Riccardo Alessandro

US Patent:

57444927, Apr 28, 1998

Filed:

Mar 10, 1994

Appl. No.:

8/209651

Inventors:

Elise C. Kohn - Olney MD
Lance A. Liotta - Potomac MD
Riccardo Alessandro - Bethesda MD

Assignee:

United States of America - Washington DC

International Classification:

A61K 3141

US Classification:

514359

Abstract:

Angiogenesis is a composite of regulated proliferation and regulated invasion occuring in a variety of normal and pathologic conditions. Compound 1 and related analogs are useful for inhibiting angiogenesis in a host and offer a novel approach to the treatment of cancer, diabetic retinopathy, hemangiomata, vasculidities and other diseases associated with angiogenesis.