Robert KUNKA - Research Triangle Park NC, US Tushar SHAH - Research Triangle Park NC, US
Assignee:
GLAXO GROUP LIMITED - Greenford
International Classification:
A61K 9/12 A61K 31/573
US Classification:
424045000, 514171000
Abstract:
A method for treating respiratory disorders by administrating by inhalation an effective amount of a β-receptor agonist, an acceptable amount of a corticosteriod, and HFA 134a, to a patient in need thereof, is disclosed. Preferably, the β-receptor agonist is salmeterol or a physiologically acceptable salt thereof, and the corticosteriod is fluticasone propionate or a solvate thereof. The combination of salmeterol, fluticasone proprionate, and HFA 134a may lower the risk of cardiac arrhythmias, sudden death, or hypercorticism that are sometimes associated with the simultaneous administration of a β-receptor agonist and an anti-inflammatory corticosteroid.
Robert KUNKA - Research Triangle Park NC, US Tushar SHAH - Research Triangle Park NC, US
Assignee:
GLAXO GROUP LIMITED - Greenford
International Classification:
A61K 31/573 A61K 9/12
US Classification:
424045000, 514171000
Abstract:
A method for treating respiratory disorders by administrating by inhalation an effective amount of a β-receptor agonist, an acceptable amount of a corticosteroid, and HFA 134, to a patient in need thereof, is disclosed. Preferably, the β-receptor agonist is salmeterol or a physiologically acceptable salt thereof, and the corticosteroid is fluticasone propionate or a solvate thereor. The combination of salmeterol, fluticasone proprionate, and HFA 134may lower the risk of cardiac arrhythmias, sudden death, or hypercorticism that are sometimes associated with the simultaneous administration of a β-receptor agonist and an anti-inflammatory corticosteroid.
Robert Kunka - Durham NC, US Tushar Shah - Flemington NJ, US
International Classification:
A61K031/573 A61L009/04
US Classification:
424/045000, 514/179000
Abstract:
A method for treating respiratory disorders by administrating by inhalation an effective amount of a -receptor agonist, an acceptable amount of a corticosteroid, and HFA 134, to a patient in need thereof, is disclosed. Preferably, the -receptor agonist is salmeterol or a physiologically acceptable salt thereof, and the corticosteroid is fluticasone propionate or a solvate thereof. The combination of salmeterol, fluticasone proprionate, and HFA 134may lower the risk of cardiac arrhythmias, sudden death, or hypercorticism that are sometimes associated with the simultaneous administration of a -receptor agonist and an anti-inflammatory corticosteroid.
The Kunka Group
President, the Kunka Group Inc
Gsk 2002 - 2007
Director
Gsk 1991 - 2002
Section Head and Group Leader
Chugai-Upjohn 1989 - 1991
Director, Clinical Trials Management
Gd Searle 1984 - 1989
Assistant and Associate Director, Drug Development and Pharmacokinetics
Education:
University of North Carolina at Chapel Hill 1971 - 1977
Doctorates, Doctor of Philosophy, Design, Philosophy
University of Illinois School of Pharmacy, Chicago, Il 1965 - 1970
Bachelors, Pharmacy
St. Laurence High School 1961 - 1965
Skills:
Pharmaceutical Industry Clinical Development Leadership Strategic Planning Clinical Trials Public Speaking Team Building Clinical Research Drug Development Fda Clinical Pharmacology Drug Discovery Therapeutic Areas Team Leadership Biotechnology Cro Oncology Respiratory Products Ind Pharmaceutics Protocol Regulatory Submissions Pharmacokinetics Regulatory Affairs Cancer Medical Writing Infectious Diseases R&D Biopharmaceuticals Validation Gcp Ctms Cross Functional Team Leadership Clinical Study Design Research