Rodolfo Morales

Author:

Rodolfo Morales

ISBN #:

0892391219

Author:

Rodolfo Morales

ISBN #:

0892391499

Author:

Rodolfo Morales

ISBN #:

0892391561

US Patent:

7534204, May 19, 2009

Filed:

Aug 27, 2004

Appl. No.:

10/927784

Inventors:

Niel F. Starksen - Los Altos Hills CA, US
Nick Pliam - Kent CT, US
Rodolfo A. Morales - Los Gatos CA, US
John To - Newark CA, US

Assignee:

Guided Delivery Systems, Inc. - Santa Clara CA

International Classification:

A61B 1/00

US Classification:

600116, 600129, 600182

Abstract:

Devices and methods for facilitating transvascular, minimally invasive and other “less invasive” surgical procedures generally include a sheath with an expandable balloon at the distal end, an inflation lumen for expanding the balloon, and a device passage lumen for allowing passage of one or more surgical instruments. The sheath is configured to house at least one visualization device such that an optical element of the device is positioned to view the surgical site. In some embodiments, instruments may be passed through the sheath, with the distal balloon partially or fully circumscribing or encircling the instruments. Any suitable instrument(s) may be passed through sheaths of the invention, such as a surgical clip applier for repairing a heart valve, an ablation member for treating atrial fibrillation, one or more pacemaker leads, a coronary sinus access device or the like.

US Patent:

7588582, Sep 15, 2009

Filed:

Oct 20, 2005

Appl. No.:

11/255400

Inventors:

Niel F. Starksen - Los Altos Hills CA, US
John To - Newark CA, US
Rodolfo A. Morales - Los Gatos CA, US

Assignee:

Guided Delivery Systems Inc. - Santa Clara CA

International Classification:

A61F 2/24

US Classification:

606139, 623 211

Abstract:

Described herein are methods of remodeling the base of a ventricle. In particular, methods of remodeling a valve annulus by forming a new fibrous annulus are described. These methods may result in a remodeled annulus that corrects valve leaflet function without substantially inhibiting the mobility of the leaflet. The methods of remodeling the base of the ventricle include the steps of securing a plurality of anchors to the valve annulus beneath one or more leaflets of the valve, constricting the valve annulus by cinching a tether connecting the anchors, and securing the anchors in the cinched conformation to allow the growth of fibrous tissue. The annulus may be cinched (e. g. , while visualizing the annulus) so that the mobility of the valve leaflets is not significantly restricted. The remodeled annulus is typically constricted to shorten the diameter of the annulus to correct for valve dysfunction (e. g. , regurgitation).

US Patent:

7666193, Feb 23, 2010

Filed:

Jul 27, 2004

Appl. No.:

10/901555

Inventors:

Niel F. Starksen - Los Altos Hills CA, US
John To - Newark CA, US
Mariel Fabro - San Jose CA, US
Michael F. Wei - Redwood City CA, US
Rodolfo A. Morales - Los Gatos CA, US

Assignee:

Guided Delivery Sytems, Inc. - Santa Clara CA

International Classification:

A61B 17/10

US Classification:

606142, 623 211

Abstract:

Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contacting the anchor delivery device with a length of the valve annulus, delivering a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus, and drawing the anchors together to circumferentially tighten the valve annulus. Devices generally include an elongate catheter having at least one tensioning member and at least one tensioning actuator for deforming a distal portion of the catheter to help it conform to a valve annulus. The catheter device may be used to navigate a subannular space below a mitral valve to facilitate positioning of an anchor delivery device.

US Patent:

7753858, Jul 13, 2010

Filed:

Jul 27, 2004

Appl. No.:

10/901455

Inventors:

Niel F. Starksen - Los Altos Hills CA, US
John To - Newark CA, US
Mariel Fabro - San Jose CA, US
Michael F. Wei - Menlo Park CA, US
Rodolfo A. Morales - Los Gatos CA, US

Assignee:

Guided Delivery Systems, Inc. - Santa Clara CA

International Classification:

A61M 25/00
A61M 1/00
A61M 31/00
A61M 37/00
A61M 5/178

US Classification:

600585, 604 27, 604 28, 604 48, 604500, 604506, 604507, 604508, 604510, 604 9301, 60416401, 60416413

Abstract:

Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contacting the anchor delivery device with a length of the valve annulus, delivering a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus, and drawing the anchors together to circumferentially tighten the valve annulus. Devices generally include an elongate catheter having at least one tensioning member and at least one tensioning actuator for deforming a distal portion of the catheter to help it conform to a valve annulus. The catheter device may be used to navigate a subannular space below a mitral valve to facilitate positioning of an anchor delivery device.

US Patent:

7753924, Jul 13, 2010

Filed:

Jul 27, 2004

Appl. No.:

10/901444

Inventors:

Niel F. Starksen - Los Altos Hills CA, US
John To - Newark CA, US
Mariel Fabro - San Jose CA, US
Michael F. Wei - Redwood City CA, US
Rodolfo A. Morales - Los Gatos CA, US

Assignee:

Guided Delivery Systems, Inc. - Santa Clara CA

International Classification:

A61B 17/08

US Classification:

606151

Abstract:

Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contacting the anchor delivery device with a length of the valve annulus, delivering a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus, and drawing the anchors together to circumferentially tighten the valve annulus. Devices generally include an elongate catheter having at least one tensioning member and at least one tensioning actuator for deforming a distal portion of the catheter to help it conform to a valve annulus. The catheter device may be used to navigate a subannular space below a mitral valve to facilitate positioning of an anchor delivery device.

US Patent:

7758637, Jul 20, 2010

Filed:

Jul 27, 2004

Appl. No.:

10/901019

Inventors:

Niel F. Starksen - Los Altos Hills CA, US
John To - Newark CA, US
Rodolfo A. Morales - Los Gatos CA, US

Assignee:

Guided Delivery Systems, Inc. - Santa Clara CA

International Classification:

A61F 2/24

US Classification:

623 211, 606144, 606151

Abstract:

Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contacting the anchor delivery device with a length of the valve annulus, delivering a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus, and drawing the anchors together to circumferentially tighten the valve annulus. Devices generally include an elongate catheter having at least one tensioning member and at least one tensioning actuator for deforming a distal portion of the catheter to help it conform to a valve annulus. The catheter device may be used to navigate a subannular space below a mitral valve to facilitate positioning of an anchor delivery device.

US Patent:

8343173, Jan 1, 2013

Filed:

Jun 4, 2008

Appl. No.:

12/133319

Inventors:

Niel F. Starksen - Los Altos Hills CA, US
John To - Newark CA, US
Mariel Fabro - San Jose CA, US
Michael F. Wei - Redwood City CA, US
Rodolfo A. Morales - Los Gatos CA, US

Assignee:

Guided Delivery Systems Inc. - Santa Clara CA

International Classification:

A61B 17/08

US Classification:

606151

Abstract:

Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contacting the anchor delivery device with a length of the valve annulus, delivering a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus, and drawing the anchors together to circumferentially tighten the valve annulus. Devices generally include an elongate catheter having at least one tensioning member and at least one tensioning actuator for deforming a distal portion of the catheter to help it conform to a valve annulus. The catheter device may be used to navigate a subannular space below a mitral valve to facilitate positioning of an anchor delivery device.

US Patent:

20040243227, Dec 2, 2004

Filed:

Mar 2, 2004

Appl. No.:

10/792681

Inventors:

Niel Starksen - Los Altos Hills CA, US
John To - Newark CA, US
Rodolfo Morales - Los Gatos CA, US

Assignee:

Guided Delivery Systems, Inc. - Los Altos CA

International Classification:

A61F002/24

US Classification:

623/002110, 623/002360

Abstract:

Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contacting the anchor delivery device with a length of the valve annulus, delivering a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus, and drawing the anchors together to circumferentially tighten the valve annulus. Devices generally include an elongate catheter having at least one tensioning member and at least one tensioning actuator for deforming a distal portion of the catheter to help it conform to a valve annulus. The catheter device may be used to navigate a subannular space below a mitral valve to facilitate positioning of an anchor delivery device.