Steven M Zeitels

US Patent:

6955645, Oct 18, 2005

Filed:

Feb 4, 2002

Appl. No.:

10/061256

Inventors:

Steven M. Zeitels - Boston MA, US

International Classification:

A61B001/267

US Classification:

600187, 600190, 600194, 600199

Abstract:

An element for a phonomicrosurgical modular glottiscope system comprises a proximal end; a distal end; a pair of opposing curved sides intersecting at an apex line; a substantially planar base, and internal channels disposed within the base. The base plate is removably attached to the pair of curved sides, and the base and curved sides define a lumen extending from the proximal end to the distal end. The internal channels include a first internal channel that provides illumination to the distal end and a second internal channel that provides aspiration to the distal end. In operation, the distal end of the element is inserted into a body cavity and the lumen provides visualization of the distal end and access to the distal end for tools inserted into the lumen from the proximal end. A method of manufacturing the element is also disclosed.

US Patent:

20050281412, Dec 22, 2005

Filed:

Jun 16, 2004

Appl. No.:

10/869666

Inventors:

Robert Hillman - Weston MA, US
Steven Zeitels - Boston MA, US
James Kobler - Andover MA, US
James Heaton - Mansfield MA, US
Ehab Goldstein - Somerville MA, US

International Classification:

A61F002/20

US Classification:

381070000, 623009000

Abstract:

A voice prosthesis includes a voice actuator for generating a signal to be modulated into speech and a neural interface for receiving a signal indicative of neural activity. A signal processing system in communication with both the neural interface and the voice actuator is configured to provide the voice actuator with a control signal representative of the neural activity.

US Patent:

20100055184, Mar 4, 2010

Filed:

Sep 3, 2009

Appl. No.:

12/553800

Inventors:

Steven M. Zeitels - Newton MA, US
Robert Edward Hillman - Weston MA, US
Sandeep Sidram Karajanagi - Malden MA, US
Robert S. Langer - Newton MA, US

International Classification:

A61K 9/00
C07C 43/11
C07C 31/18
C07K 14/00
C08B 37/00
C08B 37/02
C08B 37/04
C07K 14/78
A61P 19/04
C08B 15/06
A61K 35/00
A61K 35/12
A61K 38/02
A61K 38/16
A61K 31/7052

US Classification:

424484, 568679, 568852, 530402, 5361231, 536 551, 536 51, 530354, 530353, 530356, 536 30, 424 931, 424 937, 514 2, 514 12, 514 44 R

Abstract:

The present invention provides hydrogels and compositions thereof for vocal cord repair or augmentation, as well as other soft tissue repair or augmentation (e.g., bladder neck augmentation, dermal fillers, breast implants, intervertebral disks, muscle-mass). The hydrogels or compositions thereof are injected into the superficial lamina propria or phonatory epithelium to restore the phonatory mucosa of the vocal cords, thereby restoring a patient's voice. In particular, it has been discovered that hydrogels with an elastic shear modulus of approximately 25 Pa are useful in restoring the pliability of the phonatory mucosa. The invention also provides methods of preparing and using the inventive hydrogels.

US Patent:

20120065573, Mar 15, 2012

Filed:

Feb 5, 2010

Appl. No.:

13/147844

Inventors:

Steven M. Zeitels - Newton MA, US

Assignee:

THE GENERAL HOSPITAL CORPORATION - Boston MA

International Classification:

A61M 37/00
A61P 1/00
A61P 17/02
A61P 11/00
A61K 39/395
A61P 9/00

US Classification:

604 20, 4241581, 4241331

Abstract:

Described are methods of treating virus-associated lesions using administration of an anti-angiogenic compound, or a combination of angiolytic or ablative therapy and administration of an anti-angiogenic compound.

US Patent:

20130041467, Feb 14, 2013

Filed:

Mar 4, 2011

Appl. No.:

13/579347

Inventors:

Steven M. Zeitels - Newton MA, US
Robert E. Hillman - Weston MA, US
Sandeep Sidram Karajanagi - Malden MA, US
Robert S. Langer - Newton MA, US

Assignee:

MASSACHUSETTS INSTITUTE OF TECHNOLOGY - Cambridge MA
THE GENERAL HOSPITAL CORPORATION - Boston MA

International Classification:

A61F 2/00

US Classification:

623 1411

Abstract:

The disclosure relates to methods and systems for making customized treatments to a subject's vocal tissues to provide a desired level of vocal function.

US Patent:

20130211391, Aug 15, 2013

Filed:

Jan 21, 2011

Appl. No.:

13/574472

Inventors:

Adela BenYakar - Austin TX, US
Christopher L. Hoy - Leiden, NL
William Neil Everett - Cedar Park TX, US
James B. Kobler - West Roxburg MA, US
Richard Rox Anderson - Boston MA, US
William A. Farinelli - Danvers MA, US
Steven M. Zeitels - Newton MA, US

Assignee:

THE GENERAL HOSPITAL CORPORATION - Boston MA
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM - Austin TX

International Classification:

A61B 18/20

US Classification:

606 10

Abstract:

Provided herein are devices, systems and methods for treating a vocal fold pathology by forming a substantially planar void below the epithelium of the vocal fold using optical energy. Also provided are devices, systems, and methods for combined imaging and treating of a vocal fold pathology.

US Patent:

20130303842, Nov 14, 2013

Filed:

Sep 2, 2011

Appl. No.:

13/817275

Inventors:

Steven M. Zeitels - Newton MA, US
John C. Wain - Milton MA, US

Assignee:

THE GENERAL HOSPITAL CORPORATION - Boston MA

International Classification:

A61F 2/06

US Classification:

600 36

Abstract:

Compositions comprising aortic material and methods for using harvested blood vessels (e.g., arteries or veins e.g., aortae) graft procedures, e.g., for restoring and repairing luminal structures (e.g., in the aerodigestive tract, such as the larynx, pharynx, and esophagus); as tissue fillers (e.g., injectable morselized blood vessel tissues, for use in cosmetic applications and functional sphincter enhancement); and as biological structural supports (e.g., intact portions of aortae, for use in repairing abdominal wounds, anastomoses, bony repairs, and the heart).

US Patent:

50923145, Mar 3, 1992

Filed:

May 8, 1990

Appl. No.:

7/520647

Inventors:

Steven M. Zeitels - Jamaica Plain MA

International Classification:

A61B 126

US Classification:

128 10

Abstract:

An adjustable supraglottiscope designed to be used in the supraglottic larynx is disclosed, in particular, an improved apparatus for endoscopic surgery in the supraglottis and the lower pharynx is disclosed by having at least one blade that is at least as wide as the normal, human epiglottis in its natural position within the body. The blades of the supraglottiscope have a length to width ratio that is about one-half of that found in conventional instruments. This unique ratio enables a wider exposure of the supraglottic larynx and lower pharynx. Methods of performing surgery on the supraglottic larynx of a patient are also described.

Author:

Steven M. Zeitels

ISBN #:

0769301312