Michael A. Evans - Palo Alto CA, US Denise Demarais - Los Gatos CA, US Dino De Cicco - Campbell CA, US Kelvin Ning - Palo Alto CA, US Alexander Khairkhahan - Palo Alto CA, US Tyler Jon Strang - Palo Alto CA, US
Assignee:
Bacchus Vascular inc. - Santa Clara CA
International Classification:
A61M 31/00
US Classification:
604508, 604509
Abstract:
Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, aspirate clot and fluid, and allow passage of a guidewire. Optionally, the catheter may also include a mechanical agitator for further disrupt clot in the presence of the thrombolytic agent. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.
Michael A. Evans - Palo Alto CA, US Denise Demarias - Los Gatos CA, US Dino De Cicco - Campbell CA, US Kelvin Ning - Palo Alto CA, US Alexander Khairkhahan - Palo Alto CA, US Tyler Jon Strang - Palo Alto CA, US
Assignee:
Tyco Healthcare Group LP - Mansfield MA
International Classification:
A61B 17/20
US Classification:
604 22, 60410101, 60410105, 606128
Abstract:
Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, aspirate clot and fluid, and allow passage of a guidewire. Optionally, the catheter may also include a mechanical agitator for further disrupt clot in the presence of the thrombolytic agent. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.
Michael A. Evans - Palo Alto CA, US Denise Demarais - Los Gatos CA, US Dino De Cicco - Campbell CA, US Kelvin Ning - Palo Alto CA, US Alexander Khairkhahan - Palo Alto CA, US Tyler Jon Strang - Palo Alto CA, US
Assignee:
Covidien LP - Mansfield MA
International Classification:
A61M 31/00
US Classification:
604508, 604 22, 60410101, 604509
Abstract:
Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, aspirate clot and fluid, and allow passage of a guidewire. Optionally, the catheter may also include a mechanical agitator for further disrupt clot in the presence of the thrombolytic agent. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.
Michael Evans - Palo Alto CA, US Denise Demarais - Los Gatos CA, US Dino De Cicco - San Jose CA, US Kelvin Ning - Palo Alto CA, US Alexander Khairkhahan - Palo Alto CA, US Tyler Strang - Palo Alto CA, US Jody Cimbalo - Mountain View CA, US Stephen Leeflang - Stanford CA, US
Assignee:
BACCHUS VASCULAR INC. - Santa Clara CA
International Classification:
A61B017/22
US Classification:
606/127000, 604/192000, 606/200000
Abstract:
Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, agitate the clot and agent, and aspirate broken-up clot from the blood vessel. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.
Magnetic Navigation Enabled Delivery Tools And Methods Of Making And Using Such Tools
Thao Ngo - Shakopee MN, US Tyler Strang - Valencia CA, US Vitaliy Epshteyn - Maple Grove CA, US Lior Sobe - Kadima, IL Ran Sela - Tel-Aviv, IL Guy Vanney - Blaine MN, US
Assignee:
PACESETTER, INC. - Sylmar CA
International Classification:
A61B 17/00 A61B 5/055 H01R 43/00
US Classification:
600424, 606129, 29825
Abstract:
Disclosed herein is a magnetic navigation enabled tool configured for the delivery of an implantable medical lead. The tool includes a tubular body, a sensor and a conductor. The tubular body includes a distal end, a proximal end, an inner layer including an outer circumferential surface, a lumen inward of the inner layer, and an outer layer over the outer circumferential surface of the inner layer. The sensor is on the tubular body near the distal end. The conductor extends from the sensor coil towards the proximal end imbedded in the inner layer.
Connector Sleeve For A Lead Of An Internal Pulse Generator
Li Jin - Cupertino CA, US Hanson Chang - Arcadia CA, US Keith Victorine - Santa Clarita CA, US Tyler Strang - Valencia CA, US Armando M. Cappa - Granada Hills CA, US
Assignee:
PACESETTER, INC. - Sylmar CA
International Classification:
G01R 31/04 H01R 11/22
US Classification:
324538, 439266
Abstract:
Implementations of the present disclosure involve an internal pulse generator for administering electrotherapy via an implantable medical lead having a lead connector end on a proximal end of the lead. In addition, implementations involve testing of the medical lead at the proximal lead connector end to ensure proper placement of the lead, and an interface device for facilitating the connection of the proximal lead connector end to a testing device. The interface device may provide for one or more electrical connection points disposed on a connector sleeve. The connection points provide electrical communication between the lead connector end of the lead and one or more leads of a testing device in such a manner as to minimize potential damage to the lead connector end.
Biostimulator Feedthrough Having Integrated Electrode Cup
- Sylmar CA, US Thomas B. Eby - Mountain View CA, US Matthew G. Fishler - Scotts Valley CA, US Carl Lance Boling - San Jose CA, US Thomas Robert Luhrs - Santa Rosa CA, US Russell Klehn - Valencia CA, US Tyler J. Strang - Valencia CA, US Arees Garabed - North Hills CA, US Kavous Sahabi - Winnetka CA, US Brett Villavicencio - Valencia CA, US Wes Alleman - Saugus CA, US Alex Soriano - Ventura CA, US Matthew R. Malone - Snohomish WA, US Conor P. Foley - Santa Clarita CA, US
Assignee:
Pacesetter, Inc. - Sylmar CA
International Classification:
A61N 1/362 A61N 1/375 A61N 1/05
Abstract:
A leadless biostimulator, and an electrical feedthrough assembly for use therewith, are described herein. The leadless biostimulator comprises an electrode body including a cup having an electrode wall extending distally from an electrode base around an electrode cavity, an electrode tip mounted on a distal end of the electrode body, and a filler in the electrode cavity between the electrode base and the electrode tip, wherein the filler includes a therapeutic agent. The electrode tip is configured to be placed in contact with target tissue to which a pacing impulse is to be transmitted by the leadless biostimulator. A pin extends proximally from the electrode base, wherein the pin is configured to be into contact with an electrical connector of an electronics assembly within a housing of the leadless biostimulator, and wherein the electrical feedthrough assembly is configured to be mounted on the housing of the leadless biostimulator.
- Sylmar CA, US Tyler J. Strang - Valencia CA, US Keith Victorine - Valencia CA, US Wesley Alleman - Santa Clarita CA, US
International Classification:
A61N 1/375
Abstract:
A biostimulator, such as a leadless cardiac pacemaker, including coaxial fixation elements to engage or electrically stimulate tissue, is described. The coaxial fixation elements include an outer fixation element extending along a longitudinal axis and an inner fixation element radially inward from the outer fixation element. One or more of the fixation elements are helical fixation elements that can be screwed into tissue. The outer fixation element has a distal tip that is distal to a distal tip of the inner fixation element, and an axial stiffness of the outer fixation element is lower than an axial stiffness of the inner fixation element. The relative stiffnesses are based on one or more of material or geometric characteristics of the respective fixation elements. Other embodiments are also described and claimed.