Shaofeng Xie

US Patent:

7074331, Jul 11, 2006

Filed:

Jun 25, 2003

Appl. No.:

10/607080

Inventors:

Robert W. Allington - Lincoln NE, US
Shaofeng Xie - Lincoln NE, US
Tao Jiang - Lincoln NE, US
Mingcheng Xu - Lincoln NE, US

Assignee:

Dionex Corporation - Sunnyvale CA

International Classification:

B01D 15/08

US Classification:

210635, 210656, 210748, 2101982, 2105021

Abstract:

Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixture. The pressure eliminates wall effect and changes the structure in the column. Similarly, some columns that have a tendency to swell in the presence of aqueous solutions and pressurized while the solution is applied to prevent swelling and wall effect. This procedure also changes the structure in the column. The size of the separation effective openings can be controlled by the amount of the pressure and pores eliminated. Uniformity in the direction flow is improved by controlling polymerization with radiation rather than with conducted heat.

US Patent:

7473367, Jan 6, 2009

Filed:

Aug 10, 2005

Appl. No.:

11/200773

Inventors:

Shaofeng Xie - Lincoln NE, US

Assignee:

Dionex Corporation - Sunnyvale CA

International Classification:

B01D 15/08

US Classification:

210635, 210656, 2101982, 2105021

Abstract:

Permeable polymeric monolithic materials are prepared in a plastic column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized by the application of heat from an external source starting at a low temperature such as 40 degrees centigrade, depending on the mixture and size of the column, and continuing at a higher temperature, such as 60 degrees centigrade. The temperature at the start of the polymerization is low enough so as not to cause exothermal run-away conditions and to avoid high heat of reaction that would prevent a substantially constant temperature across the cross-section of the column. The higher temperature is used after sufficient monomer depletion has occurred and steric interference has increased so the polymerization reaction is sufficiently slow to avoid heat of reaction generation high enough to cause significant reduction in the homogeneousness of the pore sizes.

US Patent:

7922908, Apr 12, 2011

Filed:

Jan 19, 2006

Appl. No.:

11/337071

Inventors:

Robert W. Allington - Lincoln NE, US
Shaofeng Xie - Lincoln NE, US
Tao Jiang - Lincoln NE, US
Mingcheng Xu - Lincoln NE, US

Assignee:

Dionex Corporation - Sunnyvale CA

International Classification:

B01D 15/08

US Classification:

210635, 210656, 21074801, 2101982, 2105021

Abstract:

Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixture. The pressure eliminates wall effect and changes the structure in the column. Similarly, some columns that have a tendency to swell in the presence of aqueous solutions and pressurized while the solution is applied to prevent swelling and wall effect. This procedure also changes the structure in the column. The size of the separation effective openings can be controlled by the amount of the pressure and pores eliminated. Uniformity in the direction flow is improved by controlling polymerization with radiation rather than with conducted heat.

US Patent:

7922909, Apr 12, 2011

Filed:

Oct 31, 2007

Appl. No.:

11/932343

Inventors:

Robert W. Allington - Lincoln NE, US
Shaofeng Xie - Lincoln NE, US
Tao Jiang - Lincoln NE, US
Mingcheng Xu - Lincoln NE, US

Assignee:

Dionex Corporation - Sunnyvale CA

International Classification:

B01D 15/08

US Classification:

210635, 210656, 21074801, 2101982, 2105021

Abstract:

Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixture. The pressure eliminates wall effect and changes the structure in the column. Similarly, some columns that have a tendency to swell in the presence of aqueous solutions and pressurized while the solution is applied to prevent swelling and wall effect. This procedure also changes the structure in the column. The size of the separation effective openings can be controlled by the amount of the pressure and pores eliminated. Uniformity in the direction flow is improved by controlling polymerization with radiation rather than with conducted heat.

US Patent:

20040000522, Jan 1, 2004

Filed:

Jun 26, 2002

Appl. No.:

10/180350

Inventors:

Shaofeng Xie - Lincoln NE, US
Robert Allington - Lincoln NE, US

Assignee:

Isco, Inc. - Lincoln NE

International Classification:

B01D015/08

US Classification:

210/656000, 210/143000, 210/198200, 422/070000, 436/161000, 210/263000

Abstract:

Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixture. The pressure eliminates wall effect and changes the structure in the column. Similarly, some columns that have a tendency to swell in the presence of aqueous solutions and pressurized while the solution is applied to prevent swelling and wall effect. This procedure also changes the structure in the column. The size of the separation effective openings can be controlled by the amount of the pressure and pores eliminated.

US Patent:

20050061745, Mar 24, 2005

Filed:

Aug 6, 2004

Appl. No.:

10/914005

Inventors:

Shaofeng Xie - Lincoln NE, US
Mingcheng Xu - Lincoln NE, US
Robert Allington - Lincoln NE, US

Assignee:

Teledyne Isco, Inc. - Lincoln NE

International Classification:

B01D015/08

US Classification:

210656000, 210198200

Abstract:

Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials polymerized by the application of heat from an external source starting at a low temperature such as 40 degrees centigrade, depending on the mixture and size of the column, and continuing at a higher temperature, such as 60 degrees centigrade. The temperature at the start of the polymerization is low enough so as not to cause exothermal run-away conditions and to avoid high heat of reaction that would prevent a substantially constant temperature across the cross-section of the column. The higher temperature is used after sufficient monomer depletion has occurred and steric interference has increased so the polymerization reaction is sufficiently slow to avoid heat of reaction generation high enough to cause significant reduction in the homogeneousness of the pore sizes.

US Patent:

20080185327, Aug 7, 2008

Filed:

Oct 31, 2007

Appl. No.:

11/932526

Inventors:

Shaofeng Xie - Lincoln NE, US

Assignee:

Dionex Corporation - Sunnyvale CA

International Classification:

B01D 15/08
C08F 2/46

US Classification:

2101982, 521 505

Abstract:

Permeable polymeric monolithic materials are prepared in a plastic column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized by the application of heat from an external source starting at a low temperature such as 40 degrees centigrade, depending on the mixture and size of the column, and continuing at a higher temperature, such as 60 degrees centigrade. The temperature at the start of the polymerization is low enough so as not to cause exothermal run-away conditions and to avoid high heat of reaction that would prevent a substantially constant temperature across the cross-section of the column. The higher temperature is used after sufficient monomer depletion has occurred and steric interference has increased so the polymerization reaction is sufficiently slow to avoid heat of reaction generation high enough to cause significant reduction in the homogeneousness of the pore sizes.

US Patent:

20090184039, Jul 23, 2009

Filed:

Dec 30, 2008

Appl. No.:

12/346613

Inventors:

Shaofeng Xie - Lincoln NE, US

Assignee:

Dionex Corporation - Sunnyvale CA

International Classification:

B01D 15/08
C08J 5/20

US Classification:

2101982, 521 27

Abstract:

Permeable polymeric monolithic materials are prepared in a plastic column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized by the application of heat from an external source starting at a low temperature such as 40 degrees centigrade, depending on the mixture and size of the column, and continuing at a higher temperature, such as 60 degrees centigrade. The temperature at the start of the polymerization is low enough so as not to cause exothermal run-away conditions and to avoid high heat of reaction that would prevent a substantially constant temperature across the cross-section of the column. The higher temperature is used after sufficient monomer depletion has occurred and steric interference has increased so the polymerization reaction is sufficiently slow to avoid heat of reaction generation high enough to cause significant reduction in the homogeneousness of the pore sizes.