Tomy T Varghese

US Patent:

7166075, Jan 23, 2007

Filed:

Mar 8, 2002

Appl. No.:

10/094844

Inventors:

Tomy Varghese - Madison WI, US
James A. Zagzebski - Madison WI, US
Udomchai Techavipoo - Madison WI, US
Quan Chen - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61B 8/00

US Classification:

600439, 600407, 600437, 600442, 600446, 600462, 600463, 600466, 606 27, 606 28, 606 29, 606 30, 606 31, 606 41, 601 2, 601 3, 601 4

Abstract:

Elastographic images provide visualization in two or three dimensions of RF ablation lesions to guide in the ablation process. Compression may be applied using the RF probe. A similar technique may be applied to in vivo imaging of soft tissue without ablation.

US Patent:

7275439, Oct 2, 2007

Filed:

Feb 4, 2004

Appl. No.:

10/772663

Inventors:

James A. Zagzebski - Madison WI, US
Tomy Varghese - Madison WI, US
Anthony L. Gerig - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

G01N 29/036
A61B 1/00

US Classification:

73625, 73628, 73659, 600447

Abstract:

Parametric ultrasonic measurements which characterize the structure of tissue, using information from an ultrasonic signal beyond amplitude information, are obtained by combining multiple ultrasonic signals acquired at different angles, thereby reducing the variance of the calculations. Such angular compounding may be applied to detecting scatterer size, spacing, density, and attenuation.

US Patent:

7297116, Nov 20, 2007

Filed:

Apr 21, 2003

Appl. No.:

10/420125

Inventors:

Tomy Varghese - Madison WI, US
Mark Alan Kliewer - Madison WI, US
James A. Zagzebski - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61B 8/00

US Classification:

600438, 600443, 600588

Abstract:

Elastography is used to examine soft tissue of the uterus to detect tumors and to evaluate the strength of the cervix of the uterus based on its elastographic properties.

US Patent:

7331926, Feb 19, 2008

Filed:

Feb 23, 2004

Appl. No.:

10/784526

Inventors:

Tomy Varghese - Madison WI, US
Udomchai Techavipoo - Madison WI, US
Quan Chen - Madison WI, US
James A. Zagzebski - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61B 8/00

US Classification:

600443

Abstract:

Ultrasonic signals obtained at a range of angles are fit to a material independent model to derive both axial and lateral strain and thus parameters dependent on lateral strain including Poisson's ratio and shear strain.

US Patent:

7601122, Oct 13, 2009

Filed:

Jan 27, 2004

Appl. No.:

10/765293

Inventors:

James A. Zagzebski - Madison WI, US
Tomy Varghese - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61B 8/00

US Classification:

600449, 600443, 600561, 600587, 600438, 600459

Abstract:

Ultrasonic strain measurements, which characterize the structure of tissue, may be obtained by combining multiple echo signals acquired at different compressions and at different angles. Such angular compounding may improve the quality of the elastic signal and provide at one time both an axial and lateral strain measurement.

US Patent:

7632230, Dec 15, 2009

Filed:

Mar 20, 2006

Appl. No.:

11/384607

Inventors:

Tomy Varghese - Madison WI, US
Hairong Shi - Madison WI, US
Hao Chen - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61B 8/00

US Classification:

600437, 600444, 600443, 600439, 600438, 600446, 600407, 73597

Abstract:

High-resolution elastography employs a multiple-step process in which successively finer samplings of data and smaller areas of data are evaluated to provide increasingly accurate displacement measurements, wherein each displacement measurement guides the determination of corresponding regions of comparison used in the next displacement evaluation.

US Patent:

8328726, Dec 11, 2012

Filed:

Apr 1, 2009

Appl. No.:

12/416485

Inventors:

Tomy Varghese - Madison WI, US
Shyam Bharat - Madison WI, US

International Classification:

A61B 8/14
A61B 8/00
A61B 5/103
A61B 5/117
A61B 18/04

US Classification:

600471, 600438, 600587, 606 27

Abstract:

Real-time monitoring of tissue ablation is possible by using a vibrating ablation needle coupling lateral shear waves to the tissue. Ultrasonic imaging may characterize the velocity of these shear waves to reveal Young's modulus of the tissue and, at a discontinuity in Young's modulus, a boundary of the ablated lesion reflecting an underlying increase in stiffness of ablated tissue. This technique may be coupled with quasi-static elastography-based ablation monitoring techniques for improved measurement.

US Patent:

8403850, Mar 26, 2013

Filed:

Mar 25, 2008

Appl. No.:

12/054830

Inventors:

Tomy Varghese - Madison WI, US
Hao Chen - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61B 8/00

US Classification:

600438, 600449, 600443, 382128

Abstract:

An elastographic imaging system providing for axial, lateral and elevational strain measurements employs a series of one-dimensional axial measurements to deduce a coarse axial, lateral and/or elevational displacement that is used to guide one or more, two- or three-dimensional cross-correlations of smaller kernels providing improved image resolution.