Timothy Kevin Kelly

US Patent:

8007833, Aug 30, 2011

Filed:

Sep 10, 2009

Appl. No.:

12/557102

Inventors:

John Hen - Bradenton FL, US
Roger Thomas - Pinehurst NC, US
Griscom Bettle - Sarasota FL, US
Timothy J. Kelly - Sarasota FL, US

Assignee:

Biolife, L.L.C. - Sarasota FL

International Classification:

A01N 59/16
A61M 31/00
A61M 37/00
A61B 17/20

US Classification:

424646, 604506, 604 46

Abstract:

A method of reducing infections associated with vascular access procedures. A powder containment device (PCD) is preferably adhesively attached to a skin area, the PCD having a hole formed centrally therethrough adapted to completely surround the catheter wound site. The open cavity formed by the PCD being attached to the skin is filled with a hemostatic agent of a salt ferrate and an insoluble cation exchange material. The salt ferrate combines with blood to form a trivalent Fe ion promoting blood clotting and producing oxygen at the wound site for bacteria reduction. The cation exchange material also forms a protective cover over the wound site as the trivalent Fe ion is formed. Semi-occlusive pressure is applied against the hemostatic agent for a time sufficient to arrest blood flow from the wound site right after inserting or removing the catheter. The PCD and hemostatic agent are then covered with an adhesive dressing. The occurrence of air embolisms introduced around the catheter is also reduced after the hemostatic agent has interacted to arrest blood flow around the catheter.

US Patent:

20200063112, Feb 27, 2020

Filed:

Sep 4, 2019

Appl. No.:

16/560608

Inventors:

- Bunnik, NL
Stephen Edward CONNOR - Cambridge, GB
Erik Jan VAN-DEN BERG - Vught, NL
Andrea VAN ELSAS - Oss, NL
Abhinav Alok SHUKLA - Morrisville NC, US
Heather Bethea HORNE - Raleigh NC, US
Susan COOK - Flemington NJ, US
Timothy Martin KELLY - Raleigh NC, US
Victoria Anne DOWLING - Boulder CO, US
Mialy Fanjamalala RAMAROSON - Cary NC, US

Assignee:

AM-Pharma B.V. - Bunnik

International Classification:

C12N 9/16
A61K 38/46
A61K 47/10
A61K 47/12
A61K 47/22
A61K 47/26
C12N 9/96

Abstract:

The invention relates to the field of downstream processing (DSP) of an alkaline phosphatase (AP). More specifically, it relates to a method for reducing host cell protein content in a composition comprising AP. The invention further relates to a composition comprising an AP and a reduced content of a host cell protein.

US Patent:

20170009217, Jan 12, 2017

Filed:

Jan 26, 2015

Appl. No.:

15/113699

Inventors:

- Bunnik, NL
Stephen Edward CONNER - Cambridge, GB
Erik Jan VAN DEN BERG - Vught, NL
Andrea VAN ELSAS - Oss, NL
Abhinav Alok SHUKLA - Morrisville NC, US
Heather Bethea HORNE - Durham NC, US
Susan COOK - Flemington NJ, US
Timothy Martin KELLY - Raleigh NC, US
Victoria Anne DOWLING - Boulder CO, US
Mialy Fanjamalala RAMAROSON - Cary NC, US

Assignee:

AM-PHARMA B.V. - Bunnik

International Classification:

C12N 9/16
A61K 47/10
A61K 47/22
A61K 47/26
A61K 38/46
A61K 47/12

Abstract:

The invention relates to the field of downstream processing (DSP) of an alkaline phosphatase (AP). More specifically, it relates to a method for reducing host cell protein content in a composition comprising AP. The invention further relates to a composition comprising an AP and a reduced content of a host cell protein.

US Patent:

20160206298, Jul 21, 2016

Filed:

Jan 21, 2016

Appl. No.:

15/002549

Inventors:

- Sarasota FL, US
Timothy J. Kelly - Sarasota FL, US
John Tifton Fordham - Indialantic FL, US
Mark Travi - Venice FL, US

International Classification:

A61B 17/00
A61B 17/135
A61B 17/132

Abstract:

A combination radial arm band and hemostatic material preferably including potassium ferrate and a cation ion exchange resin in powder or granular form (WOUNDSEAL) or formed into a solid tablet (STATSEAL) and having improved topical effectiveness in the arresting of blood flow from a puncture wound into the radial artery made during transradial diagnostic or interventional catheterization procedures. The combination reduces time and pressure needed to achieve hemostasis and decreases arterial damage as compared to use of a radial arm band alone. In one aspect of this disclosure, careful limitation of applied force and time of applied force against the STATSEAL tablet reduces likelihood of harm to the radial artery while minimizing time to achieve hemostasis.

Author:

Timothy B. Kelly

ISBN #:

0789014726

Author:

Timothy B. Kelly

ISBN #:

0789014734

Author:

Timothy Kelly

ISBN #:

0521686784

Author:

Timothy Kelly

ISBN #:

0914766317

Author:

Timothy Kelly

ISBN #:

0887533132

Author:

Timothy Kelly

ISBN #:

0932440878

Author:

Timothy V. Kelly

ISBN #:

0471776246

Author:

Timothy V. Kelly

ISBN #:

0764588435