Robert W Lathrop

US Patent:

20060078599, Apr 13, 2006

Filed:

Oct 12, 2004

Appl. No.:

10/962989

Inventors:

Mathew Ebmeier - Fort Collins CO, US
Robert Lathrop - Fort Collins CO, US

International Classification:

A61K 36/14
A61K 31/717
A61K 31/137
A61K 31/045
A61K 31/125

US Classification:

424443000, 514057000, 514649000, 424770000, 514729000, 514692000, 514730000, 514731000, 424725100

Abstract:

The present invention provides a non-water soluble, film-forming composition which adheres to body tissue and forms a pharmaceutical carrier to provide localized delivery of an antifungal agent to a treatment site. The composition will typically include: (a) an alkyl cellulose; (b) a hydroxyalkyl cellulose; (c) a pharmaceutically acceptable polar protic solvent; (d) an antifungal agent selected from the group of naftifine, ciclopirox, terbinafine, pharmaceutically acceptable salts thereof, and combinations thereof; (e) an glycol ether; (f) an antipruritic agent selected from the group of camphor, menthol, butamben picrate, metacresol, benzyl alcohol, camphorated metacresol, juniper tar, phenol, phenolate sodium, resorcinol, camphorated metacresol, carbolic acid, and combinations,; and (g) a solubility enhancing agent, a surfactant, a wetting agent, or a combination thereof. The present invention also provides for the use of the composition composition of the present invention, in treating a fungal infection (e.g., nail fungus) in a mammal afflicted with such an infection.

US Patent:

20060204526, Sep 14, 2006

Filed:

Feb 13, 2006

Appl. No.:

11/352935

Inventors:

Robert Lathrop - Fort Collins CO, US
David Osborne - Santa Rosa CA, US

International Classification:

A61K 9/00
A61K 31/135

US Classification:

424400000, 514646000

Abstract:

The present invention relates to a topical, emulsive composition containing Dapsone or its derivative. The inventive composition incorporates emollients and Dapsone or its derivative in a stable emulsion. The stability is achieved through the use of a combination of certain surfactant mixtures and an enhancer providing solubility of the Dapsone.

US Patent:

20200054552, Feb 20, 2020

Filed:

Aug 19, 2019

Appl. No.:

16/543763

Inventors:

- Planegg/Martinsried, DE
Robert LATHROP - Fort Collins CO, US
Erwin BOHM - Ladenburg, DE
Irene GANDER-MEISTERERNST - Stockdorf, DE
Regina GREGER - Iffeldorf, DE
Johanna HOLLDACK - Aarhus C, DK
Ulrich MOEBIUS - Gauting-Unterbrunn, DE

International Classification:

A61K 9/00
A61K 47/14
A61K 47/10
A61K 47/06
A61K 31/353
A61K 31/23

Abstract:

The invention relates to a medicament containing a compound of general formula (I), where R=independently, a straight or branched, saturated, singly- or multiply-unsaturated, optionally substituted C-Calkyl, alkylene or alkinyl group, preferably a C-Calkyl, alkylene or alkinyl group, particularly a C-Calkyl, alkylene or alkinyl group, most preferably a Calkyl group, R=independently, a straight or branched C-Calkyl, alkylene or alkinyl group, preferably a C-Calkyl, alkylene or alkinyl group, in particular a C-Calkyl, alkylene or alkinyl group, most preferably a Calkyl group, a —[CH—(CH)m—O]H group with n=1 to 10, preferably n=1 to 5, to m=1 to 5, preferably m=1 to 3, a —CH—[CH—(OH)][CH—R]-group, where R=independently H or OH, p=1 to 7, preferably p=1 to 4, a pentose group or a hexose group, as therapeutically active agent, alone or in combination with one or several further pharmaceutical agents as a combination preparation for the treatment of viral skin diseases and/or tumor diseases, in particular caused by human papilloma virus (HPV) and/or herpes viruses and a topically acting medicament formulation and the use thereof.

US Patent:

20180193254, Jul 12, 2018

Filed:

Aug 18, 2017

Appl. No.:

15/680819

Inventors:

- Melville NY, US
Robert LATHROP - Fort Collins CO, US
Erwin BÖHM - Ladenburg, DE
Irene GANDER-MEISTERERNST - Stockdorf, DE
Regina GREGER - Iffeldorf, DE
Johanna HOLLDACK - Aarhus C, DK
Ulrich MOEBIUS - Gauting-Unterbrunn, DE

Assignee:

Fougera Pharmaceuticals Inc. - Melville NY

International Classification:

A61K 9/00
A61K 47/06
A61K 31/23
A61K 31/353
A61K 47/10
A61K 47/14

Abstract:

The invention relates to a medicament containing a compound of general formula (I), where R=independently, a straight or branched, saturated, singly- or multiply-unsaturated, optionally substituted C-Calkyl, alkylene or alkinyl group, preferably a C-Calkyl, alkylene or alkinyl group, particularly a C-Calkyl, alkylene or alkinyl group, most preferably a Calkyl group, R=independently, a straight or branched C-Calkyl, alkylene or alkinyl group, preferably a C-Calkyl, alkylene or alkinyl group, in particular a C-Calkyl, alkylene or alkinyl group, most preferably a Calkyl group, a —[CH—(CH)m-O]H group with n=1 to 10, preferably n=1 to 5, to m=1 to 5, preferably m=1 to 3, a —CH—[CH—(OH)][CH—R]— group, where R=independently H or OH, p=1 to 7, preferably p=1 to 4, a pentose group or a hexose group, as therapeutically active agent, alone or in combination with one or several further pharmaceutical agents as a combination preparation for the treatment of viral skin diseases and/or tumor diseases, in particular caused by human papilloma virus (HPV) and/or herpes viruses and a topically acting medicament formulation and the use thereof.