Thomas Roger Gaborski

US Patent:

8119394, Feb 21, 2012

Filed:

Mar 14, 2007

Appl. No.:

11/686196

Inventors:

James L. McGrath - Fairport NY, US
Thomas R. Gaborski - Pittsford NY, US
Christopher C. Striemer - Rochester NY, US
Philippe M. Fauchet - Pittsford NY, US

Assignee:

University of Rochester - Rochester NY

International Classification:

C12M 3/06
C12M 1/34

US Classification:

4352971, 435 30, 435401, 4352885, 4352887, 4352975

Abstract:

Disclosed is a device for co-culturing two or more populations of cells using ultrathin, porous membranes positioned between cell culture chambers. Multiple chamber devices and uses thereof are described, including the formation of in vitro tissue models for studying drug delivery, cell-cell interactions, and the activity of low abundance molecular species.

US Patent:

8182590, May 22, 2012

Filed:

May 1, 2006

Appl. No.:

11/414991

Inventors:

Christopher C. Striemer - Rochester NY, US
Philippe M. Fauchet - Pittsford NY, US
Thomas R. Gaborski - Pittsford NY, US
James L. McGrath - Fairport NY, US

Assignee:

University of Rochester - Rochester NY

International Classification:

B01D 53/22
B01D 39/00
B01D 39/14
B01D 71/04

US Classification:

96 4, 96 5, 96 6, 96 7, 96 8, 96 9, 96 10, 96 11, 96 12, 96 13, 96 14, 96 54, 96 55, 96 56, 21050021, 21050025, 21050027, 210640

Abstract:

A process for forming a porous nanoscale membrane is described. The process involves applying a nanoscale film to one side of a substrate, where the nanoscale film includes a semiconductor material; masking an opposite side of the substrate; etching the substrate, beginning from the masked opposite side of the substrate and continuing until a passage is formed through the substrate, thereby exposing the film on both sides thereof to form a membrane; and then simultaneously forming a plurality of randomly spaced pores in the membrane. The resulting porous nanoscale membranes, characterized by substantially smooth surfaces, high pore densities, and high aspect ratio dimensions, can be used in filtration devices, microfluidic devices, fuel cell membranes, and as electron microscopy substrates.

US Patent:

8518276, Aug 27, 2013

Filed:

Apr 20, 2012

Appl. No.:

13/452453

Inventors:

Christopher C. Striemer - Rochester NY, US
Philippe M. Fauchet - Pittsford NY, US
Thomas R. Gaborski - Pittsford NY, US
James L. McGrath - Fairport NY, US

Assignee:

University of Rochester - Rochester NY

International Classification:

C23F 1/00
C03C 15/00

US Classification:

216 2, 216 41, 977778, 977781, 977890

Abstract:

A process for forming a porous nanoscale membrane is described. The process involves applying a nanoscale film to one side of a substrate, where the nanoscale film includes a semiconductor material; masking an opposite side of the substrate; etching the substrate, beginning from the masked opposite side of the substrate and continuing until a passage is formed through the substrate, thereby exposing the film on both sides thereof to form a membrane; and then simultaneously forming a plurality of randomly spaced pores in the membrane. The resulting porous nanoscale membranes, characterized by substantially smooth surfaces, high pore densities, and high aspect ratio dimensions, can be used in filtration devices, microfluidic devices, fuel cell membranes, and as electron microscopy substrates.

US Patent:

20050106629, May 19, 2005

Filed:

Aug 26, 2004

Appl. No.:

10/928478

Inventors:

James McGrath - Fairport NY, US
Ian Schwartz - Deansboro NY, US
Michael Bindschadler - Rochester NY, US
Morton Ehrenberg - Rochester NY, US
Thomas Gaborski - Rochester NY, US

Assignee:

University of Rochester - Rochester NY

International Classification:

G01N033/53
C12Q001/42
C12N009/00

US Classification:

435007100, 435183000

Abstract:

The invention provides methods and compositions for using actin for making micro- and nano-scale structures, including-masking of two-dimentsional surfaces and non-conductive three dimensional spacers.

US Patent:

20120171087, Jul 5, 2012

Filed:

Oct 1, 2010

Appl. No.:

13/496012

Inventors:

Thomas R. Gaborski - Rochester NY, US
James L. McGrath - Fairport NY, US
Richard D. Richmond - Canandaigua NY, US
Christopher C. Striemer - Rochester NY, US

Assignee:

SIMPORE, INC. - West Henrietta NY

International Classification:

B01L 3/00
B01D 69/02
F15D 1/00
B82Y 40/00
B82Y 30/00
B82Y 99/00

US Classification:

422533, 21050021, 137 1, 977780, 977902, 977840

Abstract:

The present invention is drawn to methods for facilitating fluid flow through the nanopores of membranes, i.e., through sub-micron pores. The present invention is also directed to one or more apparatus for such fluid flow, and for nanoporous membranes modified to facilitate such fluid flow.

US Patent:

20160115951, Apr 28, 2016

Filed:

Oct 27, 2014

Appl. No.:

14/524024

Inventors:

- Rochester NY, US
- West Henrietta NY, US
Philippe Fauchet - Brentwood TN, US
Thomas Gaborski - Rochester NY, US
Christopher C. Striemer - Rochester NY, US

International Classification:

F04B 43/04

Abstract:

Thin pnc-Si membranes operate as high-flow-rate EOPs at low applied voltages. In at least some instances, this may be due to the small electrical resistance presented by the membrane and high electric fields across the molecularly thin membrane. The normalized flow rates of some pnc-Si EOPs may be 20 times to several orders of magnitude higher than other low-voltage EOPs.