Qiong Tang from 4910 March Brown Rd, Baltimore, MD 21075, age 48, Phone: 410 290-5787

Resumes

Senior Scientist

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Location:

Columbia, MD

Industry:

Food Production

Work:

Dsm
Senior Scientist
Advanced Bionutrition Corp May 2008 - Dec 2014
Research Scientist

Education:

University of Maryland
Doctorates, Doctor of Philosophy, Philosophy

Skills:

Lifesciences
Microbiology
Biotechnology
R&D

Languages:

Mandarin

Senior Scientist

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Location:

Columbia, MD

Work:

Nestlé Health Science
Senior Scientist

Qiong Tang

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Us Patents

Dry Storage Stabilizing Composition For Biological Materials
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US Patent:

20120039956, Feb 16, 2012
Filed:

Aug 12, 2011
Appl. No.:

13/208459
Inventors:

MOTI HAREL - PIKESVILLE MD, US
QIONG TANG - COLUMBIA MD, US
International Classification:

A61K 47/42
A61K 35/76
A61K 35/74
A61K 36/06
A61K 38/02
A61K 38/43
A61K 39/00
A61K 9/14
A61P 37/04
A61P 31/00
A23L 1/03
A23P 1/02
A23K 1/00
A23L 3/44
A23L 1/30
A23P 1/04
A61K 35/00
US Classification:

424400, 514773, 424 931, 424 936, 424 934, 424 9351, 514 11, 424 941, 4241841, 426654, 426 61, 426 62, 426103, 426648
Abstract:

The present invention includes compositions and drying methods for preserving sensitive bioactive materials, such as peptides, proteins, hormones, nucleic acids, antibodies, drugs vaccines, yeast, bacteria (probiotic or otherwise), viruses and/or cell suspensions, in storage. The compositions include a carbohydrates component and a glass enhancer component, wherein the carbohydrate component includes a mixture of di-, oligo- and polysaccharides and the glass enhancer includes ions of organic acid and protein hydrolysates. The composition is prepared by dispersing all the solid components in a solution and then snap-frozen to form small beads, strings or droplets. The preferred drying method of the frozen beads, strings or droplets is initiated by a short purging and structure stabilizing step of the frozen particles under a vacuum pressure of less than 2000 mTORR and at a desired temperature. During the secondary and final drying step of the material a full vacuum pressure and elevated temperature are applied, to achieve a final desirable water activity of the dry material.

Stabilizing Composition For Biological Materials
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US Patent:

20130296165, Nov 7, 2013
Filed:

Mar 25, 2013
Appl. No.:

13/849941
Inventors:

Qiong Tang - Columbia MD, US
Trisha Rice - Columbia MD, US
Kimberly Jennings - Laurel MD, US
Brian Carpenter - Baltimore MD, US
Roger Drewes - Hockessin DE, US
Elizabeth Raditsis - Columbia MD, US
January Scarbrough - Silver Spring MD, US
International Classification:

A61K 47/42
A23L 1/305
A01N 25/22
A23L 1/30
A61K 47/36
A61K 47/26
US Classification:

504100, 514773, 424 931, 424 941, 4241841, 424 934, 424 9351, 424 936, 424 9345, 514453, 514725, 424489, 426 61, 426 62, 426654, 426590, 264 28
Abstract:

Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20 C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw.

Stable Bioactive Substances And Methods Of Making
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US Patent:

20200154702, May 21, 2020
Filed:

Jan 24, 2020
Appl. No.:

16/751708
Inventors:

Moti Harel - Pikesville MD, US
Qiong Tang - Columbia MD, US
Erin E. Dickey - Laurel MD, US
International Classification:

A01N 25/10
A61K 9/14
A61K 47/26
A23L 33/00
A23L 33/10
A23K 20/189
A23K 20/163
A01N 25/22
A61K 38/44
A61K 38/48
A61K 9/20
A61K 38/47
C11D 3/39
C11D 3/386
C11D 3/00
A61K 38/46
C11D 3/48
C11D 3/33
C11D 3/22
A23K 40/20
A61K 31/714
Abstract:

The present invention relates to stable bioactive substances and preparation thereof. A preparation method includes dissolving a bioactive material in a solution substantially free of solutes to make a bioactive solution, adsorbing the bioactive solution onto dry polysaccharide particles to make bioactive loaded polysaccharide particles, and drying the bioactive loaded polysaccharide particles.

Stabilizing Methods For Coating Seeds With Biological Materials
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US Patent:

20190045704, Feb 14, 2019
Filed:

Feb 17, 2017
Appl. No.:

16/076416
Inventors:

- Columbia MD, US
Robert ACKERSON - Frankford DE, US
Qiong TANG - Elkridge MD, US
Stuart CANTOR - Mount Airy MD, US
Assignee:

Advanced Bionutrition Corp. - Columbia MD
International Classification:

A01C 1/06
A01N 63/00
C09D 105/00
C09D 7/40
Abstract:

The present invention provides a method for coating seeds with biological materials such as bacteria, fungi (e.g., yeasts and molds), parasites, recombinant vectors, and viruses. The method comprises (a) applying a moistening liquid to seeds to moisten seeds, wherein the moistening liquid comprises a moistening polymer, and (b) coating the moistened seeds with an effective amount of a dry composition, wherein the dry composition comprises biological materials, one or more disaccharides, one or more oligosaccharides, one or more polysaccharides, one or more carboxylic acid salts, and one or more hydrolyzed proteins. The coated seeds may have an initial water activity (Aw) below 0.4, and the microorganisms on the coated seeds have initial viability of at least 5 logs of colony forming units per gram of seeds (CFU/g seed). Also provided are coated seeds.

Stabilizing Composition For Biological Materials
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US Patent:

20170354737, Dec 14, 2017
Filed:

Aug 28, 2017
Appl. No.:

15/687730
Inventors:

- Columbia MD, US
Qiong Tang - Columbia MD, US
Trisha Rice - Columbia MD, US
Kimberly Jennings - Laurel MD, US
Brian Carpenter - Baltimore MD, US
Roger Drewes - Hockessin DE, US
Elizabeth Raditsis - Columbia MD, US
January Scarbrough - Silver Spring MD, US
Assignee:

Advanced BioNutrition Corporation - Columbia MD
International Classification:

A61K 47/42
A23L 33/125
A23K 20/147
A23L 33/14
A23K 20/163
A23L 33/15
A23L 33/135
A61K 47/40
A01N 25/22
A23K 50/40
A23L 33/18
A61K 9/19
A23L 33/105
A23K 20/174
A61K 47/26
A23L 33/19
A61K 47/36
A23K 10/18
Abstract:

Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20 C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw.

Stabilizing Composition For Biological Materials
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US Patent:

20170000892, Jan 5, 2017
Filed:

Sep 19, 2016
Appl. No.:

15/269171
Inventors:

- Columbia MD, US
Qiong Tang - Columbia MD, US
Trisha Rice - Columbia MD, US
Kimberly Jennings - Laurel MD, US
Brian Carpenter - Baltimore MD, US
Roger Drewes - Hockessin DE, US
Elizabeth Raditsis - Columbia MD, US
January Scarbrough - Silver Spring MD, US
Assignee:

Advanced BioNutrition Corporation - Columbia MD
International Classification:

A61K 47/42
A61K 47/40
A61K 47/26
A01N 25/22
A23L 33/135
A23L 33/14
A23L 33/18
A23L 33/15
A23K 50/40
A23K 10/18
A23K 20/174
A23K 20/147
A23K 20/163
A23L 33/125
A61K 47/36
Abstract:

Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20 C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw.

Stable Bioactive Substances And Methods Of Making
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US Patent:

20140271605, Sep 18, 2014
Filed:

Mar 12, 2014
Appl. No.:

14/205416
Inventors:

- Columbia MD, US
Qiong TANG - Columbia MD, US
Erin E. DICKEY - Laurel MD, US
Assignee:

ADVANCED BIONUTRITION CORP. - Columbia MD
International Classification:

A01N 25/10
A61K 38/48
A23K 1/165
A61K 31/714
C11D 3/386
A23L 1/30
A61K 47/36
A61K 38/46
US Classification:

424 946, 514777, 424 9464, 514 52, 504358, 510320, 510278, 510392, 427212, 427 214, 426 61
Abstract:

The present invention relates to stable bioactive substances and preparation thereof. A preparation method includes dissolving a bioactive material in a solution substantially free of solutes to make a bioactive solution, adsorbing the bioactive solution onto dry polysaccharide particles to make bioactive loaded polysaccharide particles, and drying the bioactive loaded polysaccharide particles.