Edwin H. Beachey - Memphis TN Thomas P. Poirier - Memphis TN Michael A. Kehoe - Durham, GB2
Assignee:
University of Tennessee Research Corp. (U.T.R.C.) - Knoxville TN
International Classification:
C12N 121 C12N 1531 C12N 1509 A01N 6300
US Classification:
4352523
Abstract:
Non-virulent aro-Salmonella typhimurium bacterium is disclosed into which has been cloned a heterologous nucleotide sequence encoding for the expression of Streptococcal M protein antigen from S. pyogenes seratype 5, which is effective to elicit opsonic antibodies against Streptococcal infections. The bacterium is useful for vaccination against Streptococcus pyogenes bacteria.
Therapeutic Compositions Against Streptococcal Infections, Transformed Hosts, Methods Of Immunization And Genetically Engineered Products
Edwin H. Beachey - Memphis TN Thomas P. Poirier - Memphis TN Michael A. Kehoe - Durham, GB2
Assignee:
University of Tennessee Research Corp. - Knoxville TN
International Classification:
A61K 3909 A61K 39112
US Classification:
424 93P
Abstract:
Non-virulent bacteria are disclosed into which have been cloned heterologous nucleotide sequences encoded for the expression of Streptococcal M protein antigens, which are effective to elicit opsonic antibodies against Streptococcal infections. These bacteria are useful for vaccination against Streptococcus pyogenes bacteria.
Name / Title
Company / Classification
Phones & Addresses
Thomas P. Poirier Infectious Diseases
Department of Health Florida Admn Public Health Pgm Admn Social/Manpower Pgm · Administrative Public Health Programs · Healyth Department · State Health Dept
Linda Bicchieri, Rosemarie Christie, Bob Sueltenfuss, Mario Merluzzi, Charles Medeiros, Anne Flaherty, John Leahy, Nancy Gallagher, Jane Woodman, George Kelly