Robert A Williamson

Author:

Robert B. Williamson

ISBN #:

0844720518

Author:

Robert Clifford Williamson

ISBN #:

0306443244

Author:

Robert Clifford Williamson

ISBN #:

0471949051

Author:

Robert Clifford Williamson

ISBN #:

0875812643

Author:

Robert Clifford Williamson

ISBN #:

9027930686

Author:

Robert W. Williamson

ISBN #:

0404141838

Author:

Robert W. Williamson

ISBN #:

0404142419

Author:

Robert W. Williamson

ISBN #:

0404143008

US Patent:

6760455, Jul 6, 2004

Filed:

Jul 13, 2001

Appl. No.:

09/905634

Inventors:

Robert C. Williamson - La Jolla CA

Assignee:

American Technology Corporation - San Diego CA

International Classification:

H04R 2500

US Classification:

381191, 381190, 381173

Abstract:

An electrostatic loudspeaker includes a high resistivity stator with electrode conductivity per square that is constant and/or decreases with distance from the connection point. A contact area of predetermined size is related to the highest frequency of interest. The constant or decreasing surface resistivity of the stators, interacting with the capacitive load of the stator to stator gap, operates as a distributed network such that the active acoustic output is attenuated in a predetermined manner with increased frequency at all points equidistant on the stator from the connection area. The apparent acoustic source size is reduced as the frequency increases to maintain enhanced dispersion across the operating range of the loudspeaker system.

US Patent:

8568719, Oct 29, 2013

Filed:

Aug 13, 2010

Appl. No.:

12/806498

Inventors:

Robert Anthony Williamson - La Jolla CA, US
Jehangir Wadia - San Diego CA, US
Gabriel Pascual - La Jolla CA, US
Elissa Keogh - San Diego CA, US

Assignee:

Crucell Holland B.V. - Leiden

International Classification:

A61K 39/395

US Classification:

4241331, 5303871

Abstract:

Provided herein are antibodies or antigen-binding fragments thereof that immunospecifically bind to the fusion (F) protein of Respiratory Syncytial Virus (RSV). Also provided are methods for of prevention, treatment and diagnosis of viral infection and/or the treatment of one more symptoms of RSV-mediated disease. Methods of generating antibodies that immunospecifically bind RSV F protein also are provided.

US Patent:

20100081575, Apr 1, 2010

Filed:

Sep 18, 2009

Appl. No.:

12/586273

Inventors:

Robert Anthony Williamson - La Jolla CA, US
Jehangir Wadia - San Diego CA, US
Toshiaki Maruyama - La Jolla CA, US
Zhifeng Chen - Vista CA, US
Joshua Nelson - La Jolla CA, US

International Classification:

C40B 10/00
C40B 40/06
C40B 40/10
C40B 50/00
C40B 50/06

US Classification:

506 1, 506 16, 506 18, 506 23, 506 26

Abstract:

Provided herein are methods for generating diverse polypeptide and nucleic acid molecule libraries and collections, and the collections and libraries; methods for selecting variant polypeptides and nucleic acid molecules from the libraries; and molecules selected from the libraries. Exemplary of the polypeptides and nucleic acid molecules are antibodies and nucleic acids encoding the antibodies (including antibody fragments and domain exchanged antibodies). Also provided herein are methods of displaying polypeptides such as antibodies, for example on the surface of genetic packages, such as phage; and libraries and collections of the displayed polypeptides and vectors for producing the displayed polypeptides, libraries and collections. Exemplary of the displayed antibodies are domain exchanged antibodies.

US Patent:

20100093563, Apr 15, 2010

Filed:

Sep 18, 2009

Appl. No.:

12/586307

Inventors:

Robert Anthony Williamson - La Jolla CA, US
Jehangir Wadia - San Diego CA, US
Toshiaki Maruyama - La Jolla CA, US
Zhifeng Chen - Vista CA, US
Joshua Nelson - La Jolla CA, US

International Classification:

C40B 40/08
C07K 19/00
C12N 15/63
C07H 21/04

US Classification:

506 17, 5303911, 4353201, 536 2353, 435 697

Abstract:

Provided herein are methods for generating diverse polypeptide and nucleic acid molecule libraries and collections, and the collections and libraries; methods for selecting variant polypeptides and nucleic acid molecules from the libraries; and molecules selected from the libraries. Exemplary of the polypeptides and nucleic acid molecules are antibodies and nucleic acids encoding the antibodies (including antibody fragments and domain exchanged antibodies). Also provided herein are methods of displaying polypeptides such as antibodies, for example on the surface of genetic packages, such as phage; and libraries and collections of the displayed polypeptides and vectors for producing the displayed polypeptides, libraries and collections. Exemplary of the displayed antibodies are domain exchanged antibodies.

US Patent:

20110033389, Feb 10, 2011

Filed:

Apr 29, 2010

Appl. No.:

12/799746

Inventors:

Zhifeng Chen - Vista CA, US
Jehangir Wadia - San Diego CA, US
Robert Anthony Williamson - La Jolla CA, US

International Classification:

A61K 39/42
C07K 19/00
G01N 33/566
C12N 15/63
C07H 21/00
C12N 5/10
C12P 21/02
C07K 7/06
A61P 31/22
A61P 31/12
A61K 49/00

US Classification:

424 96, 5303873, 435 71, 4241341, 4353201, 536 2353, 435328, 435 696, 530327, 530328, 424 91

Abstract:

Provided herein are modified therapeutic antibodies containing a protein transduction domain conjugated to a neutralizing antibody. Also provided are methods for generating the modified therapeutic antibodies and methods of using the modified therapeutic antibodies for prevention and treatment of disease.

US Patent:

20110189183, Aug 4, 2011

Filed:

Sep 17, 2010

Appl. No.:

12/807955

Inventors:

Robert Anthony Williamson - La Jolla CA, US
Jehangir Wadia - San Diego CA, US
Michelle Wagner - San Diego CA, US

International Classification:

A61K 39/395
C12N 15/63
C07K 16/14
C07H 21/00
C12N 1/00
C12N 5/10
A61P 31/10

US Classification:

4241351, 4353201, 5303891, 5303873, 5303911, 4241721, 4241331, 536 2353, 435243, 435419, 435325

Abstract:

Provided herein are antibodies that immunospecifically bind to species of the genus . Also provided are methods for of prevention, treatment and diagnosis of infection and/or the treatment of one more symptoms of infection. Methods of generating antibodies that immunospecifically bind also are provided.

US Patent:

20120165512, Jun 28, 2012

Filed:

May 4, 2010

Appl. No.:

13/318805

Inventors:

Claire Abadie - Annecy, FR
Jean-Marc Combette - Saint-Cergues, FR
Catherine Deloche - Geneva, CH
Robert Anthony Williamson - La Jolla CA, US

Assignee:

RIBOVAX BIOTECHNOLOGIES S.A. - Petit-Lancy (Geneva)

International Classification:

C07K 16/00
C07K 16/08

US Classification:

5303894, 5303871, 5303913

Abstract:

The present invention relates to the use of a fully human antigen binding fragment of an antibody for the manufacture of a medicament for the treatment or diagnosis of an ocular disease upon topical administration. The invention further relates to a pharmaceutical composition for ocular topical administration for treatment or diagnosis of an ocular disease comprising a fully human binding fragment of an antibody. In particular, the antibody neutralises HSV1 and HSV2.

US Patent:

20130177573, Jul 11, 2013

Filed:

Jul 8, 2011

Appl. No.:

13/809397

Inventors:

Robert Anthony Williamson - La Jolla CA, US
Jehangir Wadia - San Diego CA, US
Gabriel Pascual - La Jolla CA, US
Elissa Keogh - San Diego CA, US

International Classification:

C07K 16/10

US Classification:

4241591, 5303894, 5303873, 435 5, 536 2353

Abstract:

Provided herein are antibodies or antigen-binding fragments thereof that immunospecifically bind to the fusion (F) protein of Respiratory Syncytial Virus (RSV). Also provided are methods for of prevention, treatment and diagnosis of viral infection and/or the treatment of one more symptoms of RSV-mediated disease. Methods of generating antibodies that immunospecifically bind RSV F protein also are provided.