Larry Apfelbaum - West Newton MA, US Peter L. Savage - Mont Vernon NH, US Mark Trumpler - Lexington MA, US John D. Doyle - Hollis NH, US Thomas Lynch - Hollis NH, US Ramesh Vaswani - Nashua NH, US
Assignee:
Empirix Inc. - Waltham MA
International Classification:
G06F009/45
US Classification:
703 2, 703 22, 703 17, 717126
Abstract:
A method of using a computer to analyze an extended finite state machine model of a system includes providing a graphical user interface that presents a table of rows, receiving data in at least one table row, and determining at least one path through the states and transitions of the extended finite state machine model using at least one of the rows in the table.
Method To Determine Responsiveness Of Cancer To Epidermal Growth Factor Receptor Targeting Treatments
Daphne Winifred Bell - Arlington MA, US Daniel A. Haber - Chestnut Hill MA, US Pasi Antero Janne - Newton MA, US Bruce E. Johnson - Brookline MA, US Thomas J. Lynch - Newton MA, US Matthew Meyerson - Concord MA, US Juan Guillermo Paez - Boston MA, US William R. Sellers - Chestnut Hill MA, US Jeffrey E. Settleman - Newton MA, US Raffaella Sordella - Bedford MA, US
Assignee:
The General Hospital Corporation - Boston MA Dana-Farber Cancer Institute, Inc. - Boston MA
International Classification:
C12Q 1/68
US Classification:
435 6, 424 91, 435 912
Abstract:
The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
Laurence S. Gillick - Newton MA, US Thomas E. Lynch - Framingham MA, US Michael J. Newman - Somerville MA, US Daniel L. Roth - Boston MA, US Steven A. Wegmann - Cambridge MA, US Jonathan P. Yamron - Sudbury MA, US
Assignee:
Voice Signal Technologies, Inc. - Woburn MA
International Classification:
G10L 15/00
US Classification:
704254
Abstract:
A method for speech recognition. The method uses a single pronunciation estimator to train acoustic phoneme models and recognize utterances from multiple languages. The method includes accepting text spellings of training words in a plurality of sets of training words, each set corresponding to a different one of a plurality of languages. The method also includes, for each of the sets of training words in the plurality, receiving pronunciations for the training words in the set, the pronunciations being characteristic of native speakers of the language of the set, the pronunciations also being in terms of subword units at least some of which are common to two or more of the languages. The method also includes training a single pronunciation estimator using data comprising the text spellings and the pronunciations of the training words.
Method To Determine Responsiveness Of Cancer To Epidermal Growth Factor Receptor Targeting Treatments
Daphne Winifred Bell - Arlington MA, US Daniel A. Haber - Chestnut Hill MA, US Pasi Antero Janne - Newton MA, US Bruce E. Johnston - Brookline MA, US Thomas J. Lynch - Newton MA, US Matthew Meyerson - Concord MA, US Juan Guillermo Paez - Boston MA, US William R. Sellers - Chestnut Hill MA, US Jeffrey E. Settleman - Newton MA, US Raffaella Sordella - Bedford MA, US
Assignee:
The General Hospital Corporation - Boston MA Dana-Farber Cancer Institute, Inc. - Boston MA
International Classification:
C12Q 1/68
US Classification:
435 6
Abstract:
The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
Laurence S. Gillick - Newton MA, US Thomas E. Lynch - Framingham MA, US Michael J. Newman - Somerville MA, US Daniel L. Roth - Boston MA, US Steven A. Wegmann - Cambridge MA, US Jonathan P. Yamron - Sudbury MA, US
Assignee:
Voice Signal Technologies, Inc. - Woburn MA
International Classification:
G10L 15/06 G10L 15/28
US Classification:
704243, 704255
Abstract:
A method for speech recognition. The method uses a single pronunciation estimator to train acoustic phoneme models and recognize utterances from multiple languages. The method includes accepting text spellings of training words in a plurality of sets of training words, each set corresponding to a different one of a plurality of languages. The method also includes, for each of the sets of training words in the plurality, receiving pronunciations for the training words in the set, the pronunciations being characteristic of native speakers of the language of the set, the pronunciations also being in terms of subword units at least some of which are common to two or more of the languages. The method also includes training a single pronunciation estimator using data comprising the text spellings and the pronunciations of the training words.
Method To Determine Responsiveness Of Cancer To Epidermal Growth Factor Receptor Targeting Treatments
Daphne Winifred Bell - Arlington MA, US Daniel A. Haber - Chestnut Hill MA, US Pasi Antero Janne - Newton MA, US Bruce E. Johnston - Brookline MA, US Thomas J. Lynch - Newton MA, US Matthew Meyerson - Concord MA, US Juan Guillermo Paez - Boston MA, US William R. Sellers - Chestnut Hill MA, US Jeffrey E. Settleman - Newton MA, US Raffaella Sordella - Bedford MA, US
Assignee:
The General Hospital Corporation - Boston MA Dana-Farber Cancer Institute, Inc. - Boston MA
International Classification:
C12Q 1/68
US Classification:
435 6
Abstract:
The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
Method To Determine Responsiveness Of Cancer To Epidermal Growth Factor Receptor Targeting Treatments
Daphne Winifred Bell - Arlington MA, US Daniel A. Haber - Chestnut Hill MA, US Pasi Antero Janne - Newton MA, US Bruce E. Johnston - Brookline MA, US Thomas J. Lynch - Newton MA, US Matthew Meyerson - Concord MA, US Juan Guillermo Paez - Boston MA, US William R. Sellers - Chestnut Hill MA, US Jeffrey E. Settleman - Newton MA, US Raffaella Sordella - Bedford MA, US
Assignee:
The General Hospital Corporation - Boston MA Dana Farber Cancer Institute, Inc. - Boston MA
International Classification:
C12Q 1/68
US Classification:
435 61
Abstract:
The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
Method To Determine Responsiveness Of Cancer To Epidermal Growth Factor Receptor Targeting Treatments
The General Hospital Corporation - , US Dana Farber Cancer Institute, Inc. - , US Pasi Antero JANNE - Newton MA, US Bruce E. JOHNSTON - Brookline MA, US Thomas J. LYNCH - Newton MA, US Matthew MEYERSON - Concord MA, US Juan Guillermo PAEZ - Boston MA, US William R. SELLERS - Chesnut Hill MA, US Jeffrey E. SETTLEMAN - Newton MA, US Raffaella SORDELLA - Bedford MA, US
Assignee:
Dana Farber Cancer Institute, Inc. - Boston MA The General Hospital Corporation - Boston MA
International Classification:
C12Q 1/68
US Classification:
506 16, 435 611, 536 2431
Abstract:
Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
55 Fruit St Suite 7Th, Boston, MA 02114 617 724-1136 (Phone), 617 724-1137 (Fax)
Boston Office 55 Fruit St, Boston, MA 02114 617 726-2000 (Phone), 617 724-8500 (Fax)
Certifications:
Internal Medicine, 1989 Medical Oncology, 1991
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
55 Fruit St Suite 7Th, Boston, MA 02114
Boston Office 55 Fruit St, Boston, MA 02114
Dana - Farber Cancer Institute 450 Brookline Avenue, Boston, MA 02115
Massachusetts General Hospital 55 Fruit Street, Boston, MA 02114
Education:
Medical School Yale University Graduated: 1986 Medical School Massachusetts General Hospital Graduated: 1986 Medical School Dana-Farber Cancer Inst Graduated: 1986
Thomas J Lynch, Brockton MA - PA (Physician assistant; also Posterior–anterior)
Children's Community PediatricsChildrens Community Pediatrics 100 Medical Arts Bldg Ste 170, Kittanning, PA 16201 724 548-8591 (phone), 724 543-4380 (fax)
Children's Community PediatricsChildrens Community Pediatrics 619 S Pike Rd STE 100, Sarver, PA 16055 724 295-6555 (phone), 724 295-6550 (fax)
Leechburg Primary Care Center 116 Main St, Leechburg, PA 15656 724 845-1211 (phone), 724 845-5465 (fax)
Education:
Medical School SUNY Upstate Medical University Graduated: 1990
Dr. Lynch graduated from the SUNY Upstate Medical University in 1990. He works in Kittanning, PA and 2 other locations and specializes in Pediatrics and Adolescent Medicine. Dr. Lynch is affiliated with Armstrong Center For Medicine & Health, Childrens Home Of Pittsburgh, Childrens Hospital Of Pittsburgh Of UPMC and UPMC Presbyterian.
Richard L Roudebush VA Medical Center Primary Care 1481 W 10 St STE E3000, Indianapolis, IN 46202 317 988-4498 (phone), 317 988-5357 (fax)
Education:
Medical School University of Illinois, Chicago College of Medicine Graduated: 1987
Procedures:
Destruction of Benign/Premalignant Skin Lesions Electrocardiogram (EKG or ECG)
Conditions:
Atrial Fibrillation and Atrial Flutter Benign Prostatic Hypertrophy Chronic Renal Disease Diabetes Mellitus (DM) Disorders of Lipoid Metabolism
Languages:
English
Description:
Dr. Lynch graduated from the University of Illinois, Chicago College of Medicine in 1987. He works in Indianapolis, IN and specializes in Internal Medicine. Dr. Lynch is affiliated with Richard L Roudebush VA Medical Center.
Dr. Lynch graduated from the Loyola University Chicago Stritch School of Medicine in 1974. He works in Darien, IL and specializes in Pediatrics and Adolescent Medicine. Dr. Lynch is affiliated with Adventist Hinsdale Hospital.
Columbia Orthopedics 161 Ft Washington Ave FL 2, New York, NY 10032 212 305-4565 (phone), 212 305-6193 (fax)
Education:
Medical School Georgetown University School of Medicine Graduated: 2008
Languages:
English
Description:
Dr. Lynch graduated from the Georgetown University School of Medicine in 2008. He works in New York, NY and specializes in Orthopaedic Surgery and Orthopedic Sports Medicine. Dr. Lynch is affiliated with Morgan Stanley Childrens Hospital and New York Presbyterian Westchester Division.
Internal Medicine Hematology & Oncology Hematology Medical Oncology
Work:
Massachusetts General Hospital
55 Fruit St, Boston, MA 02114 Yale University
800 Howard Ave, New Haven, CT 06519 Yale University
1 Long Wharf Dr, New Haven, CT 06511
Multiple Locations Boston, MA Sep 1990 to Sep 2013 Drilling Manager
Education:
Bishop Fenwick High School Peabody, MA 1978 to 1981 High School Diploma in College PrepEssex Agricultural Middleton, MA 1982 AS in Applied Science
Skills:
Training OSHA 10 Hour OSHA 30 Hour HAZMAT 40 Hour Respirator Hoisting License First Aid CPR American Welding Society Member Concrete Field Test Tech. Certificate
MAERSK LINE LTD Norfolk, VA 2005 to 2014 CHIEF ENGINEERM.V. Green Cove New Orleans, LA 1996 to 2005 Chief engineerFIRST ASSISTANT ENGINEER HANSEATIC SHIPPING COMPANY, CYPRUS 1994 to 1995COASTAL BARGE CORPORATION
1993 to 1994 FIRST ASSISTANT ENGINEER
Education:
Massachusetts Maritime Academy Buzzards Bay, MA 1986 B.S. in EngineeringCalhoon M.E.B.A. Engineering School. Education
2011 to 2000 owner - online coffee cake businessNova Biomedical Corp Waltham, MA 2000 to 2011 BuyerMicrowave Medical Systems Acton, MA 1993 to 2000 Materials Coordinator / BuyerHoneywell Electro-Optics Division Wilmington, MA 1983 to 1993 Stockroom Clerk
Education:
Fisher College Malden, MA 1999 to 2000 AssociatesSomerville High School Somerville, MA 1983
Wikipedia References
Thomas Lynch
About:
Died:
1684
Work:
Position:
Governor • Chief Justice • President • Justice • Sheriff
General Liability Premises Liability No Fault Motor Vehicle Civil Rights Property Damage Claims Zoning Law Land Use
ISLN:
905298991
Admitted:
1973
University:
Canisius College, B.S., 1968
Law School:
State University of New York at Buffalo, J.D., 1972
Name / Title
Company / Classification
Phones & Addresses
Thomas D. Lynch President
INTERFACE SYSTEMS GROUP, INC
13 Commercial Way, Milford, MA 01757 33 Hickory Hl Ln, Framingham, MA 01702
Thomas F. Lynch President
Blue Northern Trading Company Inc Whol Nondurable Goods
96 Ann Lee Rd, Harvard, MA 01451
Thomas J. Lynch President
PROJECT CONTEMPORARY COMPETITIVENESS INCORPORATED
320 Washington St Alumni Hall ROOM 209, North Easton, MA 02357 12 Colby Dr, Middleboro, MA 02346
Thomas E. Lynch President
SIERRA FOOTHILLS INVESTMENT CORP Investor
957 Alyssum Rd, Carlsbad, CA 92011 3941 Park Dr, Folsom, CA 95762 200 Gamay Pl, Folsom, CA 95762
Thomas D Lynch Director
INTERNATIONAL ACADEMY FOR INTERFAITH STUDIES
3801 N Mccoll Rd APT 425, McAllen, TX 78501 900 E Vermont Ave, McAllen, TX 78503 111 Willard St, Quincy, MA 02169
Thomas J. Lynch Director
Thermo Electron North America LLC Electrical/Electronic Manufacturing · Sale And Service Of Analytical Instrumentation & Scientific Equipment · Business Purpose: Leading Provider Of Analytical Instruments, Equipment, Reagents And Consumables, Software And Services For Research, Analysis, Discovery And Diagnostics · 380 · Computer-General · Leading provider of analytical instruments, equipment, reagents and consumables, software and services for research, analysis, discovery and diagnostics. · Provider of Portable X-Ray Analyzers · Sale & Service Analytical Instrumentatio
1400 Northpoint Pkwy, West Palm Beach, FL 33407 81 Wyman St, Waltham, MA 02454 1400 Northpoint Pkwy Suite #10, West Palm Beach, FL 33407 800 Brazos SUITE 400, Austin, TX 78701 561 688-8700, 781 622-1000
Thomas Lynch Vice-President
Worcester Natural History Society Museum/Art Gallery
222 Harrington Way, Worcester, MA 01604 508 929-2700
Hickory Hills, ILLaw Offices Of Thomas W Lynch & Associates P C Attorney Thomas W. Lynch's background as an agent for the Internal Revenue Service and as an Assistant Illinois Attorney General, in the Civil Tax and... Attorney Thomas W. Lynch's background as an agent for the Internal Revenue Service and as an Assistant Illinois Attorney General, in the Civil Tax and Charitable Corporations Divisions, provides his clients with a wealth of experience for dealing with Financial, Tax, and Real Estate issues. Since...
El Dorado Hills, CACEO--Sierra Foothills Investment, Corp.
Real Estate Broker
Married to Dr. Nancy Lynch, Superintendent, Placerville Union School District
Daughter Alyssa... CEO--Sierra Foothills Investment, Corp.
Real Estate Broker
Married to Dr. Nancy Lynch, Superintendent, Placerville Union School District
Daughter Alyssa is in Law School at the University of South Dakota, Vermillion
Becerra wouldalsobe the first attorney general appointed by a governor since Thomas Lynch, who waschosen by former Gov. Pat Brown in 1964. Few political appointments are likely to be as personal to the current governoras this one, given his own four-year stint as attorney general starting in 200
Date: Dec 01, 2016
Category: U.S.
Source: Google
Obama unlikely to see assault on Islamic State's Syria stronghold
"Raqqa is every bit as infested as Mosul, perhaps even more so," said Thomas Lynch, a National Defense University fellow and retired Army officer. "But there is an enormous investment by this administration in terms of going after Raqqa before it leaves office."
Date: Nov 07, 2016
Source: Google
4 cops won't be charged for shooting to death man in wheelchair
McDole was shot in1800 block of Tulip Streetafter police responded to the 911 call. The caller told policethat a man had shot himself and still had a gun. Four responding officers, Senior Cpl. Thomas Silva, Cpl.Thomas Lynch, Cpl.James MacColl and Dellose,opened fire on McDole.
Date: May 12, 2016
Category: U.S.
Source: Google
The top 30 What If... comics available on Marvel Unlimited
oom captures the brain, which somehow can still communicate, and the two have the weirdest conversation imaginable. Doom fights the Fantastic Four and Reed Richards finds himself in control of Doctor Dooms body as the Watcher quotes poetry from Thomas Lynch. The comic ends bizarrely as Doctor Doom,
Sunni terrorists tend to operate in a continuous, mid-to-high-intensity manner, seeing war against infidels and apostates as a perennial condition, according to Thomas Lynch, of the Institute for National Strategic Studies and formerly of Brookings Institution.
Date: Jan 04, 2016
Category: World
Source: Google
Frederick's of Hollywood closes all of its stores to fully focuses on online retail
We look forward to entering this new phase of the companys history and having access to the capital resources needed to implement a turnaround strategy that can take full advantage of the Fredericks of Hollywood brand, then-Chairman and CEO Thomas Lynch said at the time.
Date: Apr 18, 2015
Category: Business
Source: Google
This having difficulties lingerie manufacturer closes up shop
"We glance forward to coming into this new phase of the firm's background and having entry to the cash means necessary to put into practice a turnaround technique that can choose whole advantage of the Frederick's of Hollywood brand name," then-Chairman and CEO Thomas Lynch claimed at the time.
Date: Apr 17, 2015
Category: Business
Source: Google
ISIS reportedly burn to death 45 people in western Iraqi town
But even if Islamic State militants close in on the base, taking it would require a massive force, that would present a target for airstrikes, retired Col. Thomas Lynch, a National Defense University fellow, told Fox News.
The Law Offices Of Thomas W. Lynch & Associates, P.C. - Partner (1992)
Education:
John Marshall Law School - Law, DePaul University - Acounting
About:
Attorney Thomas W. Lynch‘s background as an agent for the Internal Revenue Service (seven years) and as an Assistant Illinois Attorney General, in the Civil Tax and Charitable Corporations Divisions (...
Tagline:
Experienced Local Bankruptcy and Tax Attorney
Thomas Lynch
Work:
Tom Lynch Photography - Owner/Photographer
Education:
University of Iowa - Pharmacy, Iowa State University - Chemistry
Thomas Lynch
Work:
Mr. Searchwell - Bagger (2005)
Education:
School of Hard Knocks - Manliness
Tagline:
I am a super genius who due to government sanctions is forced to network socially to stop me from destroying the world.
Thomas Lynch
Education:
University of Phoenix - MBA, University of Phoenix - BS Business Management