George Owoo - North Plainfield NJ, US Richard A. Burgos - Rahway NJ, US
Assignee:
Baxter International Inc. - Deerfield IL Baxter Healthcare S.A. - Glattpark (Opfikon)
International Classification:
A61K 31/47
US Classification:
514312
Abstract:
Formulations comprising argatroban and methods of making and using the formulations are provided. In an embodiment, the formulation comprises a solution having an argatroban concentration ranging from greater than about 10 to about 500 mg/mL. The solution can comprise an aqueous solution. The solution can be packaged in a sealed container that may either be aseptically-filled or subjected to sterilization to reduce the microbiological burden of the formulation. The solution can further be diluted and administered to persons needing same.
George Owoo - North Plainfield NJ, US Richard A. Burgos - Rahway NJ, US
Assignee:
Baxter International Inc. - Deerfield IL Baxter Healthcare S.A. - Glattpark (Opfikon)
International Classification:
A61K 31/47
US Classification:
514312
Abstract:
An aqueous, stable, sterile pharmaceutical composition of the thrombin inhibitor argatroban in a solution containing an acid to solubilize the argatroban, substantially free from dehydrated alcohol is described, as well as a method for its preparation.
George Owoo - North Plainfield NJ, US Richard A. Burgos - Rahway NJ, US
Assignee:
Baxter International Inc. - Deerfield IL Baxter Healthcare S.A. - Glattpark (Opfikon)
International Classification:
A61K 31/47
US Classification:
514312
Abstract:
An aqueous, stable, sterile pharmaceutical composition of the thrombin inhibitor argatroban in a solution containing an acid to solubilize the argatroban, substantially free from dehydrated alcohol is described, as well as a method for its preparation.
George Owoo - North Plainfield NJ, US Richard Burgos - Rahway NJ, US
International Classification:
A61K 31/4709
US Classification:
514312000
Abstract:
An aqueous, stable, sterile pharmaceutical composition of the thrombin inhibitor argatroban in a solution containing an acid to solubilize the argatroban, substantially free from dehydrated alcohol is described, as well as a method for its preparation.