Robert R Gilmont

US Patent:

6440452, Aug 27, 2002

Filed:

Jul 31, 2001

Appl. No.:

09/919516

Inventors:

Riley S. Rees - Ann Arbor MI
Cynthia Marcelo - Ann Arbor MI
Belinda Adamson - Ann Arbor MI
Lenore Rhodes - Ann Arbor MI
Beverly Marchant - Ann Arbor MI
William Lindblad - Farmington MI
Robert Gilmont - Ann Arbor MI
Warren Garner - Ann Arbor MI
Cynthia Zuccaro - Dexter MI
Thomas E. Taddonio - Manchester MI

Assignee:

Regents of the University of Michigan - Ann Arbor MI

International Classification:

A61K 970

US Classification:

424443, 424489, 424490, 424484, 424422

Abstract:

Devices and methods for enhancing the healing of wounds, especially chronic wounds (e. g. , diabetic wounds), involving the use of keratinocytes are described. Keratinocytes are grown on a transplantable solid support (e. g. , collagen-coated beads), and the keratinocyte-coated solid support is placed in an enclosure. The enclosure, in turn, is placed in the wound for use as an interactive wound healing promoter.

US Patent:

6890552, May 10, 2005

Filed:

Jun 25, 2002

Appl. No.:

10/178342

Inventors:

Riley S. Rees - Ann Arbor MI, US
Cynthia Marcelo - Ann Arbor MI, US
Belinda Adamson - Ann Arbor MI, US
Lenore Rhodes - Ann Arbor MI, US
Beverly Marchant - Ann Arbor MI, US
William J. Lindblad - Farmington MI, US
Robert Gilmont - Ann Arbor MI, US
Warren Garner - Ann Arbor MI, US
Cynthia Zuccaro - Dexter MI, US
Thomas E. Taddonio - Manchester MI, US

Assignee:

Regents of the University of Michigan - Ann Arbor MI
Wayne State University - Detroit MI

International Classification:

A61F013/00
A01N025/34
A61K009/14
A61K009/20

US Classification:

424443, 424449, 424402, 424489, 424484, 424464

Abstract:

Devices and methods for enhancing the healing of wounds, especially chronic wounds (e. g. , diabetic wounds), involving the use of keratinocytes are described. Keratinocytes are grown on a transplantable solid support (e. g. , collagen-coated beads), and the keratinocyte-coated solid support is placed in an enclosure. The enclosure, in turn, is placed in the wound for use as an interactive wound healing promoter.

US Patent:

20010014674, Aug 16, 2001

Filed:

May 27, 1999

Appl. No.:

09/323188

Inventors:

RILEY S. REES - ANN ARBOR MI, US
ROBERT GILMONT - ANN ARBOR MI, US
BELINDA ADAMSON - ANN ARBOR MI, US

International Classification:

A61K031/665
C12N011/00

US Classification:

514/100000, 435/174000

Abstract:

Devices and methods for enhancing the healing of wounds, especially chronic wounds (e.g., diabetic wounds), involving the use of keratinocytes and transformed cells are described. A cell-coated transplantable solid support (e.g., beads coated with keratinocytes and/or transformed cells), are placed in an enclosure. The enclosure, in turn, is placed in the wound for use as an interactive wound healing promoter.

US Patent:

20020037566, Mar 28, 2002

Filed:

Feb 11, 2000

Appl. No.:

09/502479

Inventors:

Riley Rees - Ann Arbor MI, US
Robert Gilmont - Ann Arbor MI, US
Belinda Adamson - Ann Arbor MI, US
ELOF ERIKSSON - WELLESLEY MA, US
FENG YAO - NEEDHAM MA, US

International Classification:

A61K048/00
A01N063/00
C12N011/00
C12N011/16

US Classification:

435/174000, 424/093210

Abstract:

Devices and methods for enhancing the healing of wounds, especially chronic wounds (e.g., diabetic wounds), involving the use of keratinocytes and transformed cells are described. A cell-coated transplantable solid support (e.g., beads coated with keratinocytes and/or transformed cells), are placed in an enclosure. The enclosure, in turn, is placed in the wound for use as an interactive wound healing promoter.

US Patent:

61973300, Mar 6, 2001

Filed:

Jun 22, 1999

Appl. No.:

9/338413

Inventors:

Riley S. Rees - Ann Arbor MI
Cynthia Marcelo - Ann Arbor MI
Belinda Adamson - Ann Arbor MI
Lenore Rhodes - Ann Arbor MI
Beverly Marchant - Ann Arbor MI
William Lindblad - Farmington MI
Robert Gilmont - Ann Arbor MI
Warren Garner - Ann Arbor MI
Cynthia Zuccaro - Dexter MI
Thomas E. Taddonio - Manchester MI

International Classification:

A61K 970
A61K 914
A61K 916

US Classification:

424443

Abstract:

Devices and methods for enhancing the healing of wounds, especially chronic wounds (e. g. , diabetic wounds), involving the use of keratinocytes are described. Keratinocytes are grown on a transplantable solid support (e. g. , collagen-coated beads), and the keratinocyte-coated solid support is placed in an enclosure. The enclosure, in turn, is placed in the wound for use as an interactive wound healing promoter.

US Patent:

59723327, Oct 26, 1999

Filed:

Apr 16, 1997

Appl. No.:

8/840804

Inventors:

Riley S. Rees - Ann Arbor MI
Cynthia Marcelo - Ann Arbor MI
Belinda Adamson - Ann Arbor MI
Lenore Rhodes - Ann Arbor MI
Beverly Marchant - Ann Arbor MI
William Lindblad - Farmington MI
Robert Gilmont - Ann Arbor MI
Warren Garner - Ann Arbor MI
Cynthia Zuccaro - Dexter MI
Thomas E. Taddonio - Manchester MI

Assignee:

The Regents of the University of Michigan - Ann Arbor MI

International Classification:

C12N 500
C12N 1104
A01N 6300
A61F 1300

US Classification:

424 937

Abstract:

Devices and methods for enhancing the healing of wounds, especially chronic wounds (e. g. , diabetic wounds), are provided involving the use of keratinocytes. Keratinocytes are grown on a transplantable solid support (e. g. , collagen-coated beads), and the keratinocyte-coated solid support is placed in an enclosure. The enclosure, in turn, is placed in the wound for use as an interactive wound healing promoter. After the enclosure is placed in a wound, the wound may be covered with a dressing. The enclosure is degradable or non-degradable, and is constructed from a membrane or a porous polyester mesh material having pores that are either too small or large enough for keratinocytes to cross. A means may be attached to the enclosure to enable removing the enclosure from a wound.

US Patent:

62998986, Oct 9, 2001

Filed:

Dec 22, 2000

Appl. No.:

9/747742

Inventors:

Riley S. Rees - Ann Arbor MI
Cynthia Marcelo - Ann Arbor MI
Belinda Adamson - Ann Arbor MI
Lenore Rhodes - Ann Arbor MI
Beverly Marchant - Ann Arbor MI
William Lindblad - Farmington MI
Robert Gilmont - Ann Arbor MI
Warren Garner - Ann Arbor MI
Cynthia Zuccaro - Dexter MI
Thomas E. Taddonio - Manchester MI

Assignee:

Regents of the University of Michigan - Ann Arbor MI

International Classification:

A61K 970
A61K 914
A61K 916

US Classification:

424443

Abstract:

Devices and methods for enhancing the healing of wounds, especially chronic wounds (e. g. , diabetic wounds), involving the use of keratinocytes are described. Keratinocytes are grown on a transplantable solid support (e. g. , collagen-coated beads), and the keratinocyte-coated solid support is placed in an enclosure. The enclosure, in turn, is placed in the wound for use as an interactive wound healing promoter.