. In some embodiments, the universal nucleic acid binding molecules bind the receiving nucleic acid sequence (e.g., RNA or DNA) via at least one non-Watson Crick or non-canonical paired base.
  • Design Of Nucleic Acid Binding Molecules With Non-Watson Crick And Non-Canonical Pairing Based On Artificial Mutation Consensus Sequences To Counter Escape Mutations

    view source
  • US Patent:
    20140378526, Dec 25, 2014
  • Filed:
    Jun 19, 2014
  • Appl. No.:
    14/309803
  • Inventors:
    - Duarte CA, US
    Ulrike JUNG - Duarte CA, US
  • International Classification:
    C12N 15/113
    C12Q 1/70
  • US Classification:
    514 44 A, 536 245, 536 231, 435 5, 506 9
  • Abstract:
    Universal nucleic acid binding molecules (e.g., antisense oligonucleotides or RNAi molecules) having an inhibitory or activating nucleic acid sequence which binds a receiving nucleic acid sequence (e.g., RNA or DNA) are provided. In some embodiments, the universal nucleic acid binding molecules bind the receiving nucleic acid sequence (e.g., RNA or DNA) via at least one non-Watson Crick or non-canonical paired base.

Resumes

Ulrike Jung Photo 1

Ulrike Jung Duarte, CA

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Work:
Beckman Research Institute, City Of Hope National Medical Center, JJ Rossi lab - Duarte, CA

Jun 2010 to 2000
Postdoctoral Research Fellow
Max-Planck-Institute for Infection Biology, SHE Kaufmann lab - Berlin, Germany

Nov 2005 to May 2010
Graduate Student
ERNST MORITZ ARNDT UNIVERSITY, C. Schutt lab - Greifswald, Germany

Oct 2003 to Feb 2005
Master Student
UNIVERSITY OF MASSACHUSETTS (UMASS), K Rock lab - Worcester, MA

Jul 2002 to Oct 2002
Trainee/Intern
Education:
Max Planck Institute for Infection Biology
Berlin
May 2010
PhD in Molecular Biology & RNAi
Ernst Moritz Arndt Universitaet
Greifswald
1999 to 2005
Master of Science in Human Biology
Skills:
7 years working on infectious diseases and cancer gene expression for candidate evaluation & gene therapy. 6+ years non-viral based genetic modification of cell lines, primary cells and hematopoietic stem cells 8 years si/sh/microRNAs design, application and analysis of side effect/pathway perturbation. 9 years genetic modification of highly different bacterial organisms. 6+ years lentiviral vector de novo design/optimization/transducti... of cell lines, primary cells and hematopoietic stem cells (4+ years for bone marrow transplant based gene therapy, RNAi, plasmids, therapeutic proteins). 8+ years working with infectious pathogens (HIV, tuberculosis, Listeria) under varying safety requirements (BSL2, BLS2+ and BLS3). Broad spectrum of molecular biology techniques (including multi-color flow, ELISA, qRT-PCR etc). 6+ years analysis of lentiviral vector & HIV replication, transgene expression, therapeutic effect analysis in short & long term experiments. 6+ years virus production & purification (small and large scale for in vitro and in vivo experiments). 7 years extensive experience with RNA/DNA/protein sequence analysis software CLC Workbench (including genomic data/NGS), informatics experience (scripting in javascript & C-like PAWN). 9+ years designing complex genetic constructs (plasmid, transgene vectors, and synthesized nucleic acids) with techniques including Gibson assembly & sophisticated PCR technology (fusion PCR, step-up etc) Experience in budgeting for in vitro and in vivo preclinical experiments as part of an in-human pilot study, multi-year grant application. Training in design, statistics, application, and analysis of clinical studies. 9+ years supervising and training students (up to 2; recently my 1st Master student graduated). 6+ years inventory control & large equipment negotiation for 20+ research team. Excellent written & oral communication as well as presentation skills (both English & German), acting as author & reviewer for peer review

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