Sai R Kumar

US Patent:

20080100796, May 1, 2008

Filed:

Oct 29, 2007

Appl. No.:

11/978336

Inventors:

John Dallas Pruitt - Suwanee GA, US
Lynn Cook Winteron - Alpharetta GA, US
Sai Ramamurthy Kumar - Johns Creek GA, US
Dawn A. Smith - Duluth GA, US

International Classification:

G02C 7/04

US Classification:

351160 H, 427164

Abstract:

The invention provides a cost-effective and in-situ method for applying an LbL coating onto a silicone hydrogel contact lens directly in a lens package. The resultant silicone hydrogel contact lens has a coating with good hydrophilicity, intactness and durability and also can be used directly from the lens package by a patient without washing and/or rising. In addition, the invention provides a packaging solution for in-situ coating of a silicone hydrogel contact lens in a lens package and an ophthalmic lens product.

US Patent:

20190290842, Sep 26, 2019

Filed:

Jun 10, 2019

Appl. No.:

16/436627

Inventors:

- Fayetteville AR, US
Greg Lamps - Smyrna GA, US
Champak Das - Fayetteville AR, US
Sai Kumar - Johns Creek GA, US
Ashley Shemain - Flowery Branch GA, US

International Classification:

A61M 5/168
F16K 99/00
F16K 31/00
F16K 17/36
A61M 39/22
A61M 5/142
F16K 7/04
F16K 11/02
F16K 31/02
F16K 11/20

Abstract:

A valve for use in connection with microfluidic devices includes a safety feature such that flow is controlled even in the case of a loss of power, thus having applications in critical applications such as the precise delivery of drugs over time. The valve may be used in connection with multiple tubes delivering drugs, and may be used with a pump, such as an electrochemical pump, to provide the force to move the fluids containing drugs for delivery. In certain applications, more than one medicine may be delivered and metered independently using a single pump with multiple reservoirs and valves.

US Patent:

20180238830, Aug 23, 2018

Filed:

Apr 19, 2018

Appl. No.:

15/957832

Inventors:

- Little Rock AR, US
Christena Nash - Roswell GA, US
Sai Kumar - Johns Creek GA, US
Timothy Muldoon - Fayetteville AR, US
Kartik Balachandran - Fayetteville AR, US
Adair Claycomb - Arlington TX, US
Matthew D. Gerner - Fayetteville AR, US
Joshua Hutcheson - Fayetteville AR, US
Foysal Z. Khan - Fayetteville AR, US
Amy Powless - Rogers AR, US
Sandra Prieto - Siloam Springs AR, US
Preston G. Scrape - Jonesboro AR, US
Melissa C. Weston - Duncan OK, US
David Parette - Fayetteville AR, US

Assignee:

BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS - Little Rock AR

International Classification:

G01N 27/447
B01L 3/00

Abstract:

A magnetohydrodynamic microfluidic system and a method of pumping a fluid using a magnetohydrodynamic system are disclosed. The method includes applying at least one of an electric current and an electric voltage to a first modified electrode and a second electrode to generate an ionic current between the first modified electrode and the second electrode and to cause a current carrying species to move to or from the modified electrode, applying a magnetic field perpendicular to an ionic current vector, the magnetic field and the ionic current combining to induce flow of the fluid in a direction perpendicular to the magnetic field and the ionic current vector, and maintaining fluid flow by recharging the modified electrode.

US Patent:

20170224918, Aug 10, 2017

Filed:

Aug 14, 2015

Appl. No.:

15/503310

Inventors:

- Fayetteville AR, US
Greg Lamps - Smyrna GA, US
Champak Das - Fayetteville AR, US
Sai Kumar - Johns Creek GA, US
Ashley Shemain - Flowery Branch GA, US

International Classification:

A61M 5/168
A61M 39/22
F16K 99/00
F16K 31/00
F16K 17/36

Abstract:

A valve for use in connection with microfluidic devices includes a safety feature such that flow is controlled even in the case of a loss of power, thus having applications in critical applications such as the precise delivery of drugs overtime. The valve may be used in connection with multiple tubes delivering drugs, and may be used with a pump, such as an electrochemical pump, to provide the force to move the fluids containing drugs for delivery. In certain applications, more than one medicine may be delivered and metered independently using a single pump with multiple reservoirs and valves.

US Patent:

20160146756, May 26, 2016

Filed:

Nov 24, 2015

Appl. No.:

14/951322

Inventors:

- Little Rock AR, US
Christena Nash - Roswell GA, US
Sai Kumar - Johns Creek GA, US
Timothy Muldoon - Fayetteville AR, US
Kartik Balachandran - Fayetteville AR, US
Adair Claycomb - Arlington TX, US
Matthew D. Gerner - Fayetteville AR, US
Joshua Hutcheson - Fayetteville AR, US
Foysal Z. Khan - Fayetteville AR, US
Amy Powless - Rogers AR, US
Sandra Prieto - Siloam Springs AR, US
Preston G. Scrape - Jonesboro AR, US
Melissa C. Weston - Duncan OK, US

International Classification:

G01N 27/447
G01N 15/14
B01L 3/00

Abstract:

A magnetohydrodynamic microfluidic system and a method of pumping a fluid using a magnetohydrodynamic system are disclosed. The method includes applying at least one of an electric current and an electric voltage to a first modified electrode and a second electrode to generate an ionic current between the first modified electrode and the second electrode and to cause a current carrying species to move to or from the modified electrode, applying a magnetic field perpendicular to an ionic current vector, the magnetic field and the ionic current combining to induce flow of the fluid in a direction perpendicular to the magnetic field and the ionic current vector, and maintaining fluid flow by recharging the modified electrode.

US Patent:

20150258273, Sep 17, 2015

Filed:

Aug 29, 2012

Appl. No.:

13/598351

Inventors:

Forrest W. Payne - Fayetteville AR, US
Sai Ramamurthy Kumar - Johns Creek GA, US
Christine E. Evans - North Liberty IA, US
Anna Washburn - Elkins AR, US
Andy M. Dunn - Santa Monica CA, US
Brian Young - Bloomington IN, US
Joe Bruton - Fayetteville AR, US
Champak Das - Fayetteville AR, US
Kavita M. Jeerage - Denver CO, US
Carl A. Koval - Arvada CO, US
Richard D. Noble - Boulder CO, US

International Classification:

A61M 5/142
F15C 3/04
A61M 5/145

Abstract:

Electrochemical actuation is disclosed for fluid movement and flow control in microfluidic devices, allowing for miniaturization, minimal power requirements, single-use disposability and engineering of small, complex fluidic networks. In one embodiment, a single-dose fluid delivery device is operable to deliver a bolus dose, in a single extended stroke or in multiple repeated doses. The device uses three electrochemically-actuated chambers, two of the chambers operating as inlet/outlet valves for the device and a third providing both a temporary containment and pumping action. By sequential manipulation of the fluid pressure in the three chambers, fluids may be delivered in precise quantities by the device.

US Patent:

20150224499, Aug 13, 2015

Filed:

Feb 13, 2015

Appl. No.:

14/622411

Inventors:

- Fayetteville AR, US
Champak Das - Fayetteville AR, US
Bradley Ledden - Fayetteville AR, US
Qian Sun - Fayetteville AR, US
Chien Nguyen - Fayetteville AR, US
Sai Kumar - Johns Creek GA, US

International Classification:

B01L 3/00
G01N 33/53

Abstract:

An automated assay platform for determining the presence and/or amount of analytes of interest in a sample at point of care integrates microfluidic enhanced assay sites, disposable cartridge designs, a sensitive low-volume detection module, together with selected pumping and valving modules, customized control board and user friendly graphical user interface (GUI). Comparing to traditional assay platform like 96-well ELISA, the platform is capable of reducing reagent consumption, increasing assay speed, and enhancing assay performance with a sample-in-answer-out automated process. This platform also features flexibility of adapting different assay schemes for different analytes.