Jose Reyes-Taboada - Mexico City, MX Xiuren Zhang - New York NY, US Takashi Soyano - New York NY, US Nam-Hai Chua - New York NY, US Qi-Wen Niu - Staten Island NY, US Shih-Shun Lin - New York NY, US
The invention provides methods and compositions useful in target sequence suppression, target sequence validation and target sequence down regulation. The invention provides polynucleotide constructs useful for gene silencing or RNA down regulation, as well as cells, plants and seeds comprising the polynucleotides. The invention also provides a method for using microRNA to silence a target sequence or to down regulate RNA.
- New York NY, US Xiuren ZHANG - New York NY, US Takashi SOYANO - New York NY, US Nam-Hai CHUA - New York NY, US Qi-Wen NIU - New York NY, US Shih-Shun LIN - New York NY, US
Assignee:
THE ROCKEFELLER UNIVERSITY - New York NY
International Classification:
C12N 15/113
Abstract:
The invention provides methods and compositions useful in target sequence suppression, target sequence validation and target sequence down regulation. The invention provides polynucleotide constructs useful for gene silencing or RNA down regulation, as well as cells, plants and seeds comprising the polynucleotides. The invention also provides a method for using microRNA to silence a target sequence or to down regulate RNA.