Thomas H Faitg

US Patent:

7354933, Apr 8, 2008

Filed:

Feb 2, 2004

Appl. No.:

10/770382

Inventors:

Marcel Patek - Tucson AZ, US
Anil Nair - Tucson AZ, US
Augustin Hittinger - Igny, FR
Conception Nemecek - Thiais, FR
Daniel Bond - Tucson AZ, US
Greg Harlow - Boulder CO, US
Herve Bouchard - Thiais, FR
Jacques Mauger - Tucson AZ, US
Jean-Luc Malleron - Marcoussis, FR
Mark Palermo - Rindge NH, US
Fahad Al-Obeidi - Tucson AZ, US
Thomas Faitg - Exton PA, US
Hartmut Strobel - Liederbach, DE
Sven Ruf - Floersheim, DE
Kurt Ritter - Frankfurt Am Main, DE
Youssef El-Ahmad - Creteil, FR
Dominique Lesuisse - Montreuil, FR
Didier Bénard - Attainville, FR

Assignee:

Aventis Pharma SA - Antony

International Classification:

C07D 401/06
C07D 403/06
A61K 31/41

US Classification:

514314, 514341, 514389, 514391, 546172, 5462744, 5483191

Abstract:

The present invention relates to a cyclic urea compound of formula I:.

US Patent:

7666863, Feb 23, 2010

Filed:

May 24, 2007

Appl. No.:

11/753145

Inventors:

Ashis K. Saha - Harleysville PA, US
Christopher J Burns - Malvern PA, US
Alfred M. Del Vecchio - West Chester PA, US
Thomas R. Bailey - Phoenixville PA, US
Jason A. Reinhardt - Audubon PA, US
Bheemashankar A. Kulkarni - Exton PA, US
Thomas H. Faitg - Exton PA, US
Hao Feng - Aston PA, US
Susan R. Rippin - Wilmington DE, US
Charles W. Blackledge - Spring City PA, US
David J. Rys - Philadelphia PA, US
Thomas A. Lessen - Langhorne PA, US
John Swestock - Reading PA, US
Yijun Deng - Dresher PA, US
Theodore J. Nitz - Pottstown PA, US

Assignee:

ViroPharma Incorporated - Exton PA
WYETH - Madison NJ

International Classification:

A61K 31/54
A61K 31/53
C07D 307/00
C07D 401/00
C07D 417/00

US Classification:

5142222, 5142265, 5142288, 514241, 51425201, 514279, 514337, 514359, 514365, 514383, 514408, 514444, 514468, 514469, 549469, 548146, 548215, 548256, 5483111, 544 60, 544 66, 544111, 544152, 544153, 544179

Abstract:

The present invention relates to benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.

US Patent:

7825115, Nov 2, 2010

Filed:

Jan 10, 2008

Appl. No.:

11/972314

Inventors:

Marcel Patek - Tucson AZ, US
Anil Nair - Tucson AZ, US
Augustin Hittinger - Igny, FR
Conception Nemecek - Thiais, FR
Daniel Bond - Tucson AZ, US
Greg Harlow - Boulder CO, US
Herve Bouchard - Thiais, FR
Jacques Mauger - Tucson AZ, US
Jean-Luc Malleron - Marcoussis, FR
Mark Palermo - Rindge NH, US
Fahad Al-Obeidi - Tucson AZ, US
Thomas Faitg - Exton PA, US
Hartmut Strobel - Liederbach, DE
Sven Ruf - Floersheim, DE
Kurt Ritter - Frankfurt Am Main, DE
Youssef El-Ahmad - Creteil, FR
Dominique Lesuisse - Montreuil, FR
Didier Bénard - Attainville, FR

Assignee:

Aventis Pharma S.A. - Antony

International Classification:

C07D 401/06
C07D 403/06
A61K 31/41

US Classification:

5142355, 5142372, 51425218, 514278, 514312, 514314, 514318, 514333, 514338, 544124, 544364, 546 15, 546152, 546153, 546187, 546256, 5462731

Abstract:

The disclosure relates to a cyclic urea compound of formula I:.

US Patent:

7884098, Feb 8, 2011

Filed:

Jan 25, 2008

Appl. No.:

12/524009

Inventors:

Jeffrey Michael Axten - Collegeville PA, US
Deborah L. Bryan - Collegeville PA, US
David Harold Drewry - Durham NC, US
Thomas H Faitg - Collegeville PA, US
Timothy Francis Gallagher - Collegeville PA, US
Neil W Johnson - Collegeville PA, US
Jiri Kasparec - Collegeville PA, US
Jeffrey M Ralph - Collegeville PA, US
Domingos J. Silva - Collegeville PA, US

Assignee:

GlaxoSmithKline LLC - Philadelphia PA

International Classification:

A61K 31/5355
A61K 31/541
A61K 31/505
A61K 31/506
C07D 279/12
C07D 403/02
C07D 239/24
C07D 413/02

US Classification:

5142278, 5142358, 51425214, 514275, 544 582, 544 584, 544122, 544295, 544323

Abstract:

The present invention relates to a compound represented by the following formula:.

US Patent:

20040162318, Aug 19, 2004

Filed:

Oct 31, 2003

Appl. No.:

10/699336

Inventors:

Ashis Saha - Harleysville PA, US
Christopher Burns - Malvern PA, US
Alfred Del Vecchio - West Chester PA, US
Thomas Bailey - Phoenixville PA, US
Jason Reinhardt - Audubon PA, US
Bheemashankar Kulkarni - Exton PA, US
Thomas Faitg - Exton PA, US
Hao Feng - Aston PA, US
Susan Rippin - Wilmington DE, US
Charles Blackledge - Spring City PA, US
David Rys - , US
Thomas Lessen - Langhorne PA, US
John Swestock - Reading PA, US
Yijun Deng - Dresher PA, US
Theodore Nitz - Pottstown PA, US

International Classification:

C 07D 4 5/02
A61K031/4433
A61K031/4025

US Classification:

514/337000, 514/422000, 514/469000, 546/284100, 548/525000, 549/443000

Abstract:

The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.

US Patent:

20080242667, Oct 2, 2008

Filed:

Aug 23, 2006

Appl. No.:

12/064820

Inventors:

Jerry Leroy Adams - Collegeville PA, US
Thomas H. Faitg - Collegeville PA, US
Jeffrey M. Ralph - Collegeville PA, US
Domingos J. Silva - Collegeville PA, US

International Classification:

A61K 31/5377
C07D 413/02
A61K 31/496
A61P 35/00
C07D 403/02

US Classification:

5142358, 544122, 544295, 51425214

Abstract:

The present invention provides a compound represented by Formula (I):or a salt thereof, or a solvate thereof, or a combination thereof, wherein the substituents are as defined herein.The present invention also relates to a composition comprising the compound of formula (I) and diluents, carriers, or excipients. Furthermore, the present invention relates to a method of treating a disease of cell proliferation comprising administering to a patient in need thereof a pharmaceutically effective amount of the compound of formula (I) or a salt thereof, or a solvate thereof, or a combination thereof.

US Patent:

20080293706, Nov 27, 2008

Filed:

May 8, 2008

Appl. No.:

12/117127

Inventors:

Amita CHAUDHARI - Collegeville PA, US
Dashyant DHANAK - Collegeville PA, US
Carla Ann DONATELLI - Collegeville PA, US
Thomas H. FAITG - Collegeville PA, US
Yanhong FENG - Collegeville PA, US
Steven David KNIGHT - Collegeville PA, US
Cynthia A. PARRISH - Collegeville PA, US
Jeffrey M. RALPH - Collegeville PA, US

International Classification:

A61K 31/498
C07D 413/14
C07D 241/36
A61K 31/541
A61P 35/02
A61P 35/00
C07D 279/12
A61K 31/5377

US Classification:

5142282, 544116, 544356, 544 582, 5142348, 514249

Abstract:

Invented is a method of inhibiting the activity/function of PI3 kinases using quinoxaline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoxaline derivatives.

US Patent:

20090281336, Nov 12, 2009

Filed:

Jul 9, 2009

Appl. No.:

12/499876

Inventors:

Ashis K. Saha - Harleysville PA, US
Christopher J. Burns - Malvern PA, US
Alfred M. Del Vecchio - West Chester PA, US
Thomas R. Bailey - Phoenixville PA, US
Jason A. Reinhardt - Audubon PA, US
Bheemashankar A. Kulkarni - Exton PA, US
Thomas H. Faitg - Exton PA, US
Hao Feng - Aston PA, US
Susan R. Rippin - Wilmington DE, US
Charles W. Blackledge - Spring City PA, US
David J. Rys - Philadelphia PA, US
Thomas A. Lessen - Langhorne PA, US
John Swestock - Reading PA, US
Yijun Deng - Dresher PA, US
Theodore J. Nitz - Pottstown PA, US

International Classification:

C07D 307/82

US Classification:

549467

Abstract:

The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.