Robert L Fine

US Patent:

7772367, Aug 10, 2010

Filed:

Jan 27, 2005

Appl. No.:

10/587606

Inventors:

Robert L. Fine - Tenafly NJ, US
Paul Brandt-Rauf - Scarsdale NY, US
Yueha Mao - New York NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C07K 5/00
C07K 14/00
A61K 39/295

US Classification:

530350, 4241841

Abstract:

Disclosed are polypeptides comprising a first segment of continuous amino acids having the sequence AQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD (SEQ ID NO. 1) covalently linked to a second segment of continuous amino acids having the sequence DSDPGETKFMLKKHRSTSQGKKSKLHSSHARSGGPEKGAQA (SEQ ID NO. 2), or at least two of each covalently linked to each ether. The polypeptides are shown to induce apoptosis of cancer cells that contain mutant p53 or over-expressed wild-type p53.

US Patent:

20070050257, Mar 1, 2007

Filed:

Jun 8, 2006

Appl. No.:

11/423107

Inventors:

Robert Fine - Harriman NY, US
Bruce Bolger - Hastings on Hudson NY, US
James Kilmetis - Commack NY, US

Assignee:

SELLING COMMUNICATIONS, INC. - Irvington NY

International Classification:

G06Q 30/00

US Classification:

705014000

Abstract:

The present invention is an online publishing management system and method that includes at least one advertisement computer means for storing an advertisement file; at least one article computer means for storing an article file; and a publishing management server computer. The publishing management server computer includes user interface means for receiving data from and sending data to user, database means for storing a plurality of database tables, and processing means. The database tables include an advertisement table having a plurality of advertisement records, each advertisement record having information regarding an advertisement file stored on an advertisement computer means; an advertiser table having a plurality of advertiser records, each advertiser record having information regarding an advertiser associated with at least one advertisement file stored on an advertisement computer means; and an article table having a plurality of article records, each article record having information regarding an article file stored on an article computer means. The processing means is adapted to generate a plurality of reports as a function of one or more of the database tables; allow a user to input, via the user interface means, criteria for generating the reports; provide the reports to a user via the user interface means; and allow a user to enter or modify, via the user interface means, records in any of the database tables.

US Patent:

56480857, Jul 15, 1997

Filed:

Mar 15, 1995

Appl. No.:

8/403963

Inventors:

Christine L. Lanning - Durham NC
Mohammed B. Abou-Donia - Chapel Hill NC
Robert L. Fine - Durham NC
James J. Corcoran - Durham NC

Assignee:

Duke University - Durham NC

International Classification:

A01N 2500

US Classification:

424405

Abstract:

Pest populations that have developed pesticide resistance can be treated and killed with an inhibitor for ATP-dependent 150-180 kDa membrane P-glycoprotein as a pretreatment or simultaneously with application of a pesticide at doses which, by themselves, are not toxic to the pests.

US Patent:

54362431, Jul 25, 1995

Filed:

Nov 17, 1993

Appl. No.:

8/152894

Inventors:

Clifford W. Sachs - Durham NC
Robert L. Fine - Durham NC
Lawrence M Ballas - Apex NC
R. Ivy Carroll - Durham NC
Robert Bell - Durham NC

Assignee:

Research Triangle Institute Duke University - Research Triangle Park NC
Pharmaceuticals Corporation - Durham NC

International Classification:

A61K 31135
A61K 3155
A61K 31535
A61K 31445

US Classification:

5142318

Abstract:

Potentiating agents inhibit the development of multidrug resistance, reduce drug-resistance in drug-resistant tumors, or sensitize tumors to antineoplastic drugs, thereby potentiating the effect of antineoplastic agents. The potentiating agents are aminoanthraquinones, preferably 1,4-bis(N-substituted) amino anthraquinones, and pharmaceutically acceptable salts thereof.

Author:

Robert Fine

ISBN #:

0380755653

Author:

Robert Fine

ISBN #:

0442277512

Author:

Robert Fine

ISBN #:

0701166851

Author:

Robert Fine

ISBN #:

0714643130

Author:

Robert Fine

ISBN #:

0714647624

Author:

Robert Fine

ISBN #:

0745300456

Author:

Robert Fine

ISBN #:

0839768087

Author:

Robert Fine

ISBN #:

0853239657