A method for determining the quality of predicted nucleotide base identifications by receiving training data sets of predicted base identifications; defining subsets within the training data sets; comparing the predicted base identifications with actual base identifications within each subset; determining one or more sampling characteristics for each subset; and determining quality characterizations based on the comparison and the determined sampling characteristics.
Jerzy Kakol - San Diego CA, US Tobias Mann - Carlsbad CA, US Timothy K. McDaniel - San Diego CA, US
Assignee:
Illumina, Inc. - San Diego CA
International Classification:
C07H 21/02 C07H 21/04 C12Q 1/68
US Classification:
536 243, 435 911
Abstract:
DNA compositions having nucleotide sequences that do not occur in nature. Also provided are fluorescently labeled DNA molecules and complementary DNA on solid substrates, such as microspheres.
Variation Analysis For Multiple Templates On A Solid Support
Francisco Garcia - San Diego CA, US Klaus Maisinger - San Diego CA, US Stephen Tanner - San Diego CA, US John Moon - San Diego CA, US Tobias Mann - San Diego CA, US Michael Lawrence Parkinson - San Diego CA, US Anthony James Cox - San Diego CA, US Haifang H. Ge - San Diego CA, US
International Classification:
G06K 9/00
US Classification:
382129
Abstract:
Methods and systems for analysis of image data generated from various reference points. Particularly, the methods and systems provided are useful for real time analysis of image and sequence data generated during DNA sequencing methodologies.
Method And System For Determining The Accuracy Of Dna Base Identifications
Embodiments disclosed herein relate to a method and system for determining the accuracy of DNA base identifications, based at least partly on sampling characteristics of subsets within training data sets.
- San Diego CA, US Klaus Maisinger - Essex, GB Stephen Tanner - San Diego CA, US John Moon - San Diego CA, US Tobias Mann - San Diego CA, US Michael Lawrence Parkinson - Reyrieux, FR Anthony James Cox - Essex, GB Haifang H. Ge - Essex, GB
International Classification:
G06T 7/00 G06T 7/33 G06T 7/246 G06T 7/90
Abstract:
Methods and systems for analysis of image data generated from various reference points. Particularly, the methods and systems provided are useful for real time analysis of image and sequence data generated during DNA sequencing methodologies.
- San Diego CA, US Klaus Maisinger - Essex, GB Stephen Tanner - San Diego CA, US John Moon - San Diego CA, US Tobias Mann - San Diego CA, US Michael Lawrence Parkinson - Reyrieux, FR Anthony James Cox - Essex, GB Haifang H. Ge - Essex, GB
International Classification:
G06T 7/00 G06T 7/33 G06T 7/246 G06T 7/90
Abstract:
Methods and systems for analysis of image data generated from various reference points. Particularly, the methods and systems provided are useful for real time analysis of image and sequence data generated during DNA sequencing methodologies.
Adaptive Biotechnologies Corp.
Senior Director of Software Engineering
Progenity, Inc. Feb 2013 - Mar 2017
Senior Director of Bioinformatics
Illumina Jul 2007 - Jan 2013
Senior Manager, Bioinformatics
University of Washington 2001 - 2007
Graduate Student
Jet Lab 1997 - 2001
Research Programmer, Machine Learning Systems
Education:
University of Washington 2002 - 2007
Doctorates, Doctor of Philosophy
University of Washington 2001 - 2002
Master of Science, Masters, Electrical Engineering
University of Washington 1991 - 1997
Bachelors, Bachelor of Arts, Bachelor of Science, Mathematics, Computer Science, Philosophy
Skills:
Bioinformatics Genomics Dna Machine Learning Sequencing Pcr Molecular Biology Biotechnology Algorithms Science R&D Data Analysis Microarray Dna Sequencing Genetics Life Sciences Polymerase Chain Reaction Research and Development Pcr Primer Design Primer Design Lifesciences Probe Design Quality Management Process Qc Regulatory Compliance Laboratory Information Management System Data Science Ivd Biomarker Discovery Biomarker Development Computational Biology Ngs Genotyping Clia/Cap