Roger R Labrecque

Author:

Roger Labrecque

ISBN #:

2980673110

US Patent:

6616876, Sep 9, 2003

Filed:

Oct 3, 2000

Appl. No.:

09/678765

Inventors:

Roger Labrecque - Dracut MA
Joseph Ferraro - Londonderry NH
Tom Swanick - Nashua NH
Paul Martakos - Pelham NH

Assignee:

Atrium Medical Corporation - Hudson NH

International Classification:

B29B 1110

US Classification:

264119, 264109, 264126, 264127, 264134, 264291, 264343

Abstract:

The invention is directed to methods involving rewetting of expandable polymers with a wettable liquid to allow for enhanced expansion at or below room temperature without breakage, and in some cases, allows one to achieve a greater expansion ratio than that allowed at elevated temperatures using known methods. The present invention also allows one to achieve material with unique properties and handling characteristics. These properties included decreased material thickness, increased density, an altered node/fibril morphology, and a more consistent web in the case of flat material. This method is not limited to room temperature conditions and can be applied whenever the expandable polymer material is wet with a wettable liquid, and the expansion is performed at a temperature preferably below the vaporization or boiling points of that liquid.

US Patent:

6890463, May 10, 2005

Filed:

Apr 22, 2002

Appl. No.:

10/131446

Inventors:

Paul Martakos - Pelham NH, US
Roger Labrecque - Londonderry NH, US
Geoffrey Moodie - Nashua NH, US
Steve A. Herweck - Nashua NH, US
Theodore Karwoski - Hollis NH, US

Assignee:

Atrium Medical Corporation - Hudson NH

International Classification:

B29B011/10
B29B011/14
B29B013/00
B29B013/02
B29B015/00

US Classification:

264119, 264122, 264123, 264126, 264120, 264241, 264291

Abstract:

The invention is directed to methods involving rewetting of expandable polymers with a wettable liquid to allow for enhanced expansion at or below room temperature without breakage, and in some cases, allows one to achieve a greater expansion ratio than that allowed at elevated temperatures using known methods. The wettable liquid can be formed of a drug and/or an agent, such that the resulting polymer contains and emits the drug upon positioning at a target location of a patient body. The present invention also allows one to achieve material with unique properties and handling characteristics. These properties included decreased material thickness, increased density, an altered node/fibril morphology, and a more consistent web in the case of flat material. This method is not limited to room temperature conditions and can be applied whenever the expandable polymer material is wet with a wettable liquid, and the expansion is performed at a temperature preferably below the vaporization or boiling points of that liquid.

US Patent:

6923927, Aug 2, 2005

Filed:

Mar 23, 2004

Appl. No.:

10/807709

Inventors:

Paul Martakos - Pelham NH, US
Roger Labrecque - Londonderry NH, US
Geoffrey Moodie - Hudson NH, US
Steve A. Herweck - Nashua NH, US
Theodore Karwoski - Hollis NH, US

Assignee:

Atrium Medical Corporation - Hudson NH

International Classification:

B29B011/10
B29B011/14
B29B013/00
B29B013/02
B29B015/00

US Classification:

264119, 264122, 264123, 264126, 264120, 264241, 264291

Abstract:

The invention is directed to methods involving rewetting of expandable polymers with a wettable liquid to allow for enhanced expansion at or below room temperature without breakage, and in some cases, allows one to achieve a greater expansion ratio than that allowed at elevated temperatures using known methods. The wettable liquid can be formed of a drug and/or an agent, such that the resulting polymer contains and emits the drug upon positioning at a target location of a patient body. The expandable polymer can also have the drug or agent added to its structure at a polymer resin preparation stage, through use of an aqueous solution mixed with one or more fluoropolymers, or in a mixing stage. The present invention also allows one to achieve material with unique properties and handling characteristics. These properties included decreased material thickness, increased density, an altered node/fibril morphology, and a more consistent web in the case of flat material.

US Patent:

7572245, Aug 11, 2009

Filed:

Sep 15, 2004

Appl. No.:

10/942764

Inventors:

Steve A. Herweck - Nashua NH, US
Paul Martakos - Pelham NH, US
Geoffrey Moodie - Hudson NH, US
Roger Labrecque - Londonderry NH, US
Theodore Karwoski - Hudson NH, US
Trevor Carlton - Hudson NH, US

Assignee:

Atrium Medical Corporation - Hudson NH

International Classification:

A61M 31/00

US Classification:

60410302

Abstract:

A non-polymeric or biological coating applied to radially expandable interventional medical devices provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device. Thus, atraumatic local tissue transference delivery is achieved for uniform therapeutic agent distribution and controlled bio-absorption into the tissue after placement within a patient's body with a non-inflammatory coating.

US Patent:

7947015, May 24, 2011

Filed:

May 18, 2007

Appl. No.:

11/804478

Inventors:

Steve A. Herweck - Nashua NH, US
Paul Martakos - Pelham NH, US
Geoffrey Moodie - Hudson NH, US
Roger Labrecque - Londonderry NH, US
Theodore Karwoski - Hollis NH, US
Trevor Carlton - Hudson NH, US

Assignee:

Atrium Medical Corporation - Hudson NH

International Classification:

A61M 37/00

US Classification:

60410302

Abstract:

A non-polymeric or biological coating applied to radially expandable medical delivery device provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The delivery device is expanded using the pressure of an inflation fluid. After expanding the delivery device to a pre-determined size and shape, the inflation fluid weeps through the porous surface of the delivery device. The coating releases the delivery device and floats on the inflation fluid until bonding to the tissue due to its affinity for the tissue. Once the coating bonds or affixes to the tissue, through an absorption mechanism by the tissue cells of the coating material, the coating and any therapeutics contained therein are delivered to the tissue. The fluid can contain a therapeutic agent, or can be otherwise biocompatible and/or inert.

US Patent:

8001922, Aug 23, 2011

Filed:

Sep 28, 2005

Appl. No.:

11/238554

Inventors:

Roger Labrecque - Londonderry NH, US
Geoffrey Moodie - Hudson NH, US
Joseph Ferraro - Londonderry NH, US
Lisa Rogers - Londonderry NH, US
Paul Martakos - Pelham NH, US
Theodore Karwoski - Hudson NH, US
Steve A. Herweck - Nashua NH, US
Suzanne Conroy - Dracut MA, US
Brian Sunter - Londonderry NH, US
Georgette Henrich - Dracut MA, US

Assignee:

Atrium Medical Corporation - Hudson NH

International Classification:

B05C 1/00

US Classification:

118200, 427 21, 427 224

Abstract:

Devices for the provision of a coating on an implantable medical device are provided. The coating includes a bio-absorbable carrier component. In addition to the bio-absorbable carrier component, a therapeutic agent component can also be provided. The devices provide a coating having improved uniformity and coverage which in turn allow for greater control of the amount and dosage of the coating.

US Patent:

8021331, Sep 20, 2011

Filed:

Oct 14, 2005

Appl. No.:

11/250768

Inventors:

Steve A. Herweck - Nashua NH, US
Paul Martakos - Pelham NH, US
Geoffrey Moodie - Hudson NH, US
Roger Labrecque - Londonderry NH, US
Theodore Karwoski - Hollis NH, US
Trevor Carlton - Hudson NH, US
Lisa Rogers - Londonderry NH, US
Joseph Ferraro - Londonderry NH, US

Assignee:

Atrium Medical Corporation - Hudson NH

International Classification:

A61M 37/00
A61M 31/00

US Classification:

60410308, 60410302

Abstract:

A non-polymeric or biological coating applied to a radially expandable interventional medical device in a collapsed, wrapped, or folded configuration. Properties of the coating material applied to the medical device are adjusted or varied to result in a desired combination of coverage of the surface of the medical device, drug loading, and coating thickness. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device.

US Patent:

8263102, Sep 11, 2012

Filed:

Sep 28, 2005

Appl. No.:

11/236908

Inventors:

Roger Labrecque - Londonderry NH, US
Geoffrey Moodie - Hudson NH, US
Joseph Ferraro - Londonderry NH, US
Lisa Rogers - Londonderry NH, US
Paul Martakos - Pelham NH, US
Theodore Karwoski - Hollis NH, US
Steve A. Herweck - Nashua NH, US

Assignee:

Atrium Medical Corporation - Hudson NH

International Classification:

A61F 2/00
A61K 9/00

US Classification:

424423, 424484, 424425, 424426

Abstract:

A coated medical device an a method of providing a coating on an implantable medical device result in a medical device having a bio-absorbable coating. The coating includes a bio-absorbable carrier component. In addition to the bio-absorbable carrier component, a therapeutic agent component can also be provided. The coated medical device is implantable in a patient to effect controlled delivery of the coating, including the therapeutic agent, to the patient.