Robert Dale Langley

US Patent:

7270645, Sep 18, 2007

Filed:

Jan 26, 2005

Appl. No.:

11/044887

Inventors:

Robert Warner Langley - Westminster CO, US
Larry Joe Dumont - Arvada CO, US

Assignee:

Gambro BCT, Inc - Lakewood CO

International Classification:

A61M 37/00
A61M 1/00
C02F 1/00
C02F 1/44
B04B 3/00

US Classification:

604 601, 604 401, 604 501, 604 604, 210645, 210739, 210782, 422 44, 422 67

Abstract:

A method and apparatus for producing blood component products. In one embodiment, a plurality of a predetermined type of blood component is harvested from a source of whole blood. At least two on-line yield determination techniques are utilized to determine the yield for the harvested blood components. One is a predetermined yield prediction technique and the second is a predetermined yield monitoring technique, each of which are individually calibrated in relation to a predetermined off-line yield determination technique. The predetermined yield prediction and monitoring techniques each provide the yield for the harvested blood components and each is then utilized to provide a determined yield. Consequently, when the harvested blood components are packaged the determined yield my be associated therewith, thereby providing a blood component product.

US Patent:

7704454, Apr 27, 2010

Filed:

Oct 8, 2003

Appl. No.:

10/680950

Inventors:

Robert W. Langley - Westminster CO, US
Thomas J. Felt - Boulder CO, US
Geert Van Waeg - Brussels, BE
Marlene Adele Bainbridge - Golden CO, US

Assignee:

CaridianBCT, Inc. - Lakewood CO

International Classification:

A61M 37/00
C02F 1/44

US Classification:

422 44, 604 401, 604 501, 210739

Abstract:

Methods, devices and device components are presented for blood processing. Particularly, methods, devices and device components are presented for separating blood into blood components and collecting one or more separated blood components, which reduce the incidence of blood vessel infiltration and enhance donor comfort. In one aspect, the invention provides blood processing methods having a return flow rate which decreases systematically during a return time. In another aspect, the invention provides blood processing methods having a removal flow rate, return flow rate or both which are derived from a subject's total blood volume. In another aspect, the present invention provides blood processing methods wherein the fraction by volume of removed blood corresponding to collected components is selected to optimize blood processing efficiency and enhance the purities of collected blood components.

US Patent:

7824355, Nov 2, 2010

Filed:

Aug 7, 2008

Appl. No.:

12/187988

Inventors:

Robert W. Langley - Westminster CO, US
Thomas J. Felt - Boulder CO, US
Geert Van Waeg - Brussels, BE
Marlene Adele Bainbridge - Golden CO, US

Assignee:

CaridianBCT, Inc. - Lakewood CO

International Classification:

A61M 37/00
A61M 1/00
A61M 5/00

US Classification:

604 401, 604 501, 604 616, 604 27, 604118, 604119, 422 44

Abstract:

Methods, devices and device components are presented for blood processing. Particularly, methods, devices and device components are presented for separating blood into blood components and collecting one or more separated blood components, which reduce the incidence of blood vessel infiltration and enhance donor comfort. In one aspect, the invention provides blood processing methods having a return flow rate which decreases systematically during a return time. In another aspect, the invention provides blood processing methods having a removal flow rate, return flow rate or both which are derived from a subject's total blood volume. In another aspect, the present invention provides blood processing methods wherein the fraction by volume of removed blood corresponding to collected components is selected to optimize blood processing efficiency and enhance the purities of collected blood components.

US Patent:

7857744, Dec 28, 2010

Filed:

Jun 19, 2007

Appl. No.:

11/765091

Inventors:

Robert W. Langley - Westminster CO, US
Linda A. Taylor - Littleton CO, US
Timothy Michael Taga - Broomfield CO, US

Assignee:

CaridianBCT, Inc. - Lakewood CO

International Classification:

B04B 7/08

US Classification:

494 45

Abstract:

A cell separation set for separating blood components, having a cell separation chamber with a first entry section having a wall with an outwardly flared curve, the entry section having an axial length and an inmost maximum diameter perpendicular to the axial length, the axial length being greater than the inmost maximum diameter. The cell separation chamber further comprises a separation section having a wall comprising an inward curve. A transition section between the entry section and the separation section has a wall comprising a second inward curve, the second inward curve being different from said first inward curve. The first curve may be tangent to the second curve at a first junction between the first and second curves and the second curve may be tangent to the third curve at a second junction between the second and third curves.

US Patent:

7963901, Jun 21, 2011

Filed:

Sep 12, 2008

Appl. No.:

12/209793

Inventors:

Robert W. Langley - Westminster CO, US
John Pittinger - Evergreen CO, US
Logan Fender - Lakewood CO, US

Assignee:

CaridianBCT, Inc. - Lakewood CO

International Classification:

B04B 7/12

US Classification:

494 45, 494 67, 210782

Abstract:

A disposable blood separation set of a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having a protruding inlet therein. The protruding inlet may have a frustro-conical inner surface that slants radially outwardly from an inlet to a mouth of the protruding inlet. A circumferential well may surround the protruding inlet. The cell separation chamber may have a baffle within a separation area. The baffle may have a plurality of vanes with openings therein.

US Patent:

8226537, Jul 24, 2012

Filed:

May 19, 2011

Appl. No.:

13/111039

Inventors:

John Pittinger - Evergreen CO, US
Robert Langley - Westminster CO, US
Mary Langley, legal representative - Westminster CO, US
Logan Fender - Lakewood CO, US

Assignee:

Terumo BCT, Inc. - Lakewood CO

International Classification:

B04B 7/12

US Classification:

494 45, 494 67

Abstract:

A disposable blood separation set of a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber a baffle within a separation area. The baffle may have a plurality of vanes with openings therein. A protruding inlet may have a frustro-conical inner surface that slants radially outwardly from an inlet to a mouth of the protruding inlet. A circumferential well may surround the protruding inlet.

US Patent:

20040096814, May 20, 2004

Filed:

Oct 30, 2003

Appl. No.:

10/699358

Inventors:

Robert Langley - Westminster CO, US
Larry Dumont - Arvada CO, US

Assignee:

Gambro, Inc.

International Classification:

A01N001/02
G06F019/00
G01N033/48
G01N033/50

US Classification:

435/002000, 702/019000

Abstract:

A method and apparatus for producing blood component products. In one embodiment, a plurality of a predetermined type of blood component is harvested from a source of whole blood. At least two on-line yield determination techniques are utilized to determine the yield for the harvested blood components. One is a predetermined yield prediction technique and the second is a predetermined yield monitoring technique, each of which are individually calibrated in relation to a predetermined off-line yield determination technique. The predetermined yield prediction and monitoring techniques each provide the yield for the harvested blood components and each is then utilized to provide a determined yield. Consequently, when the harvested blood components are packaged the determined yield my be associated therewith, thereby providing a blood component product.

US Patent:

20120015794, Jan 19, 2012

Filed:

Jul 5, 2011

Appl. No.:

13/176466

Inventors:

Brian M. HOLMES - Evergreen CO, US
Briden Ray STANTON - Highlands Ranch CO, US
Geert VAN WAEG - Brussels, BE
Robert Langley - Westminster CO, US
Mary Langley - Westminster CO, US

Assignee:

CARIDIANBCT, INC. - Lakewood CO

International Classification:

B01D 21/26

US Classification:

494 37

Abstract:

A method for controlling a centrifuge blood component separation system for separating components of a blood product, the separation system comprising a centrifuge and a separation bag and at least one transfer bag. The method comprises selecting a nominal hematocrit value such that an actual hematocrit value is expected to be less than said nominal hematocrit; centrifuging a separation bag containing a volume of composite liquid so as to cause the sedimentation of at least a first component and a second component; transferring some of the first component to a first transfer bag; detecting time of passage of a red blood cell interface at a pre-selected location in the separation bag; and adjusting a predicted processing time based on the time of passage of the red blood cell interface.

Author:

Robert A. Langley

ISBN #:

0883187566