Silvia T Gonzales

US Patent:

20200282110, Sep 10, 2020

Filed:

May 20, 2020

Appl. No.:

16/878876

Inventors:

- Atlanta GA, US
Silvia Daniela Gonzales - Miami FL, US
Edgar S. Maldonado - Miami FL, US

International Classification:

A61L 27/36
A61L 27/22

Abstract:

A bone gel composition consists of cortical bone. The cortical bone is made from cut pieces freeze-dried then ground into particles and demineralized then freeze-dried. A volume of the particles is placed in a solution of sterile water to create a mixture, the water volume being at least twice the particle volume, the mixture is autoclaved under heat and pressure to form a gelatin, the resulting bone gel is formed into sheets having a thickness (t).

US Patent:

20180193526, Jul 12, 2018

Filed:

Mar 7, 2018

Appl. No.:

15/914529

Inventors:

- Atlanta GA, US
Silvia Daniela Gonzales - Miami FL, US

Assignee:

Vivex Biomedical, Inc. - Atlanta GA

International Classification:

A61L 27/36
A61L 27/22
A61F 2/46
A61F 2/28

Abstract:

A malleable demineralized bone composition consists of cortical bone made from a first portion and a second portion. The first portion of cortical bone is made from cut pieces freeze dried then ground into particles and demineralized then freeze-dried. The second portion of cortical bone is shaved into shavings. The shavings are long thin strips subjected to freeze-drying. The freeze-dried shavings are ground and demineralized and then freeze-dried. A volume of the second portion is placed in a solution of sterile water to create a mixture, the water volume being twice the second portion, the mixture is autoclaved under heat and pressure to form a gelatin, and the first portion is mixed with the gelatin to form a malleable putty or paste.

US Patent:

20170304053, Oct 26, 2017

Filed:

Apr 22, 2016

Appl. No.:

15/136339

Inventors:

- Marietta GA, US
Silvia Daniela Gonzales - Miami FL, US
Wendy W. Weston - Miami FL, US
Shabnam Namin - Miami FL, US

Assignee:

Vivex Biomedical, Inc. - Marietta GA

International Classification:

A61F 2/28
A61L 27/50
A61L 27/36
A61L 27/36
A61F 2/28
A61F 2/28

Abstract:

A moldable bone composition consists of a mixture of: cortical bone and cancellous bone. The cortical bone is formed in three portions, a mineralized shaving portion and a demineralized shaving portion and a mineralized powder portion. The cancellous bone is formed in a mineralized crushed cancellous portion. The portions are free-dried and mixed together to form a freeze-dried moldable bone composition.

US Patent:

20170304054, Oct 26, 2017

Filed:

Apr 22, 2016

Appl. No.:

15/136383

Inventors:

- Marietta GA, US
Silvia Daniela Gonzales - Miami FL, US
Wendy W. Weston - Miami FL, US

Assignee:

Vivex Biomedical, Inc. - Marietta GA

International Classification:

A61F 2/28
A61L 27/36
A61F 2/28

Abstract:

A bone gel composition consists of cortical bone. The cortical bone is made from cut pieces freeze-dried then ground into particles and demineralized then freeze-dried. A volume of the particles is placed in a solution of sterile water to create a mixture, the water volume being twice the second portion, the mixture is autoclaved under heat and pressure to form a gelatin, the resulting bone gel is placed in jars and kept at room temperature or frozen for later use. The cortical bone has the cut pieces having a width, a length and a thickness in the range of 1 to 4 mm The cortical bone pieces are ground to a particle size up to 125 microns.

US Patent:

20170304055, Oct 26, 2017

Filed:

Apr 22, 2016

Appl. No.:

15/136534

Inventors:

- Marietta GA, US
Edgar S. Maldonado - Miami FL, US
Silvia Daniela Gonzales - Miami FL, US
Shabnam Namin - Miami FL, US

Assignee:

Vivex Biomedical, Inc. - Marietta GA

International Classification:

A61F 2/28
A61L 27/50
A61L 27/36
A61L 27/36
A61F 2/28

Abstract:

A cohesive bone composition is made from a moldable bone composition intermixed with a bone gel composition. The cohesive bone composition is made from human cadaver bone. A fluid can be added, the fluid may also be laden with cells.

US Patent:

20170304494, Oct 26, 2017

Filed:

Apr 22, 2016

Appl. No.:

15/136301

Inventors:

- Marietta GA, US
Silvia Daniela Gonzales - Miami FL, US

Assignee:

Vivex Biomedical, Inc. - Marietta GA

International Classification:

A61L 27/36
A61F 2/28
A61L 27/36
A61L 27/22
A61F 2/46

Abstract:

A malleable demineralized bone composition consists of cortical bone made from a first portion and a second portion. The first portion of cortical bone is made from cut pieces freeze dried then ground into particles and demineralized then freeze-dried. The second portion of cortical bone is shaved into shavings. The shavings are long thin strips subjected to freeze-drying. The freeze-dried shavings are ground and demineralized and then freeze-dried. A volume of the second portion is placed in a solution of sterile water to create a mixture, the water volume being twice the second portion, the mixture is autoclaved under heat and pressure to form a gelatin, and the first portion is mixed with the gelatin to form a malleable putty or paste.

US Patent:

20170304495, Oct 26, 2017

Filed:

Aug 15, 2016

Appl. No.:

15/236807

Inventors:

- Marietta GA, US
Silvia Daniela Gonzales - Miami FL, US
Edgar S. Maldonado - Miami FL, US

Assignee:

Vivex Biomedical, Inc. - Marietta GA

International Classification:

A61L 27/36
A61L 27/36
A61L 27/36
A61L 27/36

Abstract:

A bone gel composition consists of cortical bone. The cortical bone is made from cut pieces freeze-dried then ground into particles and demineralized then freeze-dried. A volume of the particles is placed in a solution of sterile water to create a mixture, the water volume being at least twice the particle volume, the mixture is autoclaved under heat and pressure to form a gelatin, the resulting bone gel is formed into sheets having a thickness (t).