Suresh Babu Guruswamy

US Patent:

20060252817, Nov 9, 2006

Filed:

Apr 14, 2006

Appl. No.:

11/404701

Inventors:

Doris Benbrook - Oklahoma City OK, US
Martin Turman - Edmond OK, US
Suresh Guruswamy - Edmond OK, US

International Classification:

A61K 31/382

US Classification:

514432000

Abstract:

The present invention contemplates methods of treating, reducing, inhibiting or preventing several diseases by the administration of flexible heteroarotinoids. Among the diseases or conditions which can benefit from treatment with flexible heteroarotinoids as described herein are, (1) cancers and other diseases that involve abnormal differentiation, (2) diabetes, (3) hemophilia, (4) liver disease, (5) diseases involving human aldehyde dehydrogenase 2, (6) polycystic kidney disease, (7) lysosomal storage diseases, (8) high cholesterol, (9) obesity, (10) high triglycerides, (11) glycoprotein metabolism diseases, and (12) diseases involving abnormal angiogenesis.

US Patent:

20100105757, Apr 29, 2010

Filed:

Oct 29, 2009

Appl. No.:

12/608468

Inventors:

Doris M. Benbrook - Oklahoma City OK, US
Martin Turman - Edmond OK, US
Suresh Guruswamy - Edmond OK, US

International Classification:

A61K 31/382
A61P 7/12
A61P 1/16
A61P 13/12
A61P 3/04
A61P 3/00

US Classification:

514432

Abstract:

The present invention contemplates methods of treating, reducing, inhibiting or preventing several diseases by the administration of flexible heteroarotinoids. Among the diseases or conditions which can benefit from treatment with flexible heteroarotinoids as described herein are, (1) cancers and other diseases that involve abnormal differentiation, (2) diabetes, (3) hemophelia, (4) liver disease, (5) diseases involving human aldehyde dehydrogenase 2, (6) polycystic kidney disease, (7) lysosomal storage diseases, (8) high cholesterol, (9) obesity, (10) high triglycerides, (11) glycoprotein metabolism diseases, and (12) diseases involving abnormal angiogenesis.