Richard A. Hess - Bethesda MD Donald P. Tschudy - Chevy Chase MD
Assignee:
The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC
International Classification:
A61K 3119
US Classification:
514557
Abstract:
The present invention discloses a method of controlling graft versus host disease, resulting from bone marrow transplantation by treating the host with succinylacetone. A dosage of about 800 mg/kg body weight every 4 days is found optimal.
Richard W. Hess - Ellicott City MD Craig E. Finch - Petersburg MI
Assignee:
Bowles Fluidics Corporation - Columbia MD
International Classification:
F16B 710
US Classification:
403 52
Abstract:
A joint comprising a body member defining an annular groove and a pair of tangential notches intersecting the annular groove at diametrically opposed positions. A socket member is comprised of a preferably semispherically shaped frame having an open side and a pair of diametrically opposed knob or pin member. Each knob or pin member is engagable with one of the tangential notches to snap fit the body member within the semispherically shaped frame and within the annular groove. The body member is secured to a mounting bar and the semispherically shaped frame has an elongated slot and the mounting bar passes through the slot. The arrangement is such that the slot defines one path of rotation of the shaped frame member relative to the body member and the annular groove defines a second path of relative rotation between the body member and the shaped frame. Cooperating friction surfaces are formed on the frame and body members to control resistance to movement and maintain the members in their positions of adjustment.
Method For Treating Autoimmune Disease Using Succinylacetone
Richard A. Hess - Bethesda MD R. Michael Blaese - Rockville MD
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 3119
US Classification:
514557
Abstract:
The invention is a method of modulating or controlling autoimmune disease in a host. The method includes the step of administering to the diseased host a pharmaceutical effective amount of succinylacetone. The pharmaceutically effective amount of succinylacetone is desirably infused by an osmotic minipump in order to modulate the effects of autoimmune disease in the host.
A fluidic oscillator comprises a housing having interior walls defining a cylindrical space therein, a fluidic oscillator is mounted in said cylindrical space and has an oscillating chamber having an upstream end and a downstream end. A power nozzle issues a jet of fluid into the oscillation chamber from the upstream end thereof, an outlet formed in the downstream end. A pair of control ports at opposing sides of the power nozzle are coupled to a pair of feedback entranceways in the downstream end of the oscillator chamber and at corresponding opposing sides of the outlet. The control passageways connect each feedback entranceway with the a control port on the opposing sides, respectively. Each control passageway is formed in part by the interior wall and the oscillator element.
Richard W. Hess - Ellicott City MD Thomas G. Marsden - Rockville MD
Assignee:
Bowles Fluidics Corporation - Columbia MD
International Classification:
B05B 110
US Classification:
2392841
Abstract:
A windshield washer system has a nozzle mounted on a vehicle for issuing wash fluid to a windshield and a check valve for a fluid circuit from a supply of wash fluid to the nozzle. The nozzle has a fluid feed tube integrally formed therewith with annular walls defining a washer fluid flow path and a diameter of at least D. The feed tube has an external surface adapted to receive and retain a flexible hose from a supply of wash fluid. A spring shoulder receives a coil compression spring having upstream and downstream ends with the downstream end bearing on the spring shoulder. A valve element bears on the upstream end of the spring element, and a tubular insert having an inner end and an external diameter at least D and sufficient to form an elongated wash fluid seal with the annular walls defining a washer fluid flow path, and complementary-shaped valve seat formed on the inner end.
Method Of Preventing Graft Rejection In Solid Organ Transplantation
Richard A. Hess - Gaithersburg MD R. Michael Blaese - Rockville MD Christopher D. Stone - Bethesda MD
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 3119
US Classification:
514557
Abstract:
A method is disclosed for preventing graft rejection of transplanted solid organs, in mammal recipients thereof, by administering an effective graft rejection preventative amount of succinylacetone to said mammals.
Oct 2010 to 2000 Deputy Director Future OperationsUS Navy, Navy Expeditionary Guard Batallion, JTF GTMO
Aug 2009 to Oct 2010 Commanding OfficerUS Navy, National War College
Aug 2008 to Aug 2009 StudentUS Navy, Army 360th Civil Affairs Brigade
Apr 2007 to Aug 2008 Civil Affairs DirectorUS Navy, Regional Support Organization
Jun 2005 to Apr 2007 Chief Staff OfficerUS Navy, USS DWIGHT D. EISENHOWER (CVN 69)
Feb 2005 to Jun 2005 Damage Control AssistantUS Navy, USS SCOUT (MCM 8)
Apr 2002 to Feb 2004 Executive OfficerUS Navy, USS VANDEGRIFT (FFG 48)
Apr 2000 to Apr 2002 Combat Systems OfficerLine Two Communications Haymarket, VA Jul 1991 to Apr 2000 Owner/OperatorUS Navy
Jan 1991 to Jul 1991 Naval Air Logistics CoordinatorUS Navy, Deputy Assistant Secretary of the Navy, Manpower and Reserve Affairs
Jun 1990 to Jan 1991 Executive AssistantUS Navy, Commander, Readiness Command, Region SIX
Jun 1990 to Jan 1991 Flag LieutenantUS Navy, USS JOHN KING (DDG 3)
Jun 1986 to Jun 1990 Boilers Officer
Education:
National War College Fort McNair, DC 2009 to 2010 Masters of Science in National Security StrategyVirginia Tech 1985 Bachelor of Arts in Political Science