Margaux Biologics - Virtual since Jul 2011
Sr. VP Product Development
RMC Pharmaceutical Solutions since May 2003
COO
University of Colorado since Aug 1998
Adjunct Professor of Chemical Engineering
Education:
Purdue University 1984 - 1989
Worcester Polytechnic Institute 1980 - 1984
Bachelors, Bachelor of Science, Chemical Engineering
Skills:
Biotechnology Technology Transfer Validation Pharmaceutical Industry Biopharmaceuticals Chemistry Analytical Chemistry Gmp Fda Process Simulation Chromatography Protein Chemistry Drug Delivery Manufacturing Hplc Chemical Engineering Glp Quality Assurance R&D Capa Cell Culture Lifesciences Clinical Development Change Control Purification Regulatory Affairs Drug Discovery Pharmaceutics V&V Immunology Sop Commercialization Characterization Drug Development Fermentation Protein Purification Formulation Monoclonal Antibodies Molecular Biology Laboratory Microbiology Biochemistry Biochemical Engineering Process Optimization Vaccines Cell Corrective and Preventive Action Good Laboratory Practice Filtration Centrifugation
Robert Mitchiner - Longmont CO Thomas B. Kent - Boulder CO Caryn Peterson - Encinitas CA Scott Raymond Rudge - Boulder CO
Assignee:
Ferx Incorporated - San Diego CA
International Classification:
A61N 200
US Classification:
600 9
Abstract:
A magnet keeper-shield assembly adapted to hold and store a permanent magnet used to generate a high gradient magnetic field. Such a field may penetrate into deep targeted tumor sites in order to attract magnetically responsive micro-carriers. The magnet keeper-shield assembly includes a magnetically permeable keeper-shield with a bore dimensioned to hold the magnet. A screw driven actuator is used to push the magnet partially out of the keeper-shield. The actuator is assisted by several springs extending through the base of the keeper-shield.
Thomas B. Kent - Boulder CO, US Robert K. Mitchiner - Longmont CO, US Caryn Peterson - Encinitas CA, US Scott Raymond Rudge - Boulder CO, US David Glover - Agua Dulce CA, US
Assignee:
Fe Rx Incorporated - San Diego CA
International Classification:
A61N 2/00
US Classification:
600 9
Abstract:
A magnet keeper-shield assembly adapted to hold and store a permanent magnet used to generate a high gradient magnetic field that, in one embodiment, may penetrate into deep targeted tumor sites in order to attract magnetically responsive micro-carriers. The magnet keeper-shield assembly includes a magnetically permeable keeper-shield with a bore dimensioned to hold the magnet. A lever mechanism is used to push the magnet partially out of the keeper-shield. The actuator is assisted by several springs extending through the base of the keeper-shield.
Magnetically Guided Particles For Radiative Therapies
Thomas Kent - Boulder CO, US Jacqueline Johnson - Rancho Santa Fe CA, US Scott Rudge - Boulder CO, US
International Classification:
A61K051/00 A61K033/26
US Classification:
424/001110, 600/001000, 424/646000
Abstract:
Certain magnetic compositions may be used successfully for injection, followed by the application of an externally placed magnetic field that guides the particles to the targeted site, such as tissues, cells or cell components. The particles are extravasated into the targeted tissue, affording better localized distribution of the particles throughout the targeted tissue and to deeper target tissue sites. The relatively small size of the particles yields a more uniform radiative therapy, while utilizing smaller total particle mass for the procedure.
Magnetically Targetable Mitomycin C Compositions And Methods Of Their Use
Yuhua Li - Newark DE, US Caryn Peterson - Encinitas CA, US Scott Rudge - Boulder CO, US Suzanne Stevens - Longmont CO, US Gilles Tapolsky - Boulder CO, US
International Classification:
A61K 51/00 A61K 49/10 A61K 9/14 A61K 31/407
US Classification:
424001110, 424009320, 424489000, 514410000
Abstract:
The present embodiments are directed to compositions and methods of delivering the compositions that comprise mitomycin C and superior magnetically targetable carrier particles. As the compositions are magnetically targetable, their use allows the localization of mitomycin C to particular locations within a patient. This allows for an increase in the effective concentration or a decrease in systemic exposure of mitomycin C in a patient.
Robert Mitchiner - Longmont CO Thomas B. Kent - Boulder CO Caryn Peterson - Encintas CA Scott Raymond Rudge - Boulder CO
Assignee:
FeRx Incorporated - San Diego CA
International Classification:
A61N 200
US Classification:
600 9
Abstract:
A magnet keeper-shield assembly adapted to hold and store a permanent magnet used to generate a high gradient magnetic field. Such a field may penetrate into deep targeted tumor sites in order to attract magnetically responsive micro-carriers. The magnet keeper-shield assembly includes a magnetically permeable keeper-shield with a bore dimensioned to hold the magnet. A screw driven actuator is used to push the magnet partially out of the keeper-shield. The actuator is assisted by several springs extending through the base of the keeper-shield.
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Scott Rudge
Lived:
Ramona CA
Work:
Scott Lee Rudge Construction - General Building Contractor