Roland Luet Roland Luethy from Concord, CA, age 66

Secreted Epithelial Colon Stromal-1 Molecules And Uses Thereof
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US Patent:

7329729, Feb 12, 2008
Filed:

Nov 28, 2000
Appl. No.:

09/724000
Inventors:

Anthony J. Polverino - Thousand Oaks CA, US
Roland Luethy - Newbury Park CA, US
Assignee:

Amgen Inc. - Thousand Oaks CA
International Classification:

C07K 14/435
US Classification:

530350, 536 235
Abstract:

The present invention provides novel Secreted Epithelial Colon Stromal-1 (Secs-1) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing Secs-1 polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with Secs-1 polypeptides.

Secreted Epithelial Colon Stromal-1 Molecules And Uses Thereof
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US Patent:

7629144, Dec 8, 2009
Filed:

Feb 28, 2006
Appl. No.:

11/364871
Inventors:

Anthony J. Polverino - Bainbridge Island WA, US
Roland Luethy - Camarillo CA, US
Assignee:

Amgen Inc. - Thousand Oaks CA
International Classification:

C12P 21/06
US Classification:

435 691, 536 231, 536 235, 530300, 530350, 4353201, 435325
Abstract:

The present invention provides novel Secreted Epithelial Colon Stromal-1 (Secs-1) polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, selective binding agents, and methods for producing Secs-1 polypeptides. The invention further provides methods for the treatment, diagnosis, amelioration, or prevention of diseases associated with Secs-1 polypeptides.

Tnfr/Opg-Like Molecules And Uses Thereof
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US Patent:

20030077246, Apr 24, 2003
Filed:

May 15, 2002
Appl. No.:

10/146574
Inventors:

Andrew Welcher - Ventura CA, US
Gary Fox - Newbury Park CA, US
Michael Boedigheimer - Newbury Park CA, US
Junyan Shu - Thousand Oaks CA, US
Shuqian Jing - Thousand Oaks CA, US
Brian Bennett - Thousand Oaks CA, US
Roland Luethy - Camarillo CA, US
International Classification:

C07K014/715
A61K038/19
C07H021/04
C12P021/02
C12N005/06
US Classification:

424/085100, 435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:

The present invention provides novel TNFr/OPG-like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, antibodies, and methods for producing TNFr/OPG-like polypeptides. Also provided for are methods for the diagnosis and treatment of diseases with TNFr/OPG-like polypeptides.

Methods Of Modulating Appetite Using Agouti-Related Transcript Polypeptides
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US Patent:

20030082737, May 1, 2003
Filed:

Sep 27, 2002
Appl. No.:

10/256590
Inventors:

Kevin Stark - Newbury Park CA, US
Roland Luethy - Newbury Park CA, US
Assignee:

Amgen Inc.
International Classification:

C12P021/02
C12N005/06
C07K014/705
C07H021/04
US Classification:

435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:

Disclosed is a novel gene termed ART which is expressed primarily in selected regions of the brain, as well as adrenal and lung tissues. Polypeptides encoded by ART are also disclosed, as are methods for preparing ART DNA and amino acid sequences.

Interleukin-1 Receptor Antagonist-Like Molecules And Uses Thereof
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US Patent:

20030166069, Sep 4, 2003
Filed:

May 6, 2002
Appl. No.:

10/139947
Inventors:

Andrew Welcher - Ventura CA, US
Roland Luethy - Newbury Park CA, US
Shuqian Jing - Thousand Oaks CA, US
Assignee:

Amgen, Inc.
International Classification:

C07K014/715
C07H021/04
C12N009/99
C12P021/02
C12N005/06
US Classification:

435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:

The present invention provides novel Interleukin-1 Receptor Antagonist-Like (IL-1ra-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IL-1ra-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IL-1ra-L polypeptides.

Nucleic Encoding Interleukin-1 Receptor Antagonist-Like Proteins And Uses Thereof
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US Patent:

20040208872, Oct 21, 2004
Filed:

Dec 12, 2003
Appl. No.:

10/735354
Inventors:

Andrew Welcher - Ventura CA, US
Roland Luethy - Newbury Park CA, US
Shuqian Jing - Thousand Oaks CA, US
Assignee:

Amgen, Inc., A Corporation of the State of Delaware
International Classification:

A61K039/395
C07H021/04
C07K014/47
US Classification:

424/145100, 435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:

The present invention provides novel Interleukin-1 Receptor Antagonist-Like (IL-1ra-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IL-1ra-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IL-1ra-L polypeptides.

Nucleic Encoding Interleukin-1 Receptor Antagonist-Like Proteins And Uses Thereof
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US Patent:

20050123512, Jun 9, 2005
Filed:

Dec 12, 2003
Appl. No.:

10/735420
Inventors:

Frank Calzone - Westlake Village CA, US
Roland Luethy - Newbury Park CA, US
Michael Boedigheimer - Newbury Park CA, US
Jun Zhu - Newbury Park CA, US
Young-ah Chung - Thousand Oaks CA, US
Shuqian Jing - Thousand Oaks CA, US
International Classification:

A61K048/00
C07H021/04
C07K014/715
C12N015/86
US Classification:

424093200, 435069100, 435320100, 435325000, 435456000, 530350000, 536023500
Abstract:

The present invention provides novel Interleukin-1 Receptor Antagonist-Like (IL-1ra-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IL-1ra-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IL-1ra-L polypeptides.

Tnfr/Opg-Like Molecules And Uses Thereof
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US Patent:

20060024267, Feb 2, 2006
Filed:

Jan 25, 2005
Appl. No.:

11/042814
Inventors:

Andrew Welcher - Ventura CA, US
Gary Fox - Newbury Park CA, US
Michael Boedigheimer - Newbury Park CA, US
Junyan Shu - Thousand Oaks CA, US
Shuqian Jing - Thousand Oaks CA, US
Brian Bennett - Thousand Oaks CA, US
Roland Luethy - Camarillo CA, US
International Classification:

A61K 38/19
A61K 38/17
US Classification:

424085100, 514012000
Abstract:

The present invention provides novel TNFr/OPG-like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, antibodies, and methods for producing TNFr/OPG-like polypeptides. Also provided for are methods for the diagnosis and treatment of diseases with TNFr/OPG-like polypeptides.